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Impact of temperature on optical sensing in biology based on investigation of SARS‐CoV ‐2

Abstract

In this paper, we present an investigation of the influence of the temperature on the sensing of biological samples. We used biofunctionalized microsphere-based fiber-optic sensor to detect immunoglobulin G attached to the sensor head at temperatures relevant in biological research: 5°C, 25°C, and 55°C. The construction of the sensor allowed us to perform measurements in the small amount of solution. The results of our experiment confirm substantial changes in the measured reflected optical power, indicating the need to control the temperature during such measurements. The sensitivity of the sensor used in this research is 8.82 nW/°C. Coefficient R was also calculated and it equals 0.998, which shows good fit between theoretical linear fit and obtained measured data.

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DOI:
Digital Object Identifier (open in new tab) 10.1002/jbio.202200186
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Copyright (2022 John Wiley & Sons, Inc.)

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Category:
Articles
Type:
artykuły w czasopismach
Published in:
Journal of Biophotonics no. 16,
ISSN: 1864-063X
Language:
English
Publication year:
2023
Bibliographic description:
Szczerska M., Wityk P., Listewnik P.: Impact of temperature on optical sensing in biology based on investigation of SARS‐CoV ‐2// Journal of Biophotonics -Vol. 16,iss. 1 (2023),
DOI:
Digital Object Identifier (open in new tab) 10.1002/jbio.202200186
Verified by:
Gdańsk University of Technology

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