Boron-doped carbon nanowalls as effective electrodes for non-enzymatic electrochemical glucose detection: A novel bimodal EC-SALDI-MS approach - Publication - Bridge of Knowledge

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Boron-doped carbon nanowalls as effective electrodes for non-enzymatic electrochemical glucose detection: A novel bimodal EC-SALDI-MS approach

Abstract

For the first time, boron-doped carbon nanowalls (B-CNWs) have been used as effective working electrodes for non-enzymatic electrochemical glucose detection. To achieve optimal response time and sensitivity, we activated B-CNWs by polarising them at 1.1 V in NaOH for 60 min. We established a robust linear dynamic range for glucose concentrations from 10 to 550 μM and calculated a limit of detection (LoD) of 10 μM. Additionally, B-CNWs demonstrated excellent selectivity for glucose, even in the presence of various interfering compounds like its isomer, galactose. Importantly, we showed that B-CNWs could detect gluconic acid, the oxidation product of glucose, using mass spectrometry in an off-line configuration. This novel approach combines electrochemical (EC) and surface-assisted laser desorption/ionisation mass spectrometry (SALDI-MS) detection, utilising the same nanomaterial (B-CNWs) in a bimodal configuration. This coupling represents a significant advancement in glucose sensing technology by leveraging the unique properties of B-CNWs and providing a powerful analytical tool for detecting, identifying, and understanding a wide range of chemical compounds and processes.

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Category:
Articles
Type:
artykuły w czasopismach dostępnych w wersji elektronicznej [także online]
Published in:
Materials Today Nano
ISSN:
Language:
English
Publication year:
2025
Bibliographic description:
Hosu I., Sobaszek M., Bogdanowicz R., Ficek M., Coffinier Y., Boron-doped carbon nanowalls as effective electrodes for non-enzymatic electrochemical glucose detection: A novel bimodal EC-SALDI-MS approach, Materials Today Nano,2025, ,10.1016/j.mtnano.2025.100635
DOI:
Digital Object Identifier (open in new tab) 10.1016/j.mtnano.2025.100635
Sources of funding:
  • Free publication
Verified by:
Gdańsk University of Technology

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