Polyurethane Composite Scaffolds Modified with the Mixture of Gelatin and Hydroxyapatite Characterized by Improved Calcium Deposition - Publikacja - MOST Wiedzy

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Polyurethane Composite Scaffolds Modified with the Mixture of Gelatin and Hydroxyapatite Characterized by Improved Calcium Deposition

Abstrakt

The skeleton is a crucial element of the motion system in the human body, whose main function is to support and protect the soft tissues. Furthermore, the elements of the skeleton act as a storage place for minerals and participate in the production of red blood cells. The bone tissue includes the craniomaxillofacial bones, ribs, and spine. There are abundant reports in the literature indicating that the amount of treatments related to bone fractures increases year by year. Nowadays, the regeneration of the bone tissue is performed by using autografts or allografts, but this treatment method possesses a few disadvantages. Therefore, new and promising methods of bone tissue regeneration are constantly being sought. They often include the implantation of tissue scaffolds, which exhibit proper mechanical and osteoconductive properties. In this paper, the preparation of polyurethane (PUR) scaffolds modified by gelatin as the reinforcing factor and hydroxyapatite as the bioactive agent was described. The unmodified and modified scaffolds were tested for their mechanical properties; morphological assessments using optical microscopy were also conducted, as was the ability for calcification using scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDX). Moreover, each type of scaffold was subjected to a degradation process in 5M NaOH and 2M HCl aqueous solutions. It was noticed that the best properties promoting the calcium phosphate deposition were obtained for scaffolds modified with 2% gelatin solution containing 5% of hydroxyapatite

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Kategoria:
Publikacja w czasopiśmie
Typ:
artykuły w czasopismach
Opublikowano w:
Polymers nr 12, strony 1 - 18,
ISSN: 2073-4360
Język:
angielski
Rok wydania:
2020
Opis bibliograficzny:
Carayon I., Szarlej P., Łapiński M., Kucińska-Lipka J.: Polyurethane Composite Scaffolds Modified with the Mixture of Gelatin and Hydroxyapatite Characterized by Improved Calcium Deposition// Polymers -Vol. 12,iss. 2 (2020), s.1-18
DOI:
Cyfrowy identyfikator dokumentu elektronicznego (otwiera się w nowej karcie) 10.3390/polym12020410
Bibliografia: test
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  46. © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). otwiera się w nowej karcie
Źródła finansowania:
  • Politechnika Gdańska nr. projektu 033206
Weryfikacja:
Politechnika Gdańska

wyświetlono 138 razy

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