Wyniki wyszukiwania dla: LAPC (YEJM)

• Regulation of the First Committed Step in Lipopolysaccharide Biosynthesis Catalyzed by LpxC Requires the Essential Protein LapC (YejM) and HslVU Protease

  Publikacja

  • D. Biernacka
  • P. Gorzelak
  • G. Klein-Raina
  • S. Raina

  - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - Rok 2020

  We previously showed that lipopolysaccharide (LPS) assembly requires the essential LapB protein to regulate FtsH-mediated proteolysis of LpxC protein that catalyzes the first committed step in the LPS synthesis. To further understand the essential function of LapB and its role in LpxC turnover, multicopy suppressors of ΔlapB revealed that overproduction of HslV protease subunit prevents its lethality by proteolytic degradation...

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