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Search results for: TRIPLEX DNA NANOSWITCHES
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DNA Computing and Molecular Programming (International Meeting on DNA Computing and Molecular Programming)
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Why do G-quadruplexes dimerize through the 5’-ends? Driving forces for G4 DNA dimerization examined in atomic detail
PublicationG-quadruplexes (G4) are secondary structures formed by guanine-rich nucleic acid sequences and shown to exist in living cells where they participate in regulation of gene expression and chromosome maintenance. G-quadruplexes with solvent-exposed guanine tetrads show the tendency to associate together through cofacial stacking, which may be important for packaging of G4-forming sequences and allows for the design of higher-order...
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CERVIX UTERI, Exocervix - Female, 46 - Cell image [4140730008823071]
Open Research DataThis is the histopathological image of CERVIX UTERI cell sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Comparative Analysis of CpG Sites and Islands Distributed in Mitochondrial DNA of Model Organisms
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Ancient mitochondrial DNA and the genetic history of Eurasian beaver (Castor fiber) in Europe
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Altered levels of circulating nuclear and mitochondrial DNA in patients with Papillary Thyroid Cancer
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Diet is Not Responsible for the Presence of Several Oxidatively Damaged DNA Lesions in Mouse Urine
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Selenium Supplementation Reduced Oxidative DNA Damage in Adnexectomized BRCA1 Mutations Carriers
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Comparison of Oxidative Stress/DNA Damage in Semen and Blood of Fertile and Infertile Men
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Confirmative electric DNA array-based test for food poisoning Bacillus cereus
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Theoretical Study of Damage to DNA by 0.2−1.5 eV Electrons Attached to Cytosine
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Wpływ dodatku kwasu deoksyrybonukleinowego (DNA) na właściwości mechaniczne żeli żelatynowych
PublicationKwasy nukleinowe cieszą się coraz większym zainteresowaniem pod względem zastosowania ich w przemyśle farmaceutycznym, kosmetycznym oraz żywnościowym. Określono wpływ dodatku długo- i krótkołańcuchowych kwasów nukleinowych na właściwości mechaniczne żeli żelatynowych. Badania wykazały występowanie specyficznych interakcji pomiędzy żelatyną a kwasami nukleinowymi oraz pozwoliły na ocenę wpływu tych oddziaływań na twardość, kohezyjność,...
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B26 Differential mitochondrial DNA levels in HD patients depending on the cell type
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C-1311 (Symadex), a potential anti-cancer drug, intercalates into DNA between A and G moieties. NMR-derived and MD-refined stereostructure of the d(GAGGCCTC) 2 :C-1311 complex
PublicationImidazoacridinone C-1311 (Symadex®) is an antitumor agent which has been recommended for Phase II clinical trials a few years ago. Previously, it was shown experimentally that during the initial stage of its action C-1311 forms stable intercalation complexes with DNA duplexes. Herein, a NMR-derived stereostructure of d(GAGGCCTC)2:C-1311 complex was reported. The ligand was found locating itself between A and G moieties, forming...
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DNA-reactive anticancer imidazoacridinone C-1311 is a new inhibitor of hypoxia-inducible factor 1 alpha, vascular endothelial growth factor and tumor angiogenesis
PublicationHypoxia-inducible factor 1 (HIF-1) plays a critical role for tumor adaptation to hypoxia and promotes angiogenesis. Antitumor imidazoacridinone C-1311 is a DNA reactive topoisomerase II and FLT3 receptor tyrosine kinase inhibitor selected for phase II clinical trials for breast cancer. Here, we demonstrate the new mechanism of C-1311 action involving HIF-1a, vascular endothelial growth factor (VEGF) and angiogenesis as additional...
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Characterization of a single-stranded DNA-binding-like Protein from Nanoarchaeum equitans - a nucleic acid binding protein with broad substrate specificity
PublicationBackground SSB (single-stranded DNA-binding) proteins play an essential role in all living cells and viruses, as they are involved in processes connected with ssDNA metabolism. There has recently been an increasing interest in SSBs, since they can be applied in molecular biology techniques and analytical methods. Nanoarchaeum equitans, the only known representative of Archaea phylum Nanoarchaeota, is a hyperthermophilic, nanosized,...
