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Search results for: PHARMACOLOGICAL REGENERATION
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Pharmacological Reports
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Discovery of small-molecule regenerative drugs using a model of complex tissue injury in mice. Transcriptomic responses of neurodevelopmental genes during pharmacologically induced regeneration
PublicationDespite significant development in regenerative medicine, there is a deficit of effective therapies for wound healing and tissue regeneration. Research performed using animal wound models allows for a better understanding of this complex process, searching for compounds with pro-regenerative properties, and assessing their efficacy and safety. Unfortunately, the lack of adequate preclinical models proves to be an issue as no animal...
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Regeneration
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Cell Regeneration
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Inflammation and Regeneration
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Engineered Regeneration
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New possible pharmacological targets for statins and ezetimibe
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Nocturnal Enuresis: A Synopsis of Behavioral and Pharmacological Management
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Potentilla—A review of its phytochemical and pharmacological profile
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Advances in Pharmacological Sciences
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Chinese Pharmacological Bulletin
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JOURNAL OF PHARMACOLOGICAL SCIENCES
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TRENDS IN PHARMACOLOGICAL SCIENCES
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Neural Regeneration Research
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Competence of Polish primary‐care doctors in the pharmacological treatment of hypertension
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Regenerative Therapy
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Regenerative Biomaterials
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Regenerative Medicine
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Ficus plants: State of the art from a phytochemical, pharmacological, and toxicological perspective
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ACTA PHARMACOLOGICA SINICA
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Folia Pharmacologica Japonica
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Prolonged pharmacological inhibition of cathepsin C results in elimination of neutrophil serine proteases
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Structural and Pharmacological Characterization of Phenylalanine-Based AMPA Receptor Antagonists at Kainate Receptors
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JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
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Advances in Pharmacological and Pharmaceutical Sciences
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Journal of Urban Regeneration and Renewal
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Insight into heart regeneration
PublicationThe mammalian heart is thought to be incapable of regeneration because of the limited ability of cardiomyocytes. to proliferate. However, it has been recently shown that the neonatal murine heart is able to restore its normal function after coronary artery ligation or even partial resection. Unfortunately, this feature is lost in a few days after birth, although lower vertebrates as zebrafish or newt, retain this ability until adulthood. Therefore,...
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The role of epigenetics in regeneration
PublicationComplex changes in chromatin structure and at the transcriptional level occur from the creation of a single parental gamete throughout fertilization, embryo development and the life of an adult organism. Epigenetic changes, such as methylation and hydroxymethylation of DNA or histone methylation and acetylation, are an important part of these processes. Epigenetic regulation has an essential influence on gene expression level. DNA...
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Synthesis, Pharmacological Evaluation, and Computational Studies of Cyclic Opioid Peptidomimetics Containing β3-Lysine
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Pharmacological Profile and Molecular Modeling of Cyclic Opioid Analogues Incorporating Various Phenylalanine Derivatives
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New Insights into Dietary Supplements Used in Sport: Active Substances, Pharmacological and Side Effects
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Efficacy of the Whole-Body Cryotherapy as Add-on Therapy to Pharmacological Treatment of Depression—A Randomized Controlled Trial
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Desert Endemic Plants in Algeria: A Review on Traditional Uses, Phytochemistry, Polyphenolic Compounds and Pharmacological Activities
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Non-Pharmacological Treatments for Insulin Resistance: Effective Intervention of Plant-Based Diets—A Critical Review
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Imidazoacridinone-dependent lysosomal photodestruction: a pharmacological Trojan horse approach to eradicate multidrug-resistant cancers
PublicationMultidrug resistance (MDR) remains a primary hindrance to curative cancer therapy. Thus, introduction of novel strategies to overcome MDR is of paramount therapeutic significance. Sequestration of chemotherapeutics in lysosomes is an established mechanism of drug resistance. Here, we show that MDR cells display a marked increase in lysosome number. We further demonstrate that imidazoacridinones (IAs), which are cytotoxic fluorochromes,...
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Identity and authenticity in urban regeneration
PublicationArtykuł dotyczy zagadnienia relacji pomiędzy kwestiami ochrony autentyzmu a budowy jego tożsamości w programach rewitalizacji urbanistycznej.
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Polydopamine Biomaterials for Skin Regeneration
PublicationDesigning biomaterials capable of biomimicking wound healing and skin regeneration has been receiving increasing attention recently. Some biopolymers behave similarly to the extracellular matrix (ECM), supporting biointerfacial adhesion and intrinsic cellular interactions. Polydopamine (PDA) is a natural bioadhesive and bioactive polymer that endows high chemical versatility, making it an exciting candidate for a wide range of...
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npj Regenerative Medicine
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Regenerative Medicine Research
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Current Regenerative Medicine
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Pharmacological Research - Modern Chinese Medicine
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Pharmacological characterization and binding modes of novel racemic and optically active phenylalanine-based antagonists of AMPA receptors
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Cross-talk between DNA damage and cell survival checkpoints during G2 and mitosis: pharmacological implications
PublicationW pracy wyjaśnialiśmy rolę surwiwiny w ochronie komórek w czasie przejścia między G2 i mitozą, traktowanych związkiem uszkadzającym DNA. Jako model komórkowy wybraliśmy komórki ludzkiej białaczki MOLT-4, które wykazują zwiększoną ekspresję białka surwiwiny i niefunkcjonalnym p53. Ekspozycja tych komórek na melfalan, klasyczny związek uszkadzający DNA, prowadzi do uruchomienia punktu kontrolnego w G2 i zablokowania progresji cyklu...
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Power Generation Technology
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Urban Waterfront Regeneration: Origins of the Issue
PublicationThis paper deals with the origins of the issue of urban waterfront regeneration. The process of city-water interface was described with references to the three generations of port structures.
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Challenges of Cogeneration
PublicationPrzedstawiono problemy skojarzonego wytwarzania ciepła i energii elektrycznej w Polsce. Omówiono układy technologiczne i problemy sprawności wytwarzania skojarzonego. podano przykłady problemów, które powinny być rozwiązane w nowych warunkach ekonomicznych zarówno w dziedzinie optymalizacji ekonomicznej jak i technologicznej.
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Neutrophil proteinase 3 and dipeptidyl peptidase I (cathepsin C) as pharmacological targets in granulomatosis with polyangiitis (Wegener granulomatosis)
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Editorial: Food/Diet Supplements From Natural Sources: Current Status and Future Challenges From a Pharmacological Perspective
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From Regenerative Buildings to Regenerative Urban Projects: Design frameworks to scale up within the area of regenerative practice
PublicationIn this chapter, a discussion will be presented of design frameworks and assessment tools that are useful for boosting the scale jumping of regenerative design practices and the paradigm shift. Our main objectives will be to identify existing design and assessment frameworks, to describe the way they work and how they can contribute to scale-jumping regenerative design, as well as to identify shortcomings and opportunities. We...
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Piotr Lorens prof. dr hab. inż. arch.
PeopleProf. Piotr Lorens - PhD, DSc., urban planner. Lecturer in urban design and development and - since 2007 - Head of the Department of Urban Design and Regional Planning at the Faculty of Architecture, Gdansk University of Technology. His university activities also include coordination of the research and EU Social Fund projects. Based on these projects he was responsible for organization and coordination of the post-graduate studies...