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Wyniki wyszukiwania dla: HYDRAZONYL-THIAZOLES

Wyniki wyszukiwania dla: HYDRAZONYL-THIAZOLES

  • Quinoline-based thiazolyl-hydrazones target cancer cells through autophagy inhibition

    Publikacja
    • V. Ćurčić
    • M. Olszewski
    • N. Maciejewska
    • A. Višnjevac
    • T. Srdić-rajić
    • V. Dobričić
    • A. T. García-sosa
    • S. B. Kokanov
    • J. B. Araškov
    • R. Silvestri... i 4 innych

    - ARCHIV DER PHARMAZIE - Rok 2024

    Heterocyclic pharmacophores such as thiazole and quinoline rings have a significant role in medicinal chemistry. They are considered privileged structures since they constitute several Food and Drug Administration (FDA)-approved drugs for cancer treatment. Herein, we report the synthesis, in silico evaluation of the ADMET profiles, and in vitro investigation of the anticancer activity of a series of novel thiazolyl-hydrazones based...

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