Search results for: PHOSPHOLIPID HYDROLYSIS

• Effect of oxidation and in vitro intestinal hydrolysis on phospholipid toxicity towards HT29 cell line serving as a model of human intestinal epithelium

  Publication

  • K. Parchem
  • M. Baranowska
  • A. Kościelak
  • I. E. Kłosowska-Chomiczewska
  • M. R. Domingues
  • A. Macierzanka
  • A. Bartoszek-Pączkowska

  - FOOD RESEARCH INTERNATIONAL - Year 2023

  Oxidation of food-derived phospholipids (PLs) can influence nutrient digestion and induce oxidative stress in gastrointestinal epithelium. In this study, hen egg yolk PL fraction was used to evaluate the effect of lipoxygenase (LOX)-induced PL oxidation on the rate of PL hydrolysis catalyzed by pancreatic phospholipase A2 (PLA2) in the presence of bile salts (BSs). Then, PL/BS solutions containing native or oxidized PLs were used...

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