Search results for: BAGI
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[27.04.2022] Mid-term evaluation - Information Meeting for 2nd year PhD students
e-Learning CoursesInformation meeting on 27.04.2022 2nd-year PhD students
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[16.03.2023] Mid-term evaluation - Information Meeting for 2nd year PhD students
e-Learning CoursesInformation meeting on 16.03.2023 2nd-year PhD students
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[03.04.2023]Information meeting for Doctoral School candidates
e-Learning CoursesInformation meeting on 03.04.2023 Doctoral School candidates
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Molecular basis for the DNA damage induction and anticancer activity of asymmetrically substituted anthrapyridazone PDZ-7
Publicationnthrapyridazones, imino analogues of anthraquinone, constitute a family of compounds with remarkable anti-cancer activity. To date, over 20 derivatives were studied, of which most displayed nanomolar cytotoxicity towards broad spectrum of cancer cells, including breast, prostate and leukemic ones. BS-154, the most potent derivative, had IC50 values close to 1 nM, however, it was toxic in animal studies. Here, we characterize another...
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Utilizing Genome-Wide mRNA Profiling to Identify the Cytotoxic Chemotherapeutic Mechanism of Triazoloacridone C-1305 as Direct Microtubule Stabilization
PublicationRational drug design and in vitro pharmacology profiling constitute the gold standard in drug development pipelines. Problems arise, however, because this process is often dicult due to limited information regarding the complete identification of a molecule’s biological activities. The increasing aordability of genome-wide next-generation technologies now provides an excellent opportunity to understand a compound’s diverse eects...
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[25.11.2021] Information meeting for 1-st year PhD students
e-Learning CoursesInformation meeting on 25.11.2021 1st-year PhD students
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TARGETTELO New anticancer compounds interfering function of telomeres
ProjectsProject realized in Department of Pharmaceutical Technology and Biochemistry according to STRATEGMED3/306853/9/NCBR/2017 agreement from 2017-05-17
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Compounds modulating function of telomeric proteins TRF1 and TRF2
ProjectsProject realized in Department of Pharmaceutical Technology and Biochemistry
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InterPhD II nie dotyczy
ProjectsProject realized in Department of Pharmaceutical Technology and Biochemistry according to POWR.03.02.00-00-I002/16 agreement from 2017-09-25
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PG_go_West Szkoła Doktorska PG bliżej Europy
ProjectsProject realized in Doctoral School according to BPI/STE/2023/1/00018/U/00001 agreement from 2023-12-08
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Ne inhibitors of catalytic subunit of telomerase
ProjectsProject realized in Department of Pharmaceutical Technology and Biochemistry according to UMO-2014/13/B/NZ7/02207 agreement from 2015-01-28
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TARGETTELO New anticancer compounds interfering function of telomeres
ProjectsProject realized in Gdańsk University of Technology according to TRATEGMED3/306853/9/NCBR/2017 agreement from 2017-05-17
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Inter PhD Inter PhD
ProjectsProject realized in Department of Pharmaceutical Technology and Biochemistry according to UDA.POKL.04.01.01-00-368/09-00 agreement from 2009-12-31
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GUT Beyond Borders STE(E)R-ING towards International Doctoral School
ProjectsProject realized in Doctoral School according to PPI/STE/2020/1/00023/U/00001 agreement from 2020-12-11
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Katedra Technologii Leków i Biochemii
Research TeamsRacjonalne projektowanie, synteza i badanie właściwości biologicznych nowych związków o działaniu przeciwnowotworowym lub przeciwgrzybowym
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Justyna Płotka-Wasylka dr hab. inż.
PeopleUrodziła się w Słupsku (24.03.1986).W 2005 roku ukończyła I Liceum Ogólnokształcące im. Jana II Sobieskiego w Wejherowie i rozpoczęła studia na Wydziale Chemicznym Politechniki Gdańskiej. Po ich ukończeniu w 2010 rozpoczęła pracę naukową na tej uczelni, uzyskując w 2014 roku stopień doktora nauk chemicznych. Tematem jej rozprawy doktorskiej, wykonywanej pod kierunkiem prof. Marka Biziuka oraz dr Caluma Morrisona (Uniwersytet w...
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A common nonsense mutation of the BLM gene and prostate cancer risk and survival
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Novel sorptive extraction techniques in bioanalysis evaluated by Blue Applicability Grade Index: The paradigm of fabric phase sorptive extraction and capsule phase microextraction
PublicationFabric phase sorptive extraction (FPSE) and capsule phase microextraction (CPME) are two sol-gel derived microextraction techniques that emerged in the last decade towards the minimization of the environmental impact of conventional sample preparation approaches. Complementary to the well-established green metric tools, Blue Applicability Grade Index (BAGI) was recently proposed for the evaluation of method’s practicability. In...
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Deep eutectic solvent-based shaking-assisted extraction for determination of bioactive compounds from Norway spruce roots
PublicationPolyphenolic compounds play an essential role in plant growth, reproduction, and defense mechanisms against pathogens and environmental stresses. Extracting these compounds is the initial step in assessing phytochemical changes, where the choice of extraction method significantly influences the extracted analytes. However, due to environmental factors, analyzing numerous samples is necessary for statistically significant results,...
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CBM Collaboration
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CBM Collaboration
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