Jarosław Józef Spychała

Publikacje naukowe

Dokumenty konferencyjne

Wartościowe komunikaty

Patenty USA (w stylu ACS)

19 indywidualnych artykułów

10 wieloautorskich publikacji (studia podoktoranckie)

11 unikalnych patentów (studia podoktoranckie)

Dykstra, C. C.; Tidwell, R. R.; Boykin, D. W.; Wilson, W. D.; Spychala, J.; Das, B. P.; Kumar, A. Fluorescence Detection Method for Nucleic Acids and Cytoskeletal Cmponents Using bis-Dication Arylfurans. Japanese Patent JP3098545B2, October 16, 2000. https://patents.google.com/patent/JP3098545B2/en

Boykin, D. W.; Das, B. P.; Dykstra, C. C.; Kumar, A.; Spychala, J.; Tidwell, R. R.; Wilson, W. D. Method of Fluorescent Detection of Nucleic Acids and Cytoskeleton Elements Using bis-Dicationic Aryl Furans, and Kits Useful Therefore. Australian Patent AU699223B2, November 26, 1998. https://patents.google.com/patent/AU699223B2/en

Dykstra, C. C.; Tidwell, R. R.; Boykin, D. W.; Wilson, W. D.; Spychala, J.; Das, B. P.; Kumar, A. Fluorescent Detection of Nucleic Acids Using Bisdicationic Aryl Furan Derivatives. New Zealand Patent NZ285309A, October 28, 1998. https://patents.google.com/patent/NZ285309A/en

Dykstra, C. C.; Tidwell, R. R.; Boykin, D. W.; Wilson, W. D.; Spychala, J.; Das, B. P.; Kumar, A. Method of Fluorescent Detection of Nucleic Acids and Cytoskeleton Elements Using bis-Dicationic Aryl Furans, and Kits Useful Therefore. US Patent 5,723,288, March 3, 1998. https://patents.google.com/patent/US5723288A/en https://patentimages.storage.googleapis.com/d7/ff/48/f64b182b94c23a/US5723288.pdf

Dykstra, C. C.; Tidwell, R. R.; Boykin, D. W.; Wilson, W. D.; Spychala, J.; Das, B. P.; Kumar, A. Method of Fluorescent Detection of Nucleic Acids and Cytoskeleton Elements Using bis-Dicationic Aryl Furans. US Patent 5,594,138, January 14, 1997. https://patentimages.storage.googleapis.com/72/f2/3d/fde0963ccc24ed/US5594138.pdf https://patents.google.com/patent/US5594138A/en

Dykstra, C. C.; Tidwell, R. R.; Boykin, D. W.; Wilson, W. D.; Spychala, J.; Das, B. P.; Kumar, A. Method of Fluorescent Detection of Nucleic Acids and Cytoskeleton Elements Using bis-Dicationic Aryl Furans. European Patent Office EP0758453A1, February 19, 1997. https://patents.google.com/patent/EP0758453A1/en

Dykstra, C. C.; Tidwell, R. R.; Boykin, D. W.; Spychala, J.; Das, B. P.; Kumar, A. Fluorescence Detection Process of Nucleic Acids and Cytoskeletal Elements Using bis-Dicationic Aryl Furans (Processo de detecção por fluorescência de ácidos nucléicos e de elementos citoesqueléticos usando aril furanos bis-dicatiônicos). Brazil Patent BR9507616A, August 19, 1997. https://patents.google.com/patent/BR9507616A/en

Dykstra, C. C.; Tidwell, R. R.; Boykin, D. W.; Wilson, W. D.; Spychala, J.; Das, B. P.; Kumar, A. Method of Fluorescent Detection of Nucleic Acids and Cytoskeleton Elements Using bis-Dicationic Aryl Furans. Chinese Patent CN1151209A, June 4, 1997. https://patents.google.com/patent/CN1151209A/en

Boykin, D. W.; Das, B. P.; Dykstra, C. C.; Kumar, A.; Spychala, J.; Tidwell, R. R.; Wilson, W. D. Method of Fluorescent Detection of Nucleic Acids and Cytoskeleton Elements Using bis-Dicationic Aryl Furans. Hungarian Patent HUT76440A, August 28, 1997. https://patents.google.com/patent/HUT76440A/en

