Open Research Data

• Measurement of cytotoxicity using the MTT test of oxytetracycline hydrochloride in a range of selected concen-trations

  Open Research Data

  open access

  • M. Wieczerzak
  • B. Kudłak
  • J. Namieśnik

  - series: Genotoxicity of selected pharmaceuticals, their binary mixtures, and varying environmental conditions – study with human adenocarcinoma cancer HT29 cell line

  The data set presents the results of cytotoxicity (using theThiazolyl Blue Tetrazolium Bromide (MTT) assay) of oxytetracycline hydrochloride over a range of selected concentrations in a study on human HT29 adenocarcinoma cells.

• Measurement of cytotoxicity using the MTT test of diclofenac sodium salt in a range of selected concen-trations

  Open Research Data

  open access

  • M. Wieczerzak
  • B. Kudłak
  • J. Namieśnik

  - series: Genotoxicity of selected pharmaceuticals, their binary mixtures, and varying environmental conditions – study with human adenocarcinoma cancer HT29 cell line

  The data set presents the results of cytotoxicity (using theThiazolyl Blue Tetrazolium Bromide (MTT) assay) of diclofenac sodium over a range of selected concentrations in a study on human HT29 adenocarcinoma cells.

• Impact of binary mixtures of buthylparaben and β-estradiol on endocrine processes of the model organism Saccharomyces Cerevisiae (using XenoScreen YES/YAS test) - with controls

  Open Research Data

  open access

  • M. Wieczerzak
  • B. Kudłak
  • B. Kudłak

  - series: Ecotoxicological equilibria of triclosan in Microtox, XenoScreen YES/YAS, Caco2, HEPG2 and liposomal systems are affected by the occurrence of other pharmaceutical and personal care emerging contaminants

  Data shown in data set illustrate the results of the endocrine processes of mixtures of methylparaben and  β-estradiol  with controls for YES agonsit, YES antagonist, YAS agonist and YAS antagonist.  S cerevisiae is used as a model organism in the monitoring of endocrine disruptors in environmental and reference samples in Xenometrix® systems - XenoScreen®. ...

• Impact of binary mixtures of diclofenac and β-estradiol on endocrine processes of the model organism Saccharomyces Cerevisiae (using XenoScreen YES/YAS test) - with controls

  Open Research Data

  open access

  • M. Wieczerzak
  • B. Kudłak
  • B. Kudłak

  - series: Ecotoxicological equilibria of triclosan in Microtox, XenoScreen YES/YAS, Caco2, HEPG2 and liposomal systems are affected by the occurrence of other pharmaceutical and personal care emerging contaminants

  Data shown in data set illustrate the results of the endocrine processes of mixtures of methylparaben and  β-estradiol  with controls for YES agonsit, YES antagonist, YAS agonist and YAS antagonist.  S cerevisiae is used as a model organism in the monitoring of endocrine disruptors in environmental and reference samples in Xenometrix® systems - XenoScreen®. ...

• Impact of binary mixtures of 17α-ethinylestradiol and β-estradiol on endocrine processes of the model organism Saccharomyces Cerevisiae (using XenoScreen YES/YAS test) - with controls

  Open Research Data

  open access

  • M. Wieczerzak
  • B. Kudłak
  • B. Kudłak

  - series: Ecotoxicological equilibria of triclosan in Microtox, XenoScreen YES/YAS, Caco2, HEPG2 and liposomal systems are affected by the occurrence of other pharmaceutical and personal care emerging contaminants

  Data shown in data set illustrate the results of the endocrine processes of mixtures of 17α-ethinylestradiol and  β-estradiol  with controls for YES agonsit, YES antagonist, YAS agonist and YAS antagonist.  S cerevisiae is used as a model organism in the monitoring of endocrine disruptors in environmental and reference samples in Xenometrix® systems...

