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Search results for: CYCLOSPORINE
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Label‐free optical detection of cyclosporine in biological fluids
PublicationIn this paper, a spectroscopic method for determination of cyclosporine concentrations in biological fluids is presented. Blood plasma and hemoglobin solutions are chosen for the experiment. For various cyclosporine concentrations in blood plasma and hemoglobin, absorbance measurements in spectra range from 600 to 1100 nm are performed. The measurement results are analyzed by the use of a dedicated algorithm. The obtained data...
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Cyclosporine CsA—The Physicochemical Characterization of Liposomal and Colloidal Systems
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Development and validation of UHPLC method for the determination of cyclosporine A in biological samples
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Wettability and Stability of Naproxen, Ibuprofen and/or Cyclosporine A/Silica Delivery Systems
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Temperature-dependent interactions in the chitosan/cyclosporine A system at liquid–air interface
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CHARACTERIZATION OF MIXED LANGMUIR MONOLAYERS OF CYCLOSPORINE A WITH THE PHOSPHOLIPID DPPC AT THE CHITOSAN SUBPHASE
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Properties of the Langmuir and Langmuir–Blodgett monolayers of cholesterol-cyclosporine A on water and polymer support
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Effect of chitosan on the interactions between phospholipid DOPC, cyclosporine A and lauryl gallate in the Langmuir monolayers
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Ocular irritation and cyclosporine A distribution in the eye tissues after administration of Solid Lipid Microparticles in the rabbit model
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Optical-Spectrometry-Based Method for Immunosuppressant Medicine Level Detection in Aqueous Solutions
PublicationIn this paper, an investigation into detecting immunosuppressive medicine in aqueous solutions using a spectrometry-based technique is described. Using optical transmissive spectrometry, absorbance measurements in the spectra range from 250 nm to 1000 nm were carried out for different cyclosporine A (CsA) concentrations in aqueous solutions. The experiment was conducted for samples both with and without interferent substances—glucose...
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Dominant Pathways of Adenosyl Radical-Induced DNA Damage Revealed by QM/MM Metadynamics
PublicationBrominated nucleobases sensitize double stranded DNA to hydrated electrons, one of the dominant genotoxic species produced in hypoxic cancer cells during radiotherapy. Such radiosensitizers can therefore be administered locally to enhance treatment efficiency within the solid tumor while protecting the neighboring tissue. When a solvated electron attaches to 8-bromoadenosine, a potential sensitizer, the dissociation of bromide...