Dykstra, C. C.; Tidwell, R. R.; Boykin, D. W.; Wilson, W. D.; Spychala, J.; Das, B. P.; Kumar, A. Method of Fluorescent Detection of Nucleic Acids and Cytoskeleton Elements Using bis-Dicationic Aryl Furans. PCT Int. Appl. WO 95 30, 901, November 16, 1995. C.A. 124: 140390f. http://v3.espacenet.com/textdoc?DB=EPODOC&IDX=WO9530901&F=0

Dykstra, C. C.; Tidwell, R. R.; Boykin, D. W.; Das, B. P.; Kumar, A.; Spychala, J.; Wilson, W. D. Method of Fluorescent Detection of Nucleic Acids and Cytoskeleton Elements Using bis-Dicationic Aryl Furans. Canadian Patent CA2189125A1, November 16, 1995. https://patents.google.com/patent/CA2189125A1/en

13 artykułów wieloautorskich (badania podoktorskie)

Dutkiewicz, G.; Borowiak, T.; Spychala, J. 4,4'-(1,2,4,5-Tetrazine-3,6-diyl)dibenzonitrile. Acta Cryst. 2009, E65, o824. https://doi.org/10.1107/s1600536809008599

Dutkiewicz, G.; Borowiak, T.; Spychala, J. (Z)-N-[2-(Dimethylammonio)ethyl]thioacetamide Chloride. Acta Cryst. 2008, E64, o229. https://doi.org/10.1107/s1600536807064872

Borowiak, T.; Dutkiewicz, G.; Spychala, J. Supramolecular Motifs in 1-(2-Cyanoethyl)thymine and 1-(3-Cyanopropyl)thymine. Acta Cryst. 2007, C63, o201-o203. https://doi.org/10.1107/s0108270107006385

Borowiak, T.; Dutkiewicz, G.; Spychala, J. Molecular Packing in (5-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)acetamide. Acta Cryst. 2006, C62, o344-o345. https://doi.org/10.1107/s0108270106015460

Latosinska, J. N.; Seliger, J.; Grechishkin, V. S.; Spychala, J. Studies of the Electronic Structure of 4-N-Cytosine Derivatives by NMR-NQR Double Resonance Spectroscopy. Magn. Reson. Chem. 1999, 37, 881-884. https://doi.org/10.1002/(sici)1097-458x(199912)37:12<881::aid-mrc582>3.0.co;2-h

Nogaj, B.; Glaser, A.; Spychala, J. NQR Studies of the Electronic Structure of Arylcytosines and Arylisocytosines. Magn. Reson. Chem. 1996, 34, 995-997. https://doi.org/10.1002/(sici)1097-458x(199612)34:12<995::aid-omr1>3.0.co;2-0

Spychala, J.; Plaziak, A. S.; Boykin. D. W. Mass Spectrometry of Diaryl-1,3,5-triazines. Polish Chemical Society Meeting, Poznan, Poland, Sept 23-26, 1996; S-5, D-62. https://www.slideshare.net/JaroslawSpychala/mass-spectrometry-of-diaryl135triazines-research-poster-s5-d62

Nogaj, B.; Glaser, A.; Spychala, J. Study on Electronic Structure of Selected Arylcytosines and Arylisocytosines by Means of NQR Spectroscopy. XXVII All-Polish Seminar on the Nuclear Magnetic Resonance and Its Application 1995, 143-146 (1995-12-31 | Conference paper). https://www.osti.gov/etdeweb/servlets/purl/604532

Glaser, A.; Kasprzak, J.; Nogaj, B.; Spychala, J. Electronic Structure of Selected Aryl Cytosines and Aryl Isocytosines Investigated by Means of ³⁵Cl-NQR Spectroscopy. XXVI All-Polish Seminar on the Nuclear Magnetic Resonance and Its Application 1994, 202-207 (1994-12-31 | Conference paper). https://www.osti.gov/etdeweb/biblio/603250

Plaziak, A. S.; Spychala, J.; Golankiewicz, K. An Evaluation of the Ortho Effect in iso-Cytosine Derivatives: 2-Aralkylamino- and 2-Arylamino-3,4-dihydropyrimidin-4(3H)-ones. Polish J. Chem. 1993, 67, 849-856. https://doi.org/10.1002/chin.199338045