• Impact of binary mixtures of methylparaben and β-estradiol on endocrine processes of the model organism Saccharomyces Cerevisiae (using XenoScreen YES/YAS test) - with controls

  Open Research Data

  open access

  • M. Wieczerzak
  • B. Kudłak
  • B. Kudłak

  - series: Ecotoxicological equilibria of triclosan in Microtox, XenoScreen YES/YAS, Caco2, HEPG2 and liposomal systems are affected by the occurrence of other pharmaceutical and personal care emerging contaminants

  Data shown in data set illustrate the results of the endocrine processes of mixtures of methylparaben and  β-estradiol  with controls for YES agonsit, YES antagonist, YAS agonist and YAS antagonist.  S cerevisiae is used as a model organism in the monitoring of endocrine disruptors in environmental and reference samples in Xenometrix® systems - XenoScreen®. ...

• Impact of binary mixtures of methylparaben and buthylparaben on endocrine processes of the model organism Saccharomyces Cerevisiae (using XenoScreen YES/YAS test) - with controls

  Open Research Data

  open access

  • M. Wieczerzak
  • B. Kudłak
  • B. Kudłak

  - series: Ecotoxicological equilibria of triclosan in Microtox, XenoScreen YES/YAS, Caco2, HEPG2 and liposomal systems are affected by the occurrence of other pharmaceutical and personal care emerging contaminants

  Data shown in data set illustrate the results of the endocrine processes of mixtures of methylparaben  and buthylparaben  with controls for YES agonsit, YES antagonist, YAS agonist and YAS antagonist.  S cerevisiae is used as a model organism in the monitoring of endocrine disruptors in environmental and reference samples in Xenometrix® systems - XenoScreen®....

• Impact of binary mixtures of buthylparaben and 17α-ethinylestradiol on endocrine processes of the model organism Saccharomyces Cerevisiae (using XenoScreen YES/YAS test) - with controls

  Open Research Data

  open access

  • M. Wieczerzak
  • B. Kudłak
  • B. Kudłak

  - series: Ecotoxicological equilibria of triclosan in Microtox, XenoScreen YES/YAS, Caco2, HEPG2 and liposomal systems are affected by the occurrence of other pharmaceutical and personal care emerging contaminants

  Data shown in data set illustrate the results of the endocrine processes of mixtures of buthylparaben and 17α-ethinylestradiol  with controls for YES agonsit, YES antagonist, YAS agonist and YAS antagonist.  S cerevisiae is used as a model organism in the monitoring of endocrine disruptors in environmental and reference samples in Xenometrix® systems...

• Impact of binary mixtures of methylparaben and 17α-ethinylestradiol on endocrine processes of the model organism Saccharomyces Cerevisiae (using XenoScreen YES/YAS test) - with controls

  Open Research Data

  open access

  • M. Wieczerzak
  • B. Kudłak
  • B. Kudłak

  - series: Ecotoxicological equilibria of triclosan in Microtox, XenoScreen YES/YAS, Caco2, HEPG2 and liposomal systems are affected by the occurrence of other pharmaceutical and personal care emerging contaminants

  Data shown in data set illustrate the results of the endocrine processes of mixtures of methylparaben and  β-estradiol  with controls for YES agonsit, YES antagonist, YAS agonist and YAS antagonist.  S cerevisiae is used as a model organism in the monitoring of endocrine disruptors in environmental and reference samples in Xenometrix® systems - XenoScreen®. ...

• Impact of binary mixtures of triclosan and β-estradiol on endocrine processes of the model organism Saccharomyces Cerevisiae (using XenoScreen YES/YAS test) - with controls

  Open Research Data

  open access

  • M. Wieczerzak
  • B. Kudłak
  • B. Kudłak

  - series: Ecotoxicological equilibria of triclosan in Microtox, XenoScreen YES/YAS, Caco2, HEPG2 and liposomal systems are affected by the occurrence of other pharmaceutical and personal care emerging contaminants , Ecotoxicological equilibria of triclosan in Microtox, XenoScreen YES/YAS, Caco2, HEPG2 and liposomal systems are affected by the occurrence of other pharmaceutical and personal care emerging contaminants

  Data shown in data set illustrate the results of the endocrine processes of mixtures of triclosan and  β-estradiol  with controls for YES agonsit, YES antagonist, YAS agonist and YAS antagonist.  S cerevisiae is used as a model organism in the monitoring of endocrine disruptors in environmental and reference samples in Xenometrix® systems - XenoScreen®. ...

