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Biological properties of chitosan/Eudragit E 100 and chitosan/poly(4-vinylpyridine) coatings electrophoretically deposited on AgNPs-decorated titanium substrate
Abstract
The objective of the study was the determination of the response, in contact with human osteoblast-like MG-63 cells, of electrophoretically deposited coatings composed of chitosan (CS), Eudragit E 100 (EE100), or poly(4- vinylpyridine) (P4VP) on a silver nanoparticle (AgNPs)-decorated titanium substrate. Before deposition, the substrate was coated with silver by electro-reduction of silver nitrate. The coatings deposition was carried out in suspensions containing 0.1 % (w/w) of one of the biopolymers, EE100 or P4VP, with 0.1 % (w/w) of CS for 10 V and 1 min. Biopolymer coatings were successfully deposited while maintaining high uniformity. The deposited silver did not cause cytotoxicity. The biological study revealed that when compared to CS/P4VP, CS/EE100 coating performed better and showed a decrease in MG-63 cell viability only after three days of testing.
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Authors (4)
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Muhammad Asim Akhtar
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Aldo R. Boccaccini
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- Category:
- Articles
- Type:
- artykuły w czasopismach
- Published in:
-
MATERIALS LETTERS
no. 336,
ISSN: 0167-577X - Language:
- English
- Publication year:
- 2023
- Bibliographic description:
- Pawłowski Ł., Asim Akhtar M., Zieliński A., Boccaccini A. R.: Biological properties of chitosan/Eudragit E 100 and chitosan/poly(4-vinylpyridine) coatings electrophoretically deposited on AgNPs-decorated titanium substrate// MATERIALS LETTERS -Vol. 336, (2023), s.133885-
- DOI:
- Digital Object Identifier (open in new tab) 10.1016/j.matlet.2023.133885
- Sources of funding:
-
- COST_FREE
- Verified by:
- Gdańsk University of Technology
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