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Optical-Spectrometry-Based Method for Immunosuppressant Medicine Level Detection in Aqueous Solutions
Abstract
In this paper, an investigation into detecting immunosuppressive medicine in aqueous solutions using a spectrometry-based technique is described. Using optical transmissive spectrometry, absorbance measurements in the spectra range from 250 nm to 1000 nm were carried out for different cyclosporine A (CsA) concentrations in aqueous solutions. The experiment was conducted for samples both with and without interferent substances—glucose and sodium chloride. Using a dedicated algorithm, the measured data was analyzed and a high correlation coefficient R2 = 0.8647 was achieved. The experiment showed that the described technique allowed for the detection of various CsA concentration levels in a selective, label-free and simple way. This method could be used in medicine, veterinary medicine and laboratory diagnostics.
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Authors (6)
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Barbara Bułło-Piontecka
- Gdański Uniwersytet Medyczny, Wydział Lekarski Katedra Nefrologii, Transplantologii i Chorób Wewnętrznych
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Michał Wąsowicz dr.
- Szkoła Główna Gospodarstwa Wiejskiego, Wydział Medycyny Weterynaryjnej Katedra Nauk Morfologicznych
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Details
- Category:
- Articles
- Type:
- artykuł w czasopiśmie wyróżnionym w JCR
- Published in:
-
SENSORS
no. 18,
edition 7,
pages 1 - 9,
ISSN: 1424-8220 - Language:
- English
- Publication year:
- 2018
- Bibliographic description:
- Marzejon M., Kosowska M., Majchrowicz D., Bułło-Piontecka B., Wąsowicz M., Jędrzejewska-Szczerska M.: Optical-Spectrometry-Based Method for Immunosuppressant Medicine Level Detection in Aqueous Solutions// SENSORS. -Vol. 18, iss. 7 (2018), s.1-9
- DOI:
- Digital Object Identifier (open in new tab) 10.3390/s18072001
- Verified by:
- Gdańsk University of Technology
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