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Search results for: PHAGE-BASED VACCINES
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Environmental Phage-Based Cocktail and Antibiotic Combination Effects onAcinetobacter baumanniiBiofilm in a Human Urine Model
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Discovery and characterization of RecA protein of thermophilic bacterium Thermus thermophilus MAT72 phage Tt72 that increases specificity of a PCR-based DNA amplification
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Bacteriophages as potential tools for use in antimicrobial therapy and vaccine development
PublicationThe constantly growing number of people suffering from bacterial, viral, or fungal infections, parasitic diseases, and cancers prompts the search for innovative methods of disease prevention and treatment, especially based on vaccines and targeted therapy. An additional problem is the global threat to humanity resulting from the increasing resistance of bacteria to commonly used antibiotics. Conventional vaccines based on bacteria...
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Vaccines
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Phage Therapy—Challenges, Opportunities and Future Prospects
PublicationThe increasing drug resistance of bacteria to commonly used antibiotics creates the need to search for and develop alternative forms of treatment. Phage therapy fits this trend perfectly. Phages that selectively infect and kill bacteria are often the only life-saving therapeutic option. Full legalization of this treatment method could help solve the problem of multidrug-resistant infectious diseases on a global scale. The aim of...
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The Perception and Attitudes toward COVID-19 Vaccines: A Cross-Sectional Study in Poland
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Evaluation of Whole-Cell and Acellular Pertussis Vaccines in the Context of Long-Term Herd Immunity
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Phage-Directed Synthesis of Photoluminescent Zinc Oxide Nanoparticles under Benign Conditions
PublicationBiological systems, especially bacteriophages and peptides, are an attractive green alternative to other known methods of nanoparticle synthesis. In this work, for the first time, bacteriophages were employed to synthesize a specific peptide, capable of producing nanoparticles (NPs). Derivatives of M13 bacteriophage exposing a ZnO-binding peptide (TMGA-LGLKWPV) on either pIII or pVIII phage coat protein were constructed and used...
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Sports Elite Means Vaccine Elite? Concerns and Beliefs Related to COVID-19 Vaccines among Olympians and Elite Athletes
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KNOWLEDGE-BASED SYSTEMS
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npj Vaccines
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Human Vaccines
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Roads to the development of improved pertussis vaccines paved by immunology
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Phage therapy as a novel strategy in the treatment of urinary tract infections caused by E. coli
PublicationUrinary tract infections (UTIs) are regarded as one of the most common bacterial infections affecting millions of people, in all age groups, annually in the world. The major causative agent of complicated and uncomplicated UTIs are uropathogenic E. coli strains (UPECs). Huge problems with infections of this type are their chronicity and periodic recurrences. Other disadvantages that are associated with UTIs are accompanying complications...
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Ochrona Przeciwkorozyjna Instalacji Przemysłowych i Risk Based Inspection (RBI)
e-Learning CoursesRisk Based Inspection
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PHAGE-Therapy Applications and Research
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Grzegorz Boczkaj dr hab. inż.
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Reliability Based zoptimization 2023/24
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[ILiT, IŚGiE] Reliability-Based Optimization (RBO)
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Safety and Impact on Training of the Influenza Vaccines in Elite Athletes Participating in the Rio 2016 Olympics
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Nanoparticles Influence Lytic Phage T4-like Performance In Vitro
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Regulation of replication of λ phage and λ plasmid DNAs at low temperature
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Characterization of DNA Polymerase from Thermus thermophilus MAT72 Phage Tt72
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Therapeutic Advances in Vaccines and Immunotherapy
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Interactions of Bacteriophages with Animal and Human Organisms—Safety Issues in the Light of Phage Therapy
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[ILiT, IŚGiE] Reliability-Based Optimization (RBO) - 2022/23
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[ILiT, IŚGiE] Reliability-Based Optimization (RBO) - 2023/24
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Marcin Wekwejt dr inż.
PeopleMarcin Wekwejt holds a bachelor’s degree in Biomedical Engineering (2016; J. and J. Śniadecki Bydgoszcz University of Technology & L. Rydygier Collegium Medicum), a master’s degree in Mechanical-Medical Engineering (2018; Gdańsk University of Technology & Gdańsk Medical University), and a PhD in Materials Engineering (2021; Gdańsk University of Technology). He was awarded the title of Doctor of Engineering and Technical...
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Activity of Phage–Lactoferrin Mixture against Multi Drug Resistant Staphylococcus aureus Biofilms
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Persistence of bacteriophage T4 in a starved Escherichia coli culture: evidence for the presence of phage subpopulations
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Tropical Diseases, Travel Medicine and Vaccines
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Double-Layer Agar (DLA) Modifications for the First Step of the Phage-Antibiotic Synergy (PAS) Identification
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Rotating Magnetic Field-Assisted Reactor Enhances Mechanisms of Phage Adsorption on Bacterial Cell Surface
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Evidence-Based Practice
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Evidence-based nursing
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Evidence Based Midwifery
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Evidence-based dentistry
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Evidence-Based Medicine
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Intelligence-Based Medicine
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Human Vaccines & Immunotherapeutics
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The Influence of Bacteriophages on the Metabolic Condition of Human Fibroblasts in Light of the Safety of Phage Therapy in Staphylococcal Skin Infections
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Biological aspects of phage therapy versus antibiotics against Salmonella enterica serovar Typhimurium infection of chickens
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The cell surface protein Ag43 facilitates phage infection of Escherichia coli in the presence of bile salts and carbohydrates
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Reverse vaccinology-based prediction of a multi-epitope SARS-CoV-2 vaccine and its tailoring to new coronavirus variants
PublicationThe genome feature of SARS-CoV-2 leads the virus to mutate and creates new variants of concern. Tackling viral mutations is also an important challenge for the development of a new vaccine. Accordingly, in the present study, we undertook to identify B- and T-cell epitopes with immunogenic potential for eliciting responses to SARS-CoV-2, using computational approaches and its tailoring to coronavirus variants. A total of 47 novel...
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Biochemical Characterization and Validation of a Catalytic Site of a Highly Thermostable Ts2631 Endolysin from the Thermus scotoductus Phage vB_Tsc2631
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ClpP/ClpX-mediated degradation of the bacteriophage λ O protein and regulation of λ phage and λ plasmid replication
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Immunization with whole cell but not acellular pertussis vaccines primes CD4 T RM cells that sustain protective immunity against nasal colonization with Bordetella pertussis
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Structure and function of the Ts2631 endolysin of Thermus scotoductus phage vB_Tsc2631 with unique N-terminal extension used for peptidoglycan binding
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Excess production of phage λ delayed early proteins under conditions supporting high Escherichia coli growth rates
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Antibiotics Act with vB_AbaP_AGC01 Phage against Acinetobacter baumannii in Human Heat-Inactivated Plasma Blood and Galleria mellonella Models
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