• Impact of binary mixtures of triclosan and 17α-ethinylestradiol on endocrine processes of the model organism Saccharomyces Cerevisiae (using XenoScreen YES/YAS test) - with controls

  Open Research Data

  open access

  • M. Wieczerzak
  • B. Kudłak
  • B. Kudłak

  - series: Ecotoxicological equilibria of triclosan in Microtox, XenoScreen YES/YAS, Caco2, HEPG2 and liposomal systems are affected by the occurrence of other pharmaceutical and personal care emerging contaminants , Ecotoxicological equilibria of triclosan in Microtox, XenoScreen YES/YAS, Caco2, HEPG2 and liposomal systems are affected by the occurrence of other pharmaceutical and personal care emerging contaminants

  Data shown in data set illustrate the results of the endocrine processes of mixtures of triclosan and 17α-ethinylestradiol  with controls for YES agonsit, YES antagonist, YAS agonist and YAS antagonist.  S cerevisiae is used as a model organism in the monitoring of endocrine disruptors in environmental and reference samples in Xenometrix® systems -...

• Impact of binary mixtures of diclofenac and buthylparaben of the model organism Saccharomyces Cerevisiae (using XenoScreen YES/YAS test)

  Open Research Data

  open access

  • M. Wieczerzak
  • B. Kudłak
  • B. Kudłak

  - series: Ecotoxicological equilibria of triclosan in Microtox, XenoScreen YES/YAS, Caco2, HEPG2 and liposomal systems are affected by the occurrence of other pharmaceutical and personal care emerging contaminants

  Data shown in data set illustrate the results of the edorin processes of miture of diclofenac and buthylparaben  on S cerevisiae is used as a model organism in the monitoring of endocrine disruptors in environmental and reference samples in Xenometrix® systems - XenoScreen®.  Tested substances have bakeriosis and fungicide properties and are used in...

• Impact of binary mixtures of diclofenac and on endocrine processes of the model organism Saccharomyces Cerevisiae (using XenoScreen YES/YAS test)

  Open Research Data

  open access

  • M. Wieczerzak
  • B. Kudłak
  • B. Kudłak

  - series: Katalog Danych Badawczych - Ecotoxicological equilibria of triclosan in Microtox, XenoScreen YES/YAS, Caco2, HEPG2 and liposomal systems are affected by the occurrence of other pharmaceutical and personal care emerging contaminants

  Data shown in data set highlighte the results of the edorin processes of the diclofenac sodium salt mixture with Methylparaben.  S cerevisiae is used as a model organism in the monitoring of endocrine disruptors in environmental and reference samples in Xenometrix® systems - XenoScreen®.  Methylparaben have  fungicide properties  used in  food preservative,...

• Impact of binary mixtures of Irgasan (triclosan) and Diclofenac on endocrine processes of the model organism Saccharomyces Cerevisiae (using XenoScreen YES/YAS test)

  Open Research Data

  open access

  • M. Wieczerzak
  • B. Kudłak
  • B. Kudłak

  - series: Ecotoxicological equilibria of triclosan in Microtox, XenoScreen YES/YAS, Caco2, HEPG2 and liposomal systems are affected by the occurrence of other pharmaceutical and personal care emerging contaminants

  The XenoScreen YES/YAS reagents and methodology is given in Kudłak et al. (2019) and in details in electronic supplementary material.

