In Vitro Biological Characterization of Silver-Doped Anodic Oxide Coating on Titanium - Publication - Bridge of Knowledge

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In Vitro Biological Characterization of Silver-Doped Anodic Oxide Coating on Titanium

Abstract

Despite the high biocompatibility and clinical effectiveness of Ti-based implants, surface functionalization (with complex osteointegrative/antibacterial strategies) is still required. To enhance the dental implant surface and to provide additional osteoinductive and antibacterial properties, plasma electrolytic oxidation of a pure Ti was performed using a nitrilotriacetic acid (NTA)-based Ag nanoparticles (AgNP)-loaded calcium–phosphate solution. Chemical and structural properties of the surface-modified titanium were assessed using scanning electron microscopy (SEM) with energy dispersive X-ray (EDX) and contact angle measurement. A bacterial adhesion test and cell culture biocompatibility with collagen production were performed to evaluate biological effectiveness of the Ti after the plasma electrolytic process. The NTA-based calcium– phosphate solution with Ag nanoparticles (AgNPs) can provide formation of a thick, porous plasma electrolytic oxidation (PEO) layer enriched in silver oxide. Voltage elevation leads to increased porosity and a hydrophilic nature of the newly formed ceramic coating. The silver-enriched PEO layer exhibits an effective antibacterial effect with high biocompatibility and increased collagen production that could be an effective complex strategy for dental and orthopedic implant development.

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Category:
Articles
Type:
artykuły w czasopismach
Published in:
Materials no. 13,
ISSN: 1996-1944
Language:
English
Publication year:
2020
Bibliographic description:
Oleshko O., Liubchak I., Husak Y., Korniienko V., Yusupova A., Oleshko T., Banasiuk R., Szkodo M., Taranets I., Kazek-Kęsik A., Simka W., Pogorielov M.: In Vitro Biological Characterization of Silver-Doped Anodic Oxide Coating on Titanium// Materials -Vol. 13,iss. 19 (2020), s.4359-
DOI:
Digital Object Identifier (open in new tab) 10.3390/ma13194359
Verified by:
Gdańsk University of Technology

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