Brzezinski, B.; Spychala, J.; Golankiewicz, K.; Zundel, G. Intramolecular Li⁺ and Na⁺ Bonds in N-(1,6-Dihydro-6-oxypyrimidin-2-yl)Amino Acids: Cation Polarizabilities Studied by Fourier-transform Infrared Spectroscopy. J. Chem. Soc. Faraday Trans. 1992, 88, 1391-1393. https://doi.org/10.1039/ft9928801391

Plaziak, A.; Spychala, J.; Wojtowicz, H.; Langer, J.; Thiel-Pawlicka, H.; Golankiewicz, K. Ortho Effect in the Mass Spectrometric Behaviour of N-(Pyrimidinyl-4-yl)aminobenzoic Acids and their Methyl Esters. Org. Mass Spectrom. 1992, 27, 1293-1298. https://doi.org/10.1002/oms.1210271124

Hladon, B.; Sloderbach, A.; Radosh, P.; Spychala, J.; Golankiewicz, K. In vitro Cytostatic Activity of Some Amino Acid 4-N-Substituted Cytosines. Arch. Immunol. Ther. Exp. 1992, 40, 145-150. https://pubmed.ncbi.nlm.nih.gov/1299173

15 publikacji i rozpraw (doktorat i praca magisterska)

Spychala, J. Synthesis, Structure, and Photochemistry of N⁴-Substituted Cytosines. Ph.D. Dissertation, Adam Mickiewicz University, Poznan, Poland, 1991. https://nauka-polska.pl/#/profile/scientist?id=11915&_k=igp82v

Plaziak, A. S.; Spychala, J.; Golankiewicz, K. Mass Spectrometry of N-(Pyrimidinyl-2- yl)amino Acids and Their Methyl Esters. Org. Mass Spectrom. 1991, 26, 1092-1094. https://doi.org/10.1002/oms.1210261212

Spychala, J.; Golankiewicz, K. Selective Deuteration of 4-N-Methylcytosines. Biochem. Biophys. Res. Commun. 1990, 169, 517-23. https://doi.org/10.1016/0006-291X(90)90361-P

Plaziak, A. S.; Celewicz, L.; Spychala, J.; Golankiewicz, K. Mass Spectrometry of Some Methyl Esters of N-4-Pyrimidinylamino Acids: Rearrangements of the Ions Occurring on Electron-impact Ionization. Org. Mass Spectrom. 1990, 25, 93-96. https://doi.org/10.1002/oms.1210250202

Spychala, J.; Golankiewicz, K. The Efficient Method of Synthesis of 4-N-Arylcytosines. Synth. Commun. 1990, 20, 1899-1904. https://doi.org/10.1080/00397919008053119

Plaziak, A. S.; Celewicz, L.; Spychala, J.; Golankiewicz, K. Mass Spectrometry of 4N-Pyrimidinyl Amino Acids. Org. Mass Spectrom. 1989, 24, 55-58. https://doi.org/10.1002/oms.1210240111

Plaziak, A. S.; Spychala, J.; Golankiewicz, K. Stabilization of Even-electron Ions in 4-Aminosubstituted Cytosines. Appearance of the Strong Ortho Effect Between an Aryl Substituent and the Pyrimidinyl Ring. Org. Mass Spectrom. 1989, 24, 1045-1050. https://doi.org/10.1002/oms.1210241203

Spychala, J.; Golankiewicz K. Correlation between the Electron-impact Fragmentation of N⁴-Substituted Cytosines and Their Photoreactivity. Polish Chemical Society Meeting, Gliwice, Poland, Sept 6-9, 1989; 3/P-21. https://orcid.org/0000-0002-9965-2425

Kielczewski, M.; Celewicz, L.; Spychala, J.; Golankiewicz, K. Chiroptical Investigations of Amino Acid Derivatives. Polish Chemical Society Meeting, Lodz, Poland, Sept 14-17, 1988; B-15. https://orcid.org/0000-0002-9965-2425

