Search results for: ASTROCYTES

• Variances in the Expression Profile of Circadian Clock-Related Genes in Astrocytic Brain Tumors

  Publication

  • R. Staszkiewicz
  • D. Sobański
  • W. Pulka
  • D. Gładysz
  • M. Gadzieliński
  • D. Strojny
  • B. Grabarek

  - Cancers - Year 2024

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• FTY720 Attenuates Infection-Induced Enhancement of Aβ Accumulation in APP/PS1 Mice by Modulating Astrocytic Activation

  Publication

  • R. McManus
  • O. Finucane
  • M. Wilk
  • K. Mills
  • M. Lynch

  - Journal of Neuroimmune Pharmacology - Year 2017

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• Nitric Oxide-Dependent Pathways as Critical Factors in the Consequences and Recovery after Brain Ischemic Hypoxia

  Publication

  • J. M. Wierońska
  • P. Cieślik
  • L. Kalinowski

  - Biomolecules - Year 2021

  Brain ischemia is one of the leading causes of disability and mortality worldwide. Nitric oxide (NO), a molecule that is involved in the regulation of proper blood flow, vasodilation, neuronal and glial activity constitutes the crucial factor that contributes to the development of pathological changes after stroke. One of the early consequences of a sudden interruption in the cerebral blood flow is the massive production of reactive...

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• Natural fish oil improves the differentiation and maturation of oligodendrocyte precursor cells to oligodendrocytes in vitro after interaction with the blood–brain barrier

  Publication

  • P. Piatek
  • N. Lewkowicz
  • S. Michlewska
  • M. Wieczorek
  • R. Bonikowski
  • K. Parchem
  • P. Lewkowicz
  • M. Namiecinska

  - Frontiers in Immunology - Year 2022

  The blood–brain barrier (BBB) tightly controls the microenvironment of the central nervous system (CNS) to allow neurons to function properly. Additionally, emerging studies point to the beneficial effect of natural oils affecting a wide variety of physiological and pathological processes in the human body. In this study, using an in vitro model of the BBB, we tested the influence of natural fish oil mixture (FOM) vs. borage oil...

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• Immunophenotyping and transcriptional profiling of in vitro cultured human adipose tissue derived stem cells

  Publication

  • A. Mieczkowska
  • A. Schumacher
  • N. Filipowicz
  • A. Wardowska
  • M. Zieliński
  • P. Madanecki
  • E. Nowicka
  • P. Langa
  • M. Deptuła
  • J. Zieliński... and 14 others

  - Scientific Reports - Year 2018

  Adipose-derived stem cells (ASCs) have become an important research model in regenerative medicine. However, there are controversies regarding the impact of prolonged cell culture on the ASCs phenotype and their differentiation potential. Hence, we studied 10 clinical ASCs replicates from plastic and oncological surgery patients, in six-passage FBS supplemented cultures. We quantified basic mesenchymal cell surface marker transcripts...

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