Olga Siewruk - Publications - Bridge of Knowledge

Olga Siewruk

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Year 2014

Electrochemical simulation of enzymatic transformations studied for the selected antitumor acridine derivatives
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- Year 2014
The elucidation of the metabolic pathways and the biotransformation mechanisms of potential drugs is a crucial point in drug development. It allows to know the activation routes of the new biologically active compounds, especially in respect to their possible toxicity. Generally, in vivo or in vitro experiments with liver microsomes or hepatocytes are performed. However, these testing schemes are tedious, time consuming and of...

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