Year 2025

• Nanoparticle Skin Penetration: Depths and Routes Modeled In-Silico

  Publication

  • N. Maeda
  • H. Jiao
  • I. E. Kłosowska-Chomiczewska (formerly: I. Kłosowska-Chomiczewska)
  • W. Artichowicz
  • U. Preiss
  • P. Szumała
  • A. Macierzanka
  • C. Jungnickel

  - SMALL - Year 2025

  Nanoparticles (NPs) are increasingly explored for targeted skin penetration, particularly for pharmaceutical and cosmetic applications. However, the complex system between NP properties, skin structure, and experimental conditions poses significant challenges in predicting their penetration depth and pathways. To what depth do NPs penetrate the skin, and which pathways do they follow? These are the questions we tried to answer...

  Full text available to download

Year 2022

• Analysis of the Factors Affecting Static In Vitro Pepsinolysis of Food Proteins

  Publication

  • N. Maeda
  • D. Marcinkowska (formerly: D. Dulko)
  • A. Macierzanka
  • C. Jungnickel

  - MOLECULES - Year 2022

  In this meta-analysis, we collected 58 publications spanning the last seven decades that reported static in vitro protein gastric digestion results. A number of descriptors of the pepsinolysis process were extracted, including protein type; pepsin activity and concentration; protein concentration; pH; additives; protein form (e.g., ‘native’, ‘emulsion’, ‘gel’, etc.); molecular weight of the protein; treatment; temperature; and...

  Full text available to download