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• Scar conditions and fibrosis of skin - Male, 50 - Tissue image [6210730043069261]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of SKIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Chloroacridine derivatives as potential anticancer agents which may act as tricarboxylic acid cycle enzyme inhibitors

  Publikacja

  • M. Cichorek
  • A. Ronowska
  • K. Dzierzbicka
  • M. Gensicka-Kowalewska
  • M. Deptuła
  • I. Pelikant-Malecka

  - BIOMEDICINE & PHARMACOTHERAPY - Rok 2020

  The chloroacridines affect biological forms of melanoma in different ways. Amelanotic (Ab) melanoma (with inhibited melanogenesis and higher malignancy) was particularly sensitive to the action of the chloroacridines. The Ab melanoma cells died through apoptosis and through death without caspase activation. Diminished activity of TAC enzymes was noticed among Ab melanoma cells together with ATP/NAD depletion, especially in the...

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