Prototype of an opto-capacitive probe for non-invasive sensing cerebrospinal fluid circulation - Publikacja - MOST Wiedzy

Wyszukiwarka

Prototype of an opto-capacitive probe for non-invasive sensing cerebrospinal fluid circulation

Abstrakt

In brain studies, the function of the cerebrospinal fluid (CSF) awakes growing interest, particularly related to studies of the glymphatic system in the brain, which is connected with the complex system of lymphatic vessels responsible for cleaning the tissues. The CSF is a clear, colourless liquid including water (H2O) approximately with a concentration of 99 %. In addition, it contains electrolytes, amino acids, glucose, and other small molecules found in plasma. The CSF acts as a cushion behind the skull, providing basic mechanical as well as immunological protection to the brain. Disturbances of the CSF circulation have been linked to several brain related medical disorders, such as dementia. Our goal is to develop an in vivo method for the non-invasive measurement of cerebral blood flow and CSF circulation by exploiting optical and capacitive sensing techniques simultaneously. We introduce a prototype of a wearable probe that is aimed to be used for long-term brain monitoring purposes, especially focusing on studies of the glymphatic system. In this method, changes in cerebral blood flow, particularly oxy- and deoxyhaemoglobin, are measured simultaneously and analysed with the response gathered by the capacitive sensor in order to distinct the dynamics of the CSF circulation behind the skull. Presented prototype probe is tested by measuring liquid flows inside phantoms mimicking the CSF circulation.

Cytowania

  • 0

    CrossRef

  • 0

    Web of Science

  • 0

    Scopus

Autorzy (14)

Cytuj jako

Pełna treść

pobierz publikację
pobrano 41 razy
Wersja publikacji
Accepted albo Published Version
Licencja
Copyright (2017 SPIE)

Słowa kluczowe

Informacje szczegółowe

Kategoria:
Aktywność konferencyjna
Typ:
materiały konferencyjne indeksowane w Web of Science
Tytuł wydania:
Conference on Dynamics and Fluctuations in Biomedical Photonics XIV
Język:
angielski
Rok wydania:
2017
Opis bibliograficzny:
Myllylä T., Vihriälä E., Pedone M., Korhonen V., Surażyński Ł., Wróbel M., Zienkiewicz A., Hakala J., Sorvoja H., Lauri J., Fabritius T., Szczerska M., Kiviniemi V., Meglinski I..: Prototype of an opto-capacitive probe for non-invasive sensing cerebrospinal fluid circulation, W: Conference on Dynamics and Fluctuations in Biomedical Photonics XIV, 2017, ,.
DOI:
Cyfrowy identyfikator dokumentu elektronicznego (otwiera się w nowej karcie) 10.1117/12.2251977
Bibliografia: test
  1. Louveau, Antoine, et al. "Structural and functional features of central nervous system lymphatic vessels." Nature (2015).
  2. Raper, Daniel, Antoine Louveau, and Jonathan Kipnis. "How Do Meningeal Lymphatic Vessels Drain the CNS?." Trends in Neurosciences 39.9 (2016): 581-586. otwiera się w nowej karcie
  3. Kiviniemi, Vesa, et al. "Ultra-fast magnetic resonance encephalography of physiological brain activity- Glymphatic pulsation mechanisms?." Journal of Cerebral Blood Flow & Metabolism (2015): 0271678X15622047. otwiera się w nowej karcie
  4. Ooms, Sharon, et al. "Effect of 1 night of total sleep deprivation on cerebrospinal fluid β-amyloid 42 in healthy middle-aged men: a randomized clinical trial." JAMA neurology 71.8 (2014): 971-977. otwiera się w nowej karcie
  5. Xie, Lulu, et al. "Sleep drives metabolite clearance from the adult brain." science 342.6156 (2013): 373-377. otwiera się w nowej karcie
  6. Spies, Petra E., et al. "Reviewing reasons for the decreased CSF Abeta42 concentration in Alzheimer disease." Front Biosci 17 (2012): 2024-34. otwiera się w nowej karcie
  7. Korhonen, Vesa O., et al. "Light propagation in NIR spectroscopy of the human brain." IEEE Journal of Selected Topics in Quantum Electronics 20.2 (2014): 289-298. otwiera się w nowej karcie
  8. Tuchin, Valery V. "Tissue Optics, Light Scattering Methods and Instruments for Medical Diagnostics." (2015). otwiera się w nowej karcie
  9. Shi, Lingyan, et al. "Transmission in near-infrared optical windows for deep brain imaging." Journal of biophotonics 9.1-2 (2016): 38-43. otwiera się w nowej karcie
  10. Axt, Brant, Song Zhang, and Rajesh Rajamani. "Wearable Coplanar Capacitive Sensor for Measurement of Water Content-A Preliminary Endeavor." Journal of Medical Devices 10.2 (2016): 020953. otwiera się w nowej karcie
  11. Tuchin V.V.,"Tissue Optics: Light Scattering Methods and Instruments for Medical Diagnosis," 3rd ed., PM 166. Bellingham, WA, USA: SPIE Press (2015). otwiera się w nowej karcie
  12. Bhutta, M. R. and Keum-Shik Hong,"Water correction algorithm to increase the signal strength of oxy and deoxy-hemoglobin in near-infrared spectroscopy signals," Industrial Technology (ICIT), 2014 IEEE International Conference on, 589-593 (2014). otwiera się w nowej karcie
  13. Tsuji M., Naruse H., Volpe J. & Holtzman D.,"Reduction of Cytochrome aa3 Measured by Near-Infrared Spectroscopy Predicts Cerebral Energy Loss in Hypoxic Piglets," Pediatr Res 37(3): 253-259 (1995). otwiera się w nowej karcie
  14. Gabriel C., "Compilation of the Dielectric Properties of Body Tissues at RF and Microwave Frequencies," King's College London (United Kingdom), Dept. of Physics (1996). otwiera się w nowej karcie
  15. Wróbel, M. S., Popov, A. P., Bykov, A. V., Tuchin, V. V.., Jędrzejewska-Szczerska, M., "Nanoparticle-free tissue-mimicking phantoms with intrinsic scattering," Biomedical Optics Express 7(6), 2088 (2016). otwiera się w nowej karcie
  16. Feder, I., Wróbel, M., Duadi, H., Jędrzejewska-Szczerska, M., Fixler, D., "Experimental results of full scattering profile from finger tissue-like phantom," Biomedical Optics Express 7(11), 4695-4701 (2016). otwiera się w nowej karcie
  17. Myllylä, T., Korhonen, V., Kiviniemi, V., Tuchin, V, "Experimental studies with selected light sources for NIRS of brain tissue: quantifying tissue chromophore concentration", Proc. SPIE 9305, Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics II, 93051S (March 10, 2015), doi:10.1117/12.2076954. otwiera się w nowej karcie
  18. Wróbel, M. S., Popov, A. P., Bykov, A. V., Kinnunen, M., Jędrzejewska-Szczerska, M., Tuchin, V. V., "Multi- layered tissue head phantoms for noninvasive optical diagnostics," J. Innov. Opt. Health Sci. 8(3), 1541005 (2015). otwiera się w nowej karcie
Weryfikacja:
Politechnika Gdańska

wyświetlono 113 razy

Publikacje, które mogą cię zainteresować

Meta Tagi