• Impact of binary mixtures of Irgasan (triclosan) and two parabens on endocrine processes of the model organism Saccharomyces Cerevisiae (using XenoScreen YES/YAS test)

  Open Research Data

  open access

  • M. Wieczerzak
  • B. Kudłak
  • B. Kudłak

  - series: Ecotoxicological equilibria of triclosan in Microtox, XenoScreen YES/YAS, Caco2, HEPG2 and liposomal systems are affected by the occurrence of other pharmaceutical and personal care emerging contaminants

  Data shown in data set illustrate the results of the edorin processes of the Irgasan (triclosan) mixture with two parabens e.i. methylparaben and buthylparaben.  S cerevisiae is used as a model organism in the monitoring of endocrine disruptors in environmental and reference samples in Xenometrix® systems - XenoScreen®.  Tested substances have bakeriosis...

• Results of pharmaceuticals mixtures toxicity on inhibition of bioluminescence of Vibrio fischeri (Microtox)

  Open Research Data

  open access

  • M. Wieczerzak
  • B. Kudłak
  • J. Namieśnik

  - series: Modeling of pharmaceuticals mixtures toxicity with deviation ratio and best-fit functions models

  The research was concerned with verifying the impact of mixtures of nine pharmaceuticals against a selected organism, i.e., the bacterium Aliivibrio fischeri. A. fisheri is used as a model organism in the monitoring of acute toxicity in environmental and reference samples in Microtox® systems.  Tested pharmaceuticals, namely: diclofenac (sodium salt),...

• Determination of the effective concentration of oxyteracycline solutions on the inhibition of bioluminescence of Vibrio fischeri (Microtox)

  Open Research Data

  open access

  • M. Wieczerzak
  • B. Kudłak
  • J. Namieśnik

  - series: Study of the effect of residues of pharmaceuticals on the environment on the example of bioassay Microtox®

  In this study an attempt was made to determine the effective concentration for oxytetracycline solutions on the  inhibition of bioluminescence of Vibrio fischeri (Microtox). 

• The effect of pH change of oxyteracycline solutions on the on inhibition of bioluminescence of Vibrio fischeri (Microtox)

  Open Research Data

  open access

  • M. Wieczerzak
  • B. Kudłak
  • J. Namieśnik

  - series: Study of the effect of residues of pharmaceuticals on the environment on the example of bioassay Microtox®

  In this study attempt was also made to determine whether a pH change of the sample containing oxyteracycline solutions affects the total toxicity of the sample using the Microtox®

• Impact of binary mixtures of ketoprofen and oxytetracycline on the germination of Sorghum bicolor (sorgo) seeds

  Open Research Data

  open access

  • M. Wieczerzak
  • B. Kudłak
  • J. Namieśnik

  - series: Impact of selected drugs and their binary mixtures on the germination of Sorghum bicolor (sorgo) seeds

  Research was carried out for various ratios of the previously determined EC50 values for mixture of ketoprofen and oxytetracycline the first substance at 100% of its EC50 concentration was mixed with the second substance at 100% of its EC50 concentration, or the first substance at 50% of its EC50 concentration was mixed with the second substance at...

• Impact of binary mixtures of ketoprofen and diclofenac on the germination of Sorghum bicolor (sorgo) seeds

  Open Research Data

  open access

  • M. Wieczerzak
  • B. Kudłak

  - series: Impact of selected drugs and their binary mixtures on the germination of Sorghum bicolor (sorgo) seeds

  Research was carried out for various ratios of the previously determined EC50 values for mixture of ketoprofen and diclofenac, the first substance at 100% of its EC50 concentration was mixed with the second substance at 100% of its EC50 concentration, or the first substance at 50% of its EC50 concentration was mixed with the second substance at 150%...

• Impact of binary mixtures of ketoprofen and chloramphenicol on the germination of Sorghum bicolor (sorgo) seeds

  Open Research Data

  open access

  • M. Wieczerzak
  • B. Kudłak
  • J. Namieśnik

  - series: Impact of selected drugs and their binary mixtures on the germination of Sorghum bicolor (sorgo) seeds

  Research was carried out for various ratios of the previously determined EC50 values for mixture of ketoprofen and chloramphenicol, the first substance at 100% of its EC50 concentration was mixed with the second substance at 100% of its EC50 concentration, or the first substance at 50% of its EC50 concentration was mixed with the second substance at...

