Filters
total: 22984
-
Catalog
- Publications 2066 available results
- Journals 247 available results
- Publishing Houses 1 available results
- People 159 available results
- Inventions 9 available results
- Projects 32 available results
- Research Teams 1 available results
- e-Learning Courses 77 available results
- Events 31 available results
- Open Research Data 20361 available results
displaying 1000 best results Help
Search results for: prostate cancer
-
Human UDP-Glucuronosyltransferases: Effects of altered expression in breast and pancreatic cancer cell lines.
PublicationIncreased aerobic glycolysis and de novo lipid biosynthesis are common characteristics of invasive cancers. UDP-glucuronosyltransferases (UGTs) are phase II drug metabolizing enzymes that in normal cells possess the ability to glucuronidate these lipids and speed their excretion; however, de-regulation of these enzymes in cancer cells can lead to an accumulation of bioactive lipids, which further fuels cancer progression. We hypothesize...
-
Adipokine and cytokine levels in patients with adrenocortical cancer, subclinical Cushing's syndrome and healthy controls
PublicationIntroduction In recent years researchers have focused at hormonal activity in Cushing’s syndrome (CS) in connection with metabolic disorders and the role of adipokines and cytokines secreted by the adipose tissue. The aim of the study was to investigate levels of adipokines and cytokines in patients with: subclinical CS (SCS) – in relation to hormonal parameters of hypercortisolemia, and, adrenocortical cancer (ACC). Materials...
-
Methylene Blue Near-Infrared Fluorescence Imaging in Breast Cancer Sentinel Node Biopsy
PublicationIntroduction: Fluorescence-based navigation for breast cancer sentinel node biopsy is a novel method that uses indocyanine green as a fluorophore. However, methylene blue (MB) also has some fluorescent properties. This study is the first in a clinical series presenting the possible use of MB as a fluorescent dye for the identification of sentinel nodes in breast sentinel node biopsy. Material and methods: Forty-nine patients with...
-
Tetrahydroquinolinone derivatives exert antiproliferative effect on lung cancer cells through apoptosis induction
PublicationThe anticancer properties of quinolones is a topic of interest among researchers in the scientific world. Because these compounds do not cause side effects, unlike the commonly used cytostatics, they are considered a promising source of new anticancer drugs. In this work, we designed a brief synthetic pathway and obtained a series of novel 8-phenyltetrahydroquinolinone derivatives functionalized with benzyl-type moieties at position...
-
A Range of Cancers Is Associated with the rs6983267 Marker on Chromosome 8
Publication -
Design, synthesis and high antitumor potential of new unsymmetrical bisacridine derivatives towards human solid tumors, specifically pancreatic cancers and their unique ability to stabilize DNA G-quadruplexes
PublicationNew promising unsymmetrical bisacridine derivatives (UAs), have been developed. Three groupsincluding 36 compounds were synthesized by the condensation of 4-nitro or 4-methylacridinone, imi-dazoacridinone and triazoloacridinone derivatives with 1-nitroacridine compounds linked with anaminoalkyl chain. Cytotoxicity screening revealed the high potency of these compounds against severaltumor cell lines. Particularly, imidazoacridinone-1-nitroacridine...
-
Facile synthetic route to selectively protected spermidine homologues
PublicationW wyniku opracowanej procedury otrzymano kilka selektywnie chronionych homologów spermidyny. Reakcja cyjanoetylowania monochronionych diamin pozwoliła na otrzymanie nitryli, które przekształcano w amidy pierwszorzędowe. Degradacja Hofmanna amidów doprowadziła do otrzymania finalnych związków.
-
EEDI Impact for a Tanker
PublicationReferat przedstawia sposób analizy wskaźnika EEDI zgodnie z wymaganiami IMO-MEPC w zależności od parametrów głównych, prędkości, charakterystyk oporowych oraz układu napędu statku dla wybranego tankowca typu Aframax. W analizie uwzględniono, także układ wytwarzania mocy elektrycznej wraz z innymi układami pomocniczymi tankowca, które są odbiornikami wytwarzanej mocy.
-
Asian Pacific Journal of Cancer Prevention
Journals -
Blood and Lymphatic Cancer-Targets and Therapy
Journals -
Breast Cancer-Basic and Clinical Research
Journals -
Journal of the Egyptian National Cancer Institute
Journals -
Journal of Cancer Survivorship-Research and Practice
Journals -
Journal of the National Comprehensive Cancer Network
Journals -
Chinese Journal of Cancer Prevention and Treatment
Journals -
Japanese Journal of Head and Neck Cancer
Journals -
International Journal of Cancer Research and Prevention
Journals -
Journal of the National Cancer Institute. Monographs
Journals -
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
Journals -
Journal of Obstetrics, Gynecology and Cancer Research
Journals -
Current Problems in Cancer: Case Reports
Journals -
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
Journals -
Anti-Cancer Agents in Medicinal Chemistry
Journals -
Antitumor 1-nitroacridine derivative C-1748 induces significant apoptosis in pancreatic cancer cells.
