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Recurrent bowel-blood translocations of Escherichia coli with the unique virulence characteristics over three-year period in the patient with acute myeloid leukaemia – case report
Abstract
In patients with haematological malignancies, the bowel remains the main source of Escherichia coli bloodstream infections. We present the clinical example of recurrent bowel-blood translocations of E. coli with the unique virulence characteristics in a 55-year-old male with the diagnosis of acute myeloid leukaemia. The virulent factors profile of examined strains confirmed that the co-existence of genes papC, sfa, usp and cnf1, encoding virulence factors, predisposes E. coli to translocation from the gastrointestinal tract to the vascular bed. The close cooperation between haematologists and microbiologists is essential to improve the outcome of patients colonised with highly pathogenic strains.
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Authors (5)
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Anna Śledzińska
- Katedra Monitoringu Terapii i Farmakogenetyki Gdański Uniwersytet Medyczny
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Agnieszka Piekarska
- Katedra Hematologii i Transplantologii Gdański Uniwersytet Medyczny
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Andrzej Hellmann Dr n. med.
- Katedra Hematologii i Transplantologii
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- DOI:
- Digital Object Identifier (open in new tab) 10.1007/s13353-017-0393-6
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Details
- Category:
- Articles
- Type:
- artykuł w czasopiśmie wyróżnionym w JCR
- Published in:
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JOURNAL OF APPLIED GENETICS
no. 58,
edition 3,
pages 415 - 418,
ISSN: 1234-1983 - Language:
- English
- Publication year:
- 2017
- Bibliographic description:
- Krawczyk B., Śledzińska A., Piekarska A., Hellmann A., Kur J.: Recurrent bowel-blood translocations of Escherichia coli with the unique virulence characteristics over three-year period in the patient with acute myeloid leukaemia – case report// JOURNAL OF APPLIED GENETICS. -Vol. 58, iss. 3 (2017), s.415-418
- DOI:
- Digital Object Identifier (open in new tab) 10.1007/s13353-017-0393-6
- Verified by:
- Gdańsk University of Technology
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