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Search results for: PE
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Pediatria Medica e Chirurgica
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Revista Paulista de Pediatria
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Archivos Argentinos de Pediatria
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Sciences et Techniques en Perspective
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HUMAN NATURE-AN INTERDISCIPLINARY BIOSOCIAL PERSPECTIVE
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Vestnik St Petersburg University-Mathematics
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University of Pennsylvania Journal of Constitutional Law
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University of Pennsylvania Journal of International Law
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Dynamics of Antimicrobial Peptide Encapsulation in Carbon Nanotubes: The Role of Hydroxylation
PublicationIntroduction: Carbon nanotubes (CNTs) have been widely employed as biomolecule carriers, but there is a need for further functionalization to broaden their therapeutic application in aqueous environments. A few reports have unraveled biomolecule–CNT interactions as a measure of response of the nanocarrier to drug-encapsulation dynamics. Methods: Herein, the dynamics of encapsulation of the antimicrobial peptide HA-FD-13 (accession...
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DMSO and TMAO—Differences in Interactions in Aqueous Solutions of the K-Peptide
PublicationInteractions between a solvent and their co-solute molecules in solutions of peptides are crucial for their stability and structure. The K-peptide is a synthetic fragment of a larger hen egg white lysozyme protein that is believed to be able to aggregate into amyloid structures. In this study, a complex experimental and theoretical approach is applied to study systems comprising the peptide, water, and two co-solutes: trimethylamide...
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New Peptide Based Fluconazole Conjugates with Expanded Molecular Targets
PublicationInfections of Candida spp. etiology are frequently treated with azole drugs. Among azoles, the most widely used in the clinical scenario remains fluconazole (FLC). Promising results in treatment of dangerous, systemic Candida infections demonstrate the advantages of combined therapies carried out with combinations of at least two different antifungal agents. Here, we report five conjugates composed of covalently linked FLC and...
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Gemcitabine Peptide-Based Conjugates and Their Application in Targeted Tumor Therapy
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Immunosuppressive properties of amino acid and peptide derivatives of mycophenolic acid
PublicationMycophenolic acid (MPA) was coupled with amino acids and biologically active peptides including derivatives of tuftsin to modify its immunosuppressive properties. Both amino acid unit in the case of simple MPA amides and modifications within peptide moiety of MPA - tuftsin conjugates influenced the observed activity. Antiproliferative potential of the obtained conjugates was investigated in vitro and MPA amides with threonine methyl...
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Nutritional value, protein and peptide composition of edible cricket powders
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Elusive π-helical peptide foldamers spotted by chiroptical studies
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Coulomb-Assisted Dissociative Electron Attachment: Application to a Model Peptide
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Simulating Electron Transfer Attachment to a Positively Charged Model Peptide
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Bladder cancer detection using a peptide substrate of the 20S proteasome
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Structural Analysis of a Peptide Fragment of Transmembrane Transporter Protein Bilitranslocase
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Membrane structure and interactions of peptide hormones with model lipid bilayers
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The influence of substrate peptide length on human β‐tryptase specificity
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Anticancer Properties of Amino Acid and Peptide Derivatives of Mycophenolic Acid
PublicationBackground: Although Mycophenolic Acid (MPA) is applied as prodrugs in clinic as an immunosuppressant, it also possesses anticancer activity. MPA acts as Inosine-5’-Monophosphate Dehydrogenase (IMPDH) inhibitor, where the carboxylic group at the end of the side chain interacts with Ser 276 of the enzyme via hydrogen bonds. Therefore, MPA derivatives with other polar groups indicated high inhibition too. On the other hand, potent...
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Functionalized Peptide Fibrils as a Scaffold for Active Substances in Wound Healing
PublicationTechnological developments in the field of biologically active peptide applications in medicine have increased the need for new methods for peptide delivery. The disadvantage of peptides as drugs is their low biological stability. Recently, great attention has been paid to self-assembling peptides that can form fibrils. Such a formulation makes bioactive peptides more resistant to enzymatic degradation and druggable. Peptide fibrils...
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PEDIATRIC DRUGS
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Pediatric Rheumatology
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Pediatric Obesity
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Pediatric Reports
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Pediatric nursing
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PEDIATRIC TRANSPLANTATION
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PEDIATRIC CARDIOLOGY
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PEDIATRIC DIABETES
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PEDIATRIC RADIOLOGY
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PEDIATRIC RESEARCH
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PEDIATRIC ANNALS
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PEDIATRIC DENTISTRY
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PEDIATRIC ANESTHESIA
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PEDIATRIC NEUROSURGERY
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PEDIATRIC DERMATOLOGY
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PEDIATRIC PULMONOLOGY
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Pediatric Investigation
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PEDIATRIC NEPHROLOGY
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PEDIATRIC NEUROLOGY
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Pediatric Medicine
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Trypsin inhibitor, antioxidant and antimicrobial activities as well as chemical composition of potato sprouts originating from yellow- and colored-fleshed varieties
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World Journal of Pediatrics
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CURRENT OPINION IN PEDIATRICS
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Italian Journal of Pediatrics
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Case Reports in Pediatrics
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International Journal of Pediatrics
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Journal of Pediatrics Review
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