PublicationPancreatic cancer is the fifth leading cause of cancer death and has the lowest survival rate of any solid cancer in the industrial countries. The poor prognosis of pancreatic cancer results from its tendency for late presentation, aggressive invasion, early metastasis, and resistance to chemotherapy. Gemcitabine still remains the best chemotherapeutic agent available for the treatment of advanced pancreatic cancer. However, gemcitabine...
-
Cardioprotection during cancer chemotherapy with the use of natural antioxidants: review of literature and results of own studies
PublicationDoniesienie poświęcone jest wykorzystaniu naturalnych antyoksydantów w ochronie mięśnia sercowego przed toksycznym działaniem antracyklin wykorzystywanych w leczeniu nowotworów. Pokazane zostało działanie ochronne kilku związków oraz zwierających je składników żywności w tym buraka czerwonego, który był przedmiotem badań własnych.
-
Imidazoacridinone C-1311 induces both autophagy and senescence in human lung cancer A549 cells
PublicationNiedrobnokomórkowy rak płuc (ang. NSCLC, non-small cell lung cancer), stanowiący blisko 80-87% wszystkich przypadków, jest najczęściej występującą formą raka płuc. Skuteczność dotychczas stosowanych chemoterapeutyków w stosunku do tej formy raka jest bardzo ograniczona dlatego poszukuje się nowych związków o lepszych właściwościach leczniczych. Imidazoakrydon C-1311 wykazuje wysoką aktywność cytotoksyczną wobec komórek niedrobnokomórkowego...
-
Extracellular Matrix Proteins Expression Profiling in Chemoresistant Variants of the A2780 Ovarian Cancer Cell Line
Publication -
Positive electrostatic therapy of metastatic tumors: selective induction of apoptosis in cancer cells by pure charges
Publication -
Comparison of RP-HPLC columns used for determination of nucleoside metabolic patterns in urine of cancer patients
Publication -
A novel green one-step synthesis of gold nanoparticles using crocin and their anti-cancer activities
Publication -
Telomere Length and Risk of Major Adverse Cardiac Events and Cancer in Obstructive Sleep Apnea Patients
Publication -
Combinatory Treatment with miR-7-5p and Drug-Loaded Cubosomes Effectively Impairs Cancer Cells
Publication -
Global wealth disparities drive adherence to COVID-safe pathways in head and neck cancer surgery
Publication -
Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study
Publication -
Selective inhibition of cancer cells' proliferation by compounds included in extracts from Baltic Sea cyanobacteria
Publication -
Discrimination of normal oral mucosa from oral cancer by mass spectrometry imaging of proteins and lipids
Publication -
EP-1817: Radiotherapy-related changes in serum proteome patterns of head and neck cancer patients
Publication -
p53 Gene status in relation to ex vivo chemosensitivity of non-small cell lung cancer
Publication -
Polymer-free cubosomes for simultaneous bioimaging and photodynamic action of photosensitizers in melanoma skin cancer cells
Publication -
Biological effects in photodynamic treatment combined with electropermeabilization in wild and drug resistant breast cancer cells
Publication -
Altered Expression of ESR1, ESR2, PELP1 and c-SRC Genes Is Associated with Ovarian Cancer Manifestation
Publication -
Serum levels of IL-6, IL-8 and CRP as prognostic factors in epithelial ovarian cancer
Publication -
Molecular mechanism(s) of regulation(s) of c-MET/HGF signaling in head and neck cancer
Publication -
Poly(amidoamine) Dendrimer/Camptothecin Complex: From Synthesis to In Vitro Cancer Cell Line Studies
Publication -
Molecular modeling and evaluation of novel dibenzopyrrole derivatives as telomerase inhibitors and potential drug for cancer therapy
PublicationDuring previous years, many studies on synthesis, as well as on anti-tumor, anti-inflammatory and anti-bacterial activities of the pyrazole derivatives have been described. Certain pyrazole derivatives exhibit important pharmacological activities and have proved to be useful template in drug research. Considering importance of pyrazole template, in current work the series of novel inhibitors were designed by replacing central...
-
Urinary 5-hydroxymethyluracil and 8-oxo-7,8-dihydroguanine as potential biomarkers in patients with colorectal cancer
Publication -
8-Oxo-7,8-dihydroguanine and uric acid as efficient predictors of survival in colon cancer patients
Publication -
A different methylation profile of circadian genes promoter in breast cancer patients according to clinicopathological features
Publication -
Evidence for attenuated cellular 8-oxo-7,8-dihydro-2′-deoxyguanosine removal in cancer patients
Publication -
Serum Metabolite Profiles in Participants of Lung Cancer Screening Study; Comparison of Two Independent Cohorts
Publication