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Search results for: drug screening platform
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Intercalation complex of imidazoacridinone C-1311, a potential anticancer drug, with DNA helix d(CGATCG)2: stereostructural studies by 2D NMR spectroscopy.
PublicationImidazoacridinone C-1311 (Symadex®) is a powerful antitumor agent, which successfully made its way through the Phase I clinical trials and has been recommended for Phase II few a years ago. It has been shown experimentally that during the initial stage of its action C-1311 forms a relatively stable intercalation complex with DNA, yet it has shown no base-sequence specificity while binding to DNA. In this paper, the d(CGATCG)2:C-1311...
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Performance of various risk prediction models in a large lung cancer screening cohort in Gdańsk, Poland—a comparative study
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Cut-off points for Polish-language versions of depression screening tools among patients with Type 2 diabetes
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Analyzing and Visualizing Uncertain Knowledge: The Use of TEI Annotations in the PROVIDEDH Open Science Platform
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Self-assembled epitaxial BiFeO3 nanostructures as a tailored platform for vertically aligned nanocomposites development
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Non-enzymatic flexible glucose sensing platform based on nanostructured TiO2–Au composite
PublicationAll over the world the number of people suffering from diabetes and related complications is drastically growing. Therefore, the need for accurate, reliable and stable sensor for monitoring of glucose in human body fluids is becoming highly desirable. In this work we show that material composed of gold layers deposited onto TiO2 nanotubes (NTs) formed onto the flexible Ti foil exhibits great response toward glucose oxidation and...
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METHOD TO EXTEND OPERATIONABILITY OF WEB-GIS BASED MARINE SERVICES USING SSE PLATFORM
PublicationEarth Observation (EO) products are widely used by geospatial society. Over the last years a number of new applications of satellite imagery were proposed. This led to an increased interest in EO products, not only from researchers but also from companies and individuals. The authors constitute the essential part of the team that created the marine, web-GIS system - SafeCity GIS - for dissemination of data obtained from a 1.5...
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Bioactive silica-based drug delivery systems containing doxorubicin hydrochloride: In vitro studies
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Use of Materials Based on Polymeric Silica as Bone-Targeted Drug Delivery Systems for Metronidazole
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Drug transporter expression profiling in chemoresistant variants of the A2780 ovarian cancer cell line
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Microneedle‐Based Generation of Microbubbles in Cancer Tumors to Improve Ultrasound‐Assisted Drug Delivery
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Silver Nanoparticles as Chlorhexidine and Metronidazole Drug Delivery Platforms: Their Potential Use in Treating Periodontitis
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Drug-Releasing Antibacterial Coating Made from Nano-Hydroxyapatite Using the Sonocoating Method
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The modulatory effect of green tea catechin on drug resistance in human ovarian cancer cells
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Acinetobacter baumannii isolated from hospital‐acquired infection: biofilm production and drug susceptibility
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Fulminant hepatic failure in woman with iron and non-steroidal anti-inflammatory drug intoxication
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Cisplatin filled multiwalled carbon nanotubes – a novel molecular hybrid of anticancer drug container
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Homoisocitrate dehydrogenase from Candida albicans: properties, inhibition, and targeting by an antifungal pro-drug
PublicationThe LYS12 gene from Candida albicans, coding for homoisocitrate dehydrogenase was cloned and expressed as a His-tagged protein in Escherichia coli. The purified gene product catalyzes the Mg2+- and K+-dependent oxidative decarboxylation of homoisocitrate to alpha-ketoadipate. The recombinant enzyme demonstrates strict specificity for homoisocitrate. SDS-PAGE of CaHIcDH revealed its molecular mass of 42.6±1 kDa, while in size-exclusion...
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Glucosamine-6-phosphate synthase,a novel target for antifungalagents.Molecular modelling studies in drug design
PublicationPraca dotyczy modelowania zarówno samych inhibitorów syntazy glukozamino-6-fosforanu jak i ich oddziaływania z obydwiema domenami tego enzymu. Enzym syntaza glukozamino-6-fosforanu został zaproponowany jako nowy cel molekularny w chemoterapii infekcji grzybowych. Zaprojektowano i zsyntezowano szereg inhibitorów tego enzymu - potencjalnych nowych leków przeciwgrzybowych. Dzięki modelowaniu molekularnemu udało się wyjaśnić mechanizm...
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DRUG AND CHEMICAL TOXICOLOGY
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DRUG METABOLISM AND DISPOSITION
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DRUG DEVELOPMENT RESEARCH
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DRUG DISCOVERY TODAY
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DRUG METABOLISM REVIEWS
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ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES
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ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH
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Expert Opinion On Drug Safety
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American Health and Drug Benefits
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Drug Delivery and Translational Research
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Expert Opinion on Drug Delivery
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Journal of Drug Metabolism & Toxicology
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International Journal of Drug Discovery
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Expert Opinion on Drug Discovery
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FOOD AND DRUG LAW JOURNAL
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Drug Healthcare and Patient Safety
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Clinical Pharmacology in Drug Development
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INTERNATIONAL JOURNAL OF DRUG POLICY
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Journal of Drug Policy Analysis
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Current drug abuse reviews
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Infectious Disorders - Drug Targets
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Journal of Nanopharmaceutics and Drug Delivery
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Drug Discovery Today: Technologies
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Therapeutic Advances in Drug Safety
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Adverse Drug Reaction Bulletin
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Current Drug Discovery Technologies
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Drug Safety - Case Reports
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Journal of Alcohol and Drug Education
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Journal of Drug and Alcohol Research
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Drug Metabolism and Personalized Therapy
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Adverse Drug Reactions Journal
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