Investigation on Filaments for 3D Printing of Nasal Septum Cartilage Implant - Publikacja - MOST Wiedzy

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Investigation on Filaments for 3D Printing of Nasal Septum Cartilage Implant

Abstrakt

Septoplasty is a widely used method in treating deviated septum. Although it is successfully implemented, there are problems with excessive bleeding, septal perforation, or infections. The use of anatomically shaped implants could help overcome these problems. This paper focuses on assessing the possibility of the usage of a nasal septum cartilage implant 3D printed from various market-available filaments. Five different types of laments were used, two of which claim to be suitable for medical use. A combination of modeling, mechanical (bending, compression), structural (FTIR), thermal (DSC, MFR), surface (contact angle), microscopic (optical), degradation (2 M HCl, 5 M NaOH, and 0.01 M PBS), printability, and cell viability (MTT) analyses allowed us to assess the suitability of materials for manufacturing implants. Bioflex had the most applicable properties among the tested materials, but despite the overall good performance, cell viability studies showed toxicity of the material in MTT test. The results of the study show that selected filaments were not suitable for nasal cartilage implants. The poor cell viability of Bioflex could be improved by surface modification. Further research on biocompatible elastic materials for 3D printing is needed either by the synthesis of new materials or by modifying existing ones.

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Informacje szczegółowe

Kategoria:
Publikacja w czasopiśmie
Typ:
artykuły w czasopismach
Opublikowano w:
Materials nr 15,
ISSN: 1996-1944
Język:
angielski
Rok wydania:
2023
Opis bibliograficzny:
Gnatowski P., Gwizdała K., Kurdyn A., Skorek A., Augustin E., Kucińska-Lipka J.: Investigation on Filaments for 3D Printing of Nasal Septum Cartilage Implant// Materials -,iss. 9 (2023), s.3534-
DOI:
Cyfrowy identyfikator dokumentu elektronicznego (otwiera się w nowej karcie) 10.3390/ma16093534
Źródła finansowania:
  • COST_FREE
Weryfikacja:
Politechnika Gdańska

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