Filters
total: 2948
displaying 1000 best results Help
Search results for: molecular umbrella
-
Interaction of amphotericin B with phospholipids in the model membrane - molecular dynamics study.
PublicationAmfoterycyna B jest antybiotykiem używanym w leczeniu układowych infekcji grzybowych. Jej mechanizm działania polega na tworzeniu kanałów wewnątrz błon lipidowych. W przedstawianej pracy publikowane są wyniki symulacji przeprowadzonej dynamiką molekularną monomerycznej i dimerycznej formy antybiotyku wewnątrz błony lipidowej zbudowanej z cząsteczek DMPC. Wyniki te wskazują, że powinowactwo cząsteczek amfoterycyny wewnątrz dimeru...
-
Hydration of N-Hydroxyurea from Ab Initio Molecular Dynamics Simulations
PublicationN-Hydroxyurea (HU) is an important chemotherapeutic agent used as a first-line treatment in conditions such as sickle cell disease and β-thalassemia, among others. To date, its properties as a hydrated molecule in the blood plasma or cytoplasm are dramatically understudied, although they may be crucial to the binding of HU to the radical catalytic site of ribonucleotide reductase, its molecular target. The purpose of this work...
-
Transport deficiency is the molecular basis of Candida albicans resistance to antifungal oligopeptides
Publication(FMDP), an inhibitor of glucosamine-6-phosphate synthase, exhibited growth inhibitory activity against Candida albicans, with minimal inhibitory concentration values in the 0.05–50 mg/L range. Uptake by the peptide permeases was found to be the main factor limiting an anticandidal activity of these compounds. Di- and tripeptide containing FMDP (F2 and F3) were transported by Ptr2p/Ptr22p peptide transporters (PTR) and FMDP-containing...
-
Low-Molecular Pyrazine-Based DNA Binders: Physicochemical and Antimicrobial Properties
PublicationPyrazine and its derivatives are a large group of compounds that exhibit broad biological activity, the changes of which can be easily detected by a substituent effect or a change in the functional group. The present studies combined theoretical research with the density functional theory (DFT) approach (B3LYP/6-311+G**) and experimental (potentiometric and spectrophotometric) analysis for a thorough understanding of the structure...
-
Interactions of positrons with atoms and molecules
PublicationThe positron is the antiparticle of the electron. It has the same mass as the electron, but opposite charge. The understanding of the interactions of positrons with normal matter, like atoms and molecules, is of interest in various scientific fields, like nuclear medicine, plasma physics and astronomy. In this talk we will give a short introduction to some theoretical methods to describe the interactions of positrons with atoms...
-
Frontiers in Molecular Biosciences
Journals -
MOLECULAR AND CELLULAR BIOCHEMISTRY
Journals -
MOLECULAR AND CELLULAR PROBES
Journals -
Density functional theory-based simulations of sum frequency generation spectra involving methyl stretching vibrations: effect of the molecular model on the deduced molecular orientation and comparison with an analytical approach
PublicationThe knowledge of the first hyperpolarizability tensor elements of molecular groups is crucial for a quantitative interpretation of the sum frequency generation (SFG) activity of thin organic films at interfaces. Here, the SFG response of the terminal methyl group of a dodecanethiol (DDT) monolayer has been interpreted on the basis of calculations performed at the density functional theory (DFT) level of approximation. In particular,...
-
Beata Krawczyk dr hab.
PeopleBeata Krawczyk, PhD, Professor Academic degrees, education, qualifications: B. Krawczyk earned his master degree in Biology at the University of Gdansk, Biology Faculty, in 1986, and her PhD in Molecular Biology at the University of Gdansk, Biology Faculty, in 1996. Postdoctoral degree (habilitation) in biological sciences in the discipline biology, Faculty of Natural Sciences, University of Szczecin, Szczecin, in 2009. In 2012...
-
CELLULAR & MOLECULAR BIOLOGY LETTERS
Journals -
CURRENT ISSUES IN MOLECULAR BIOLOGY
Journals -
CURRENT OPINION IN MOLECULAR THERAPEUTICS
Journals -
Contrast Media & Molecular Imaging
Journals -
Biochemistry and Molecular Biology Education
Journals -
CELLULAR AND MOLECULAR LIFE SCIENCES
Journals -
JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY
Journals -
EXPERT REVIEWS IN MOLECULAR MEDICINE
Journals -
Journal of Atomic and Molecular Sciences
Journals -
Gene Therapy and Molecular Biology
Journals -
Cellular and Molecular Gastroenterology and Hepatology
Journals -
Journal of Molecular and Engineering Materials
Journals -
Molecular Therapy-Nucleic Acids
Journals -
Genetic Testing and Molecular Biomarkers
Journals -
PEDIATRIC PATHOLOGY & MOLECULAR MEDICINE
Journals -
PHYSIOLOGY AND MOLECULAR BIOLOGY OF PLANTS
Journals -
EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
Journals -
Advances in Cellular and Molecular Otolaryngology
Journals -
NATURE STRUCTURAL & MOLECULAR BIOLOGY
Journals -
International Journal of Molecular Biology
Journals -
APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY
Journals -
Progress in molecular and subcellular biology
Journals -
Molecular Imaging and Radionuclide Therapy
Journals -
Molecular Systems Design & Engineering
Journals -
Current Protocols in Molecular Biology
Journals -
Molecular Genetics and Metabolism Reports
Journals -
Molecular Biology Research Communications
Journals -
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
Journals -
Reports of Biochemistry and Molecular Biology
Journals -
International Journal of Molecular Imaging
Journals -
Nuclear Medicine and Molecular Imaging
Journals -
Molecular Genetics & Genomic Medicine
Journals -
Journal of Molecular Biology Research
Journals -
JOURNAL OF MOLECULAR MEDICINE-JMM
Journals -
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
Journals -
Food Chemistry: Molecular Sciences
Journals -
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
Journals -
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
Journals -
Journal of Micromechanics and Molecular Physics
Journals -
BMC Molecular and Cell Biology
Journals