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DNA variants in Helicobacter pylori infected patients with chronic gastritis, dysplasia and gastric cancer
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DNA Variants in Helicobacter Pylori Infected Patients with Chronic Gastritis, Dysplasia and Gastric Cancer
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Tracking Clonal Evolution of Multiple Myeloma Using Targeted Next-Generation DNA Sequencing
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Influence of Selected Factors on the Survival Assessment and Detection of Giardia intestinalis DNA in Axenic Culture
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Population dynamics of Baltic herring since the Viking Age revealed by ancient DNA and genomics
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Mass Spectrometry-Based Analysis of DNA Modifications: Potential Applications in Basic Research and Clinic
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Endogenous oxidative DNA base modifications analysed with repair enzymes and GC/MS technique
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Preparation of Internal Standards for 2D-UPLC-MS/MS Quantification of Noncanonical DNA Bases
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Supplementation with antioxidant vitamins prevents oxidative modification of DNA in lymphocytes of HIV-infected patients
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Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair
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Aberrant repair of etheno–DNA adducts in leukocytes and colon tissue of colon cancer patients
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Oxidative stress and oxidative DNA damage is characteristic for mixed Alzheimer disease/vascular dementia
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Sample processing for DNA chip array-based analysis of enterohemorrhagic Escherichia coli (EHEC)
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A novel dual mode capacitor biosensor for real-time, label-free DNA detection
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Detection of bacteriophage infection and prophage induction in bacterial cultures by means of electric DNA chips
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Damage to Model DNA Fragments from Very Low-Energy (<1 eV) Electrons
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Cellular Turnover: A Potential Metabolic Rate–Driven Mechanism to Mitigate Accumulation of DNA Damage
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Bio-inspired Decisional DNA in Machinas and other Man-made Systems: The Way Forward
PublicationArtificial bio-inspired intelligent techniques and systems supporting smart, knowledge-based solutions of real world problems which are currently researched very extensively by research teams around the world, have enormous potential to enhance automation of decision making and problem solving for a number of diverse areas including design, manufacturing, Information Technology (IT), social communities of practice, and economics...
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One tube mutation detection using sensitive fluorescent dyeing of MutS protected DNA
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Preliminary studies on DNA retardation by MutS applied to the detection of point mutations in clinical samples
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Paweł Możejko dr hab.
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Oxidative DNA damage: assessment of the role in carcinogenesis, atherosclerosis, and acquired immunodeficiency syndrome1 1This article is part of a series of reviews on “Oxidative DNA Damage and Repair.” The full list of papers may be found on the homepage of the journal.
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Seafloor relief reconstruction from side scan sonar data
PublicationSide scan sonar is one of the most widely used imaging systems in the underwater environment. It is relatively cheap and easy to deploy, in comparison with more powerful sensors. Although side scan sonar does not provide seafloor bathymetry directly, its records are directly related to seafloor images. In the paper, the method for 3D seafloor relief reconstruction from side scan sonar data is presented. The method is based on the...
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ppGpp-Dependent Negative Control of DNA Replication of Shiga Toxin-Converting Bacteriophages in Escherichia coli
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Biomedical, Artificial Intelligence, and DNA Computing Photonics Applications and Web Engineering, Wilga, May 2012
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Influence of addition of cobalamin to the extender on the post-thaw motility, viability, and DNA integrity of bovine ejaculate
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Serial depletion of Baltic herring since the Viking Age revealed by ancient DNA and population genomics
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On the Trail of the Oldest Domestic Cat in Poland. An Insight from Morphometry, Ancient DNA and Radiocarbon Dating
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Buserelin Acetate Reduces Mortality and DNA Defragmentation of Bovine Sperm Cells Exposed to Oxidative Stress
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Bulky DNA adducts in human sperm: relationship with fertility, semen quality, smoking, and environmental factors
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Establishing the background level of base oxidation in human lymphocyte DNA: results of an interlaboratory validation study
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Urinary Measurement of 8-OxodG, 8-OxoGua, and 5HMUra: A Noninvasive Assessment of Oxidative Damage to DNA
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Mass spectrometry reveals the presence of specific set of epigenetic DNA modifications in the Norway spruce genome
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Critical factors for the performance of chip array-based electrical detection of DNA for analysis of pathogenic bacteria
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