Brzezinski, B.; Celewicz, L.; Spychala, J.; Golankiewicz, K. Intramolecular OH^...N«O^-...H⁺N Hydrogen Bonds in N-(1H-2-Oxo-4-pyrimidinyl)Amino Acids. Chem. Phys. Lett. 1988, 149, 348-354. https://doi.org/10.1016/0009-2614(88)85106-6

Joachimiak, A.; Szymanski, M.; Celewicz, L.; Spychala, J. In Protonation of the L-Tryptophan Amino Group Is Unrequired for TRP Aporepressor Activation - B-28, IV Environmental Scientific Conference of Chemists - Developments and Expectations of Economic Practice, Poznan (Puszcza Zielonka), Poland, Oct 25-26, 1988; Wydawnictwo Naukowe UAM, Poznan, 1988 (Conference paper). https://orcid.org/0000-0002-9965-2425

Plaziak, A. S.; Celewicz, L.; Spychala, J.; Golankiewicz, K. Stabilization of Even electron Ions by Cyclization of Substituents on 3N- and 4N-Nitrogens in 4N-Substituted Cytosines. Org. Mass Spectrom. 1988, 23, 654-658. https://doi.org/10.1002/oms.1210230905

Celewicz, L.; Spychala, J.; Golankiewicz, K. Photochemical Synthesis of Deuterium Labelled 4-N-Substituted Cytosines. J. Labelled Compd. Radiopharm. 1988, 25, 1401-1405. https://doi.org/10.1002/jlcr.2580251214

Celewicz, L.; Spychala, J.; Golankiewicz, K. Photochemical Synthesis of N⁴-Substituted Cytosines. Synth. Commun. 1987, 17, 1939-1950. https://doi.org/10.1002/chin.198831183

Spychala, J. Synthesis of Sulfur and Selenium Containing Uridine and Cytidine Analogues. Master’s Dissertation, Adam Mickiewicz University, Poznan, Poland, 1984. https://www.ncbi.nlm.nih.gov/myncbi/1FKxffUKGgugLE/bibliography/public/

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Światowa Encyklopedia Biograficzna - Księga Uczynków i Księga Życia

Zwolennicy naukowca (followers): Shahrazad Ali (pisarka), Chris Bridges (aktor, muzyk, raper), Paul Douglas Coverdell (senator), Sandra Deer (autor, dramatopisarz), Steven Douglas Hales (wychowawca, autor), Joe Frank Harris (na zdjęciu: gubernator, polityk, ustawodawca), Eliana Hirano (wychowawca), Ellen Johnson (lingwistka, wychowawca), Frances Johnston (doradca w dziedzinie badań lekarskich), Konstanty Kalinowski (historyk sztuki polskiej), Kenneth D. Lewis (bankier), Osayimwense Osa (pisarz, wychowawca), Stephen Richard Prothero (pisarz, wychowawca), Julia Roberts (sławna aktorka, producentka, gwiazda hollywoodzka: Pretty Woman 1990), Liliana Sikorska (profesor, wychowawca), Karin Slaughter (powieściopisarka, autorka, literatka), Linda Stone (prezenterka, kierownik handlowy), Ajay Subramanian (matematyk, profesor), Richard Alan Wright (wychowawca, autor).

The Historic Boykins Team (Georgia State University, Department of Chemistry, Kell Hall, Atlanta, Georgia, USA): Marek, Agnieszka, Regents Professor David, Jarek, and Arvind as postdoctoral associates. Celem staży podoktoranckich jest umożliwienie wybitnym młodym uczonym odbycie praktyk w najlepszych ośrodkach naukowych świata. Od młodych doktorów oczekuje się publikacji w renomowanych czasopismach naukowych rangi światowej i umocnienia swojej pozycji w krajowym i międzynarodowym obiegu naukowym. Ostatecznym celem stanowiska badawczego było prowadzenie dodatkowych, zaawansowanych badań wykraczających poza stopień doktora, pogłębianie wiedzy z konkretnej dziedziny naukowej w celu uzyskania lepszych umiejętności i nowych metod badawczych do kontynuowania kariery w środowisku akademickim. Badania są uważane za niezbędne w realizacji misji naukowej od doktora do doświadczonego naukowca. Wysokiej klasy prace badawcze ze stażu mają bardzo dobrą reputację i publikacje wyróżniają się wysokimi wskaźnikami bibliometrycznymi.