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Determination of thiocyanate as a biomarker of tobacco smoke constituents in selected biological materials of human origin
Abstract
n order to protect human health, it is necessary to biomonitor toxic substances originating from tobacco smoke in biological materials sampled from persons with different exposures to tobacco smoke constituents. Thiocyanate anion is a biomarker of exposure to tobacco smoke components which is characterized by a relatively long half‐life in the human body, i.e. 6 days. In this work, we present the results of thiocyanate determinations performed on samples of placenta, meconium, saliva, breast milk, sweat and blood. The placenta samples were subjected to accelerated solvent extraction with water. The thiocyanate concentrations were determined using ion chromatogra- phy. The analyzed biological materials were compared with regard to their applicability for biomon- itoring toxic substances originating from tobacco smoke. The highest mean concentrations of thiocyanate were observed in the samples of biological materials collected from active smokers.
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Authors (6)
-
Bogumiła Kiełbratowska dr
- Department of Obsterics Medical University of Gdańsk
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Alicja Kotłowska
- Department of Bromatology Medical University of Gdańsk
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Keywords
Details
- Category:
- Articles
- Type:
- artykuł w czasopiśmie wyróżnionym w JCR
- Published in:
-
BIOMEDICAL CHROMATOGRAPHY
no. 32,
pages 1 - 8,
ISSN: 0269-3879 - Language:
- English
- Publication year:
- 2018
- Bibliographic description:
- Narkowicz S., Jaszczak-Wilke E., Polkowska Ż., Kiełbratowska B., Kotłowska A., Namieśnik J.: Determination of thiocyanate as a biomarker of tobacco smoke constituents in selected biological materials of human origin// BIOMEDICAL CHROMATOGRAPHY. -Vol. 32, iss. 3 (2018), s.1-8
- DOI:
- Digital Object Identifier (open in new tab) 10.1002/bmc.4111
- Verified by:
- Gdańsk University of Technology
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