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Bioactive and bioavailability of minerals in rats loaded with cholesterol and kiwi fruit

Abstract

The aim of this study was to compare the content of polyphenols (TP), minerals, ascorbic acid (AA) and total antioxidant capacities (TAC) of conventional and organic kiwifruit ‘Hayward’ treated with ethylene after harvest and to determine their influence on plasma TAC, mineral content in the liver and bioavailability (RBV — relative bioavailability value) in rats fed diet containing cholesterol. Organic and conventionally grown kiwifruits ‘Hayward’ as supplementation to rat diet were investigated in vitro for their bioactive compounds (polyphenols, flavonoids, flavanols, tannins, dietary fiber, and ascorbic acid), minerals, trace elements and TAC. In the in vivo investigation, 36 male Wistar rats (111 ± 5 g) were randomly divided into six diet groups, each of 6 rats: control without cholesterol (C) and 5 groups with 1% cholesterol (ch). Four cholesterol groups were supplemented with 5% lyophilized kiwifruit: ethylene treated, organic (chOHE) or conventional (chCHE) and untreated, and organic (chOHC) or conventional (chCHC). During a period of 33 days of ad libitum feeding feed intake, body weight and feed utilization ration (FER) were controlled. In the end of the experiment rats were anesthetized using Narcotan and sacrificed, and blood and liver were assessed. Testing of antioxidant activity in plasma, minerals and trace elements in the diet and in the liver was performed. Ethylene-treated organic kiwifruit (OHE) had the highest content of TP and TAC. Mg content was significantly higher and Mn was lower in organic kiwifruit ‘Hayward’.

Authors (9)

  • Photo of  Maria Leontowicz

    Maria Leontowicz

    • Warsaw University of Life Sciences Faculty of Veterinary Medicine
  • Photo of  Iwona Jesion

    Iwona Jesion

    • Warsaw University of Life Sciences Faculty of Veterinary Medicine
  • Photo of  Hanna Leontowicz

    Hanna Leontowicz

    • Warsaw University of Life Sciences Faculty of Veterinary Medicine
  • Photo of  Yong Seo Park

    Yong Seo Park

    • Department of Horticultural Science Mopko National University
  • Photo of  Zenon Jastrzebski

    Zenon Jastrzebski

    • National Medicine Institute Warsaw, Poland
  • Photo of  Elena Katrich

    Elena Katrich

    • The institue for Drug Research School of Pharmacy
  • Photo of  Zev Tashma

    Zev Tashma

    • The Institute for Drug Research School of Pharmacy
  • Photo of  Shela Gorinstein

    Shela Gorinstein

    • The Institute for Drug Research School of Pharmacy

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Category:
Articles
Type:
artykuł w czasopiśmie wyróżnionym w JCR
Published in:
MICROCHEMICAL JOURNAL no. 114, pages 148 - 154,
ISSN: 0026-265X
Language:
English
Publication year:
2014
Bibliographic description:
Leontowicz M., Jesion I., Leontowicz H., Park Y., Namieśnik J., Jastrzebski Z., Katrich E., Tashma Z., Gorinstein S.: Bioactive and bioavailability of minerals in rats loaded with cholesterol and kiwi fruit// MICROCHEMICAL JOURNAL. -Vol. 114, (2014), s.148-154
Verified by:
Gdańsk University of Technology

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