Filters
total: 2872
displaying 1000 best results Help
Search results for: REDUCTIVE METABOLISM
-
Evaluation of bioconcentration and metabolism of diclofenac in mussels Mytilus trossulus - laboratory study
Publication -
Activities of genes controlling sphingolipid metabolism in human fibroblasts treated with flavonoids
Publication -
Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids
Publication -
Ascorbate and glutathione metabolism in embryo axes and cotyledons of germinating lupine seeds
Publication -
The II phase metabolism of endogenous and exogenous compounds, including antitumor chemotherapeutics
PublicationThe II phase metabolism, it is a set of metabolism and excretion pathways of endogenous as well as exogenous compounds including xenobiotics. UDP-glucuronyltransferases (UGTs; EC 2.4.1.17) are the most crucial representatives of II phase enzymes, which are responsible for the transformation of bilirubine and bile acids, steroids and thyroid hormones and lipids. Exogenous compounds, including drugs, carcinogens, environmental pollutants...
-
Phase I and phase II metabolism simulation of antitumor-active 2-hydroxyacridinone with electrochemistry coupled on-line with mass spectrometry.
PublicationHere, we report the metabolic profile and the results of associated metabolic studies of 2-hydroxyacridinone (2-OH-AC), the reference compound for antitumor-active imidazo- and triazoloacridinones. Electrochemistry coupled with mass spectrometry was applied to simulate the general oxidative metabolism of 2-OH-AC for the first time. The reactivity of 2-OH-AC products to biomolecules was also examined. The usefulness of the electrochemistry...
-
DIABETES OBESITY & METABOLISM
Journals -
Journal of Endocrinology and Metabolism
Journals -
Nutritional Therapy & Metabolism
Journals -
Journal of Nutrition and Metabolism
Journals -
Archives of Endocrinology Metabolism
Journals -
Cardiovascular Endocrinology & Metabolism
Journals -
Diabetes & Metabolism Journal
Journals -
Drug Metabolism and Pharmacokinetics
Journals -
DIABETES NUTRITION & METABOLISM
Journals -
Journal of Diabetes & Metabolism
Journals -
Drug Metabolism Letters
Journals -
Human Nutrition and Metabolism
Journals -
MOLECULAR GENETICS AND METABOLISM
Journals -
METABOLISM-CLINICAL AND EXPERIMENTAL
Journals -
Obesity and Metabolism-Milan
Journals -
Endocrinology, Diabetes and Metabolism
Journals -
Journal of Bone Metabolism
Journals -
Metabolic syndrome: a psychiatric outlook
Publication -
Regulation of carbon catabolism in Lactococcus lactis
Publication -
Caffeine Inhibits Differentiation Of Lung Cancer Stem Cells By Modulating Their Respiratory Metabolism
PublicationIt is ell established that many tumor types contain a fraction of cells, with stem cell-like properties, called cancer stem cells (CSCs), that are resistant to apoptosis induced by therapeutic agents. The presence of CSCs may explain why a standard anticancer treatment, that eliminates only differentiated cancer cells, does not lead to cancer cure.We previously showed the existence of caffeine-sensitive mechanism that controls...
-
Uptake, tissue distribution, and metabolism of malachite green in the channel catfish (Ictalurus punctatus)
Publication -
Metabolism of Tryptophan and Depressive Symptoms Six Months after Interferon- alfa Treatment
Publication -
Research Trends of Vitamin D Metabolism Gene Polymorphisms Based on a Bibliometric Investigation
Publication -
ClaR—a novel key regulator of cellobiose and lactose metabolism in Lactococcus lactis IL1403
Publication -
Effects of Single and Repeated Footshock on Dopamine Release and Metabolism in the Brains of Fischer Rats
Publication -
Erratum to: Activities of genes controlling sphingolipid metabolism in human fibroblasts treated with flavonoids
Publication -
The Phytoestrogen Genistein Modulates Lysosomal Metabolism and Transcription Factor EB (TFEB) Activation
Publication -
Cytochromes P-450: specyfic enzymes involved in metabolism of endogenous substances and xenobiotics
PublicationCytochromy P-450 to grupa enzymów hemoproteinowych występujących w prawie wszystkich organizmach żywych. Substratami tych enzymów są zarówno substancje endogenne jak i ksenobiotyki, włączając w to leki, dodatki do żywności oraz zanieczyszczenia środowiska. W pracy omówiono rolę polimorfizmu oraz indukcji P-450 w metabolizmie leków przeciwnowotworowych.
-
RIE. Revista de investigación educative
Journals -
International Journal of Disaster Risk Reduction
Journals -
Health economy of the metabolic syndrome pandemic
Publication -
METABOLIC BRAIN DISEASE
Journals -
Interspecific allelopathy in cyanobacteria: Cylindrospermopsin and Cylindrospermopsis raciborskii effect on the growth and metabolism of Microcystis aeruginosa
Publication -
Characterization of In Vitro and In Vivo Metabolism of Antazoline Using Liquid Chromatography-Tandem Mass Spectrometry
Publication -
Glucose metabolism disorders in patients with non-functioning adrenal adenomas — single-centre experience
PublicationIntroduction: The presence of glucose metabolism disorders and their possible correlation with degree of cortisol secretion were evaluated in patients with non-functioning adrenal incidentalomas (NFAIs). Material and methods: The study group consisted of 131 patients with hormonally inactive adrenal incidentalomas....
-
Correction: Corrigendum: Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids
Publication -
Correction: Corrigendum: Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids
Publication -
Productive aging
PublicationThe term “productive aging” refers to the participation of older adults in different activities that contribute to generating goods and services and develop the capacity to produce goods and services. In that sense, it includes both the economic activity of this group – serving in the paid workforce – and its social productivity, understood as volunteer activities (Bass et al. 1993). In the broader sense, “productive aging” can...
-
Electrochemistry/mass spectrometry (EC/MS) for fast generation and identification of novel reactive metabolites of two unsymmetrical bisacridines with anticancer activity.
PublicationThe development of a new drug requires knowledge about its metabolic fate in a living organism, regarding the comprehensive assessment of both drug therapeutic activity and toxicity profiles. Electrochemistry (EC) coupled with mass spectrometry (MS) is an efficient tool for predicting the phase I metabolism of redox-sensitive drugs. In particular, EC/MS represents a clear advantage for the generation of reactive drug transformation...
-
DRUG METABOLISM AND DISPOSITION
Journals -
DRUG METABOLISM REVIEWS
Journals -
Integrating conventional nitrogen removal with anammox in wastewater treatment systems: Microbial metabolism, sustainability and challenges
PublicationThe various forms of nitrogen (N), including ammonium (NH4+), nitrite (NO2−), and nitrate (NO3−), present in wastewaters can create critical biotic stress and can lead to hazardous phenomena that cause imbalances in biological diversity. Thus, biological nitrogen removal (BNR) from wastewaters is considered to be imperatively urgent. Therefore, anammox-based systems, i.e. partial nitrification and anaerobic ammonium oxidation (PN/anammox)...
-
Photosynthesis and sucrose metabolism in leaves of Arabidopsis thaliana aos, ein4 and rcd1 mutants as affected by wounding
Publication -
Metabolism of 1α-hydroxyvitamin D3 by cytochrome P450scc to biologically active 1α,20-dihydroxyvitamin D3
Publication