Search results for: Microglia

• Nitric Oxide-Dependent Pathways as Critical Factors in the Consequences and Recovery after Brain Ischemic Hypoxia

  Publication

  • J. M. Wierońska
  • P. Cieślik
  • L. Kalinowski

  - Biomolecules - Year 2021

  Brain ischemia is one of the leading causes of disability and mortality worldwide. Nitric oxide (NO), a molecule that is involved in the regulation of proper blood flow, vasodilation, neuronal and glial activity constitutes the crucial factor that contributes to the development of pathological changes after stroke. One of the early consequences of a sudden interruption in the cerebral blood flow is the massive production of reactive...

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• Growth inhibition of cultured cancer cells by Ribes nigrum leaf extract

  Publication

  • M. Ginovyan
  • A. Bartoszek-Pączkowska
  • I. Koss-Mikołajczyk
  • B. Kusznierewicz
  • P. Andreoletti
  • M. Cherkaoui-malki
  • N. Sahakyan

  - AIMS Biophysics - Year 2022

  The present article includes data on the possible selective cytotoxic effect of extract of Ribes nigrum L. growing at high Armenian landscape. For this purpose, different non-cancer (microglial BV-2 wild type (Wt), acyl-CoA oxidase 1 (ACOX1) deficient (Acox1-/-) and cancer (human colon adenocarcinoma HT29 and human breast cancer MCF7) cell lines were applied. R. nigrum leaf ethanol extract showed a growth inhibition effect towards...

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