• The effect of pH change of ketoprofen solutions on the germination of Sorghum bicolor (sorghum) seeds

  Open Research Data

  open access

  • M. Wieczerzak
  • B. Kudłak
  • J. Namieśnik

  - series: Impact of selected drugs and their binary mixtures on the germination of Sorghum bicolor (sorgo) seeds

  In these studies, an attempt was also made to determine whether (and, if so, to what extent) the change in pH affects the toxicity of ketoprofen will affect the germination of Sorghum bicolor (sorghum) seeds. As reported by Kudlak B, Wieczerzak M, Yotova G, Tsakovski S, Simeonov V, Namieśnik J (2016) Environmental risk assessment of Polish wastewater...

• Determination of the effective concentration of ketoprofen against the germination of Sorghum bicolor (sorghum) seeds

  Open Research Data

  open access

  • M. Wieczerzak
  • B. Kudłak
  • J. Namieśnik

  - series: Impact of selected drugs and their binary mixtures on the germination of Sorghum bicolor (sorgo) seeds

  Research data includes an attempt to determine the effective concentration of ketoprofen that inhibits germination of Sorghum bicolor (sorghum) seeds.

• Results of the effect of mixtures of ketoprofen with three anions on the germination of Sorghum bicolor (sorghum) seeds

  Open Research Data

  open access

  • M. Wieczerzak
  • B. Kudłak
  • J. Namieśnik

  - series: Impact of selected drugs and their binary mixtures on the germination of Sorghum bicolor (sorgo) seeds

  The research data includes an attempt to verify whether the addition of anions (bromide, chloride and fluoride) at levels found in the environment would affect the toxicity of pharmaceuticals to Sorghum Bicolor grain. Ion concentrations were selected based on studies of water samples collected in water bodies receiving wastewater from wastewater treatment...

• Results of the effect of mixtures of ketoprofen with three cations on the germination of Sorghum bicolor (sorghum) seeds

  Open Research Data

  open access

  • M. Wieczerzak
  • B. Kudłak
  • J. Namieśnik

  - series: Impact of selected drugs and their binary mixtures on the germination of Sorghum bicolor (sorgo) seeds

  The research data includes an attempt to verify whether the addition of cations (sodium, ammonium and potassium) at levels found in the environment would affect the toxicity of pharmaceuticals to Sorghum Bicolor grain. Ion concentrations were selected based on studies of water samples collected in water bodies receiving wastewater from wastewater treatment...

• Results of modeling of pharmaceuticals mixtures toxicity with deviation ratio and best-fit functions models using Saccharomyces cerevisiae yeast as model organism

  Open Research Data

  open access

  • M. Wieczerzak
  • B. Kudłak

  - series: Modeling of pharmaceuticals mixtures toxicity with deviation ratio and best-fit functions models

  The research was concerned with verifying the impact of binary mixtures of nine pharmaceuticals against a selected organism, i.e., the yeast Saccharomyces cerevisiae. S cerevisiae is used as a model organism in the monitoring of endocrine disruptors in environmental and reference samples in Xenometrix® systems - XenoScreen®.  Tested pharmaceuticals,...

• Results of modeling of pharmaceuticals mixtures toxicity with deviation ratio and best-fit functions models using Aliivibrio fischeri bacterium as model organism

  Open Research Data

  open access

  • M. Wieczerzak
  • B. Kudłak

  The research was concerned with verifying the impact of mixtures of nine pharmaceuticals against a selected organism, i.e., the bacterium Aliivibrio fischeri. A. fisheri is used as a model organism in the monitoring of acute toxicity in environmental and reference samples in Microtox® systems.  Tested pharmaceuticals, namely: diclofenac (sodium salt),...