Opis
This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
The detailed information about the patient, sample, and diagnosis are as follows:
Patient:
Age: 65
Clinical description: Patient with pancytopenia with increasing fatigue. As a result of the cytological smear of the bone marrow, signs of trilinear dysplasia were found
Gender: Male
Diagnosis:Classification: ICD-O_3.2
Classification code: MYELODYSPLASTIC SYNDROMES
Diagnosis: Myelodysplastic syndrome, NOS
Result of the histopathological examination: Myelodysplastic syndrome with multilineage dysplasia (MDS-MDL) Marrow with cellularity of approx. 40% The topography of the main lines of hemopoiesis is slightly disturbed, the M: E ratio is 3: 2. Myeloid line MPO (+/-) / CD15 (+) with preserved segmental maturation (and with features of discrete dysgranulooesis). CD34 (+) / CD117 (+) blasts are diffuse and account for approx. 1% of the marrow cells CD71 (+) erythroid line in the form of poorly delimited islets with different cell composition, including some cells with uneven outline of the nuclei, some cells with megaloid regeneration features e-Cadherin (+) - features of dyserythropoiesis. CD61 (+) megakaryocytes slightly more numerous, with a slight irregularity in distribution. The dominant forms are small and medium ones with hypo- and hyperlobulation of the nucleis, single with micromegakaryocytes morphology. Bone trabeculae without significant pathological changes
Sample:Material: FFPE
Collecting method: Bone marrow biopsy
Topography: HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS
Organ: HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS
Tissue: Bone marrow
Type of staining: positive/HE
Staining: Not applicable
Antibody: Not applicable
Technology:Equipment: Pannoramic 250 3DHistech
Lens: 20x
Organization:Source: Medical University Gdańsk
Plik z danymi badawczymi
hexmd5(md5(part1)+md5(part2)+...)-{parts_count}
gdzie pojedyncza część pliku jest wielkości 512 MBPrzykładowy skrypt do wyliczenia:
https://github.com/antespi/s3md5
Informacje szczegółowe o pliku
- Licencja:
-
otwiera się w nowej karcieCC BY-NC-SAUżycie niekomercyjne - Na tych samych warunkach
- Dane surowe:
- Dane zawarte w datasecie nie zostały w żaden sposób przetworzone.
- Oprogramowanie:
- CaseViewer 2.3
Informacje szczegółowe
- Rok publikacji:
- 2021
- Data zatwierdzenia:
- 2021-10-29
- Data wytworzenia:
- 2021
- Język danych badawczych:
- angielski
- Dyscypliny:
-
- nauki medyczne (Dziedzina nauk medycznych i nauk o zdrowiu)
- DOI:
- Identyfikator DOI 10.34808/c3y6-c970 otwiera się w nowej karcie
- Ethical papers:
- NKBBN/421-306/2020
- Weryfikacja:
- Gdański Uniwersytet Medyczny
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