Search results for: COLON

• Neuroendocrine tumor, grade 2 - Female, 39 - Tissue image [6060730023673481]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Neuroendocrine tumor, grade 2 - Female, 39 - Tissue image [6060730023679281]

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  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Adenocarcinoma, NOS - Female, 62 - Tissue image [9070730015336691]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Adenocarcinoma, NOS - Female, 61 - Tissue image [6060730023686731]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Adenocarcinoma, NOS - Female, 62 - Tissue image [9070730015335461]

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  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Tubular adenocarcinoma - Unknown, 84 - Tissue image [330073006939981]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Malignant neoplasm of unspecified ovary - Female, 66 - Tissue image [9020730024814211]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Adenocarcinoma, usual type - Male, 55 - Tissue image [7040247104946181]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Adenocarcinoma, usual type - Male, 55 - Tissue image [5310730015839711]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Diverticular disease of both small and large intestine with perforation and abscess - Female, 79 - Tissue image [9070730015337501]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Adenocarcinoma, usual type - Male, 55 - Tissue image [5310730015833241]

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  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Tubular adenocarcinoma - Unknown, 84 - Tissue image [3300730069395061]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Adenocarcinoma, intestinal type - Female, 71 - Tissue image [5310730015836351]

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  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Adenocarcinoma, intestinal type - Female, 71 - Tissue image [5310730015837611]

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  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• GIST - Female, 78 - Tissue image [5040730020286791]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Adenocarcinoma, intestinal type - Female, 71 - Tissue image [5310730015832761]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• GIST - Female, 78 - Tissue image [504073002028571]

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  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• GIST - Female, 78 - Tissue image [5040730020286821]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Adenocarcinoma, intestinal type - Female, 71 - Tissue image [5310730015834161]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• The impact of interactions between polyphenolic antioxidants on the redox-related chemical and biological properties of their mixtures – the extension of food synergy concept.

  Publication

  • M. Baranowska

  - Year 2022

  The results of studies indicate that chemopreventive efficiency of isolated phytochemicals is lower than that of polyphenol-rich foods. This discrepancy has been ascribed to the food synergy concept that assumes additive or even synergistic influence of different food ingredients on human health. The results presented in the dissertation made it possible to propose an alternative and innovative explanation of these observations. The...

• Tetrahydroquinolinone derivatives exert antiproliferative effect on lung cancer cells through apoptosis induction

  Publication

  • M. Ryczkowska
  • N. Maciejewska
  • M. Olszewski
  • M. Witkowska
  • S. Makowiec

  - Scientific Reports - Year 2022

  The anticancer properties of quinolones is a topic of interest among researchers in the scientific world. Because these compounds do not cause side effects, unlike the commonly used cytostatics, they are considered a promising source of new anticancer drugs. In this work, we designed a brief synthetic pathway and obtained a series of novel 8-phenyltetrahydroquinolinone derivatives functionalized with benzyl-type moieties at position...

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• Growth inhibition of cultured cancer cells by Ribes nigrum leaf extract

  Publication

  • M. Ginovyan
  • A. Bartoszek-Pączkowska
  • I. Koss-Mikołajczyk
  • B. Kusznierewicz
  • P. Andreoletti
  • M. Cherkaoui-malki
  • N. Sahakyan

  - AIMS Biophysics - Year 2022

  The present article includes data on the possible selective cytotoxic effect of extract of Ribes nigrum L. growing at high Armenian landscape. For this purpose, different non-cancer (microglial BV-2 wild type (Wt), acyl-CoA oxidase 1 (ACOX1) deficient (Acox1-/-) and cancer (human colon adenocarcinoma HT29 and human breast cancer MCF7) cell lines were applied. R. nigrum leaf ethanol extract showed a growth inhibition effect towards...

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• Utilizing Genome-Wide mRNA Profiling to Identify the Cytotoxic Chemotherapeutic Mechanism of Triazoloacridone C-1305 as Direct Microtubule Stabilization

  Publication

  • J. Króliczewski,
  • S. Bartoszewska
  • M. Dudkowska
  • D. Janiszewska
  • A. Biernatowska
  • D. Crossman
  • K. Krzymiński
  • M. Wysocka
  • A. Romanowska
  • M. Bagiński... and 6 others

  - Cancers - Year 2020

  Rational drug design and in vitro pharmacology profiling constitute the gold standard in drug development pipelines. Problems arise, however, because this process is often dicult due to limited information regarding the complete identification of a molecule’s biological activities. The increasing aordability of genome-wide next-generation technologies now provides an excellent opportunity to understand a compound’s diverse eects...

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• GIST - Female, 78 - Tissue image [5040730020288961]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• GIST - Female, 78 - Tissue image [5040730020284111]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Antitumor 1-nitroacridine derivative C-1748 induces significant apoptosis in pancreatic cancer cells.

  Publication

  • B. Borowa-Mazgaj
  • E. Augustin
  • Z. Mazerska
  • J. Konopa

  - Acta Biochimica Polonica - Year 2014

  Pancreatic cancer is the fifth leading cause of cancer death and has the lowest survival rate of any solid cancer in the industrial countries. The poor prognosis of pancreatic cancer results from its tendency for late presentation, aggressive invasion, early metastasis, and resistance to chemotherapy. Gemcitabine still remains the best chemotherapeutic agent available for the treatment of advanced pancreatic cancer. However, gemcitabine...

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• Novel approaches in the synthesis of batracylin and its analogs: rebirth of an old player?

  Publication

  • K. Dzierzbicka
  • W. Januchta
  • A. Składanowski

  - CURRENT MEDICINAL CHEMISTRY - Year 2012

  W pracy opisano batracylinę (BAT), jej syntezę i aktywność biologiczną oraz otrzymane analogi. BAT została wyselekcjonowana przez NCI (Bethesda, USA) w programie poszukiwań nowych potencjalnych leków przeciwnowotworowych. Związek ten w badaniach in vivo na myszach okazał się bardzo aktywny przeciw nowotworowi okrężnicy 38 (Colon 38), trudnemu do wyleczenia przez dotychczas znane leki przeciwnowotworowe. Jest ona skuteczna również...

• A strong preference for the TA/TA dinucleotide step discovered for an acridine-based, potent antitumor dsDNA intercalator, C-1305: NMR-driven structural and sequence-specificity studies

  Publication

  • T. Laskowski
  • W. Andrałojć
  • J. Grynda
  • P. Gwarda
  • J. Mazerski
  • Z. Gdaniec

  - Scientific Reports - Year 2020

  Triazoloacridinone C-1305, a potent antitumor agent recommended for Phase I clinical trials, exhibits high activity towards a wide range of experimental colon carcinomas, in many cases associated with complete tumor regression. C-1305 is a well-established dsDNA intercalator, yet no information on its mode of binding into DNA is available to date. Herein, we present the NMR-driven and MD-refined reconstruction of the 3D structures...

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• Synthesis, molecular structure, and metabolic stability of new series of N' -(2-alkylthio-4-chloro-5-methylbenzenesulfonyl)-1-(5-phenyl-1 H -pyrazol-1-yl)amidine as potential anti-cancer agents

  Publication

  • A. Pogorzelska
  • J. Sławiński
  • A. Kawiak
  • B. Żołnowska
  • J. Chojnacki
  • G. Stasiłojć
  • S. Ulenberg
  • K. Szafrański
  • T. Bączek

  - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - Year 2018

  A series of new N'-(2-alkylthio-4-chloro-5-methylbenzenesulfonyl)-1-(5-phenyl-1H-pyrazol-1-yl)amidine derivatives have been synthesized and evaluated in vitro by MTT assays for their antiproliferative activity against cell lines of colon cancer HCT-116, cervical cancer HeLa and breast cancer MCF-7. The studied compounds display selective activity mainly against HCT-116 and HeLa cells. Thus, five compounds show selective cytotoxic...

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• Adenocarcinoma, NOS - Female, 86 - Tissue image [6060730023683541]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Adenocarcinoma in adenomatous polyp - Female, 61 - Tissue image [6290730011497991]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Adenocarcinoma, intestinal type - Male, 51 - Tissue image [4080730008361251]

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  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Adenocarcinoma, NOS - Male, 76 - Tissue image [6210730043063561]

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  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Tubular adenocarcinoma - Unknown, 67 - Tissue image [3300730069387171]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Adenocarcinoma, NOS - Female, 67 - Tissue image [10110730048212801]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Adenocarcinoma, NOS - Female, 62 - Tissue image [9070730015333431]

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  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Adenocarcinoma, intestinal type - Female, 71 - Tissue image [5310730015833461]

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  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Adenocarcinoma, intestinal type - Female, 71 - Tissue image [5310730015835091]

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  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Tubular adenocarcinoma - Unknown, 67 - Tissue image [3300730069381171]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Tubular adenocarcinoma - Unknown, 67 - Tissue image [3300730069381061]

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  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Mucinous adenocarcinoma - Male, 65 - Tissue image [7010730010784401]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Crohn's disease, unspecified - Female, 27 - Tissue image [8200729592217361]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Tubular adenocarcinoma - Unknown, 67 - Tissue image [3300730069396311]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Crohn's disease, unspecified - Female, 27 - Tissue image [8200729592219571]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Tubular adenocarcinoma - Unknown, 67 - Tissue image [3300730069392751]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Crohn's disease, unspecified - Female, 27 - Tissue image [8200729592219901]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Crohn's disease, unspecified - Female, 27 - Tissue image [8200729592219351]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Polyp of stomach and duodenum - Male, 50 - Tissue image [8160730027015891]

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  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Crohn's disease, unspecified - Female, 27 - Tissue image [8200729592219691]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Mucinous adenocarcinoma - Male, 65 - Tissue image [7010730010788241]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.