Wyniki wyszukiwania dla: PTD4

• PTD4 Peptide Increases Neural Viability in an In Vitro Model of Acute Ischemic Stroke

  Publikacja

  • J. Mazuryk
  • I. Puchalska
  • K. Koziński
  • M. J. Ślusarz
  • J. Ruczyński
  • P. Rekowski
  • P. Rogujski
  • R. Płatek
  • M. B. Wiśniewska
  • A. Piotrowski... i 7 innych

  - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - Rok 2021

  Ischemic stroke is a disturbance in cerebral blood flow caused by brain tissue ischemia and hypoxia. We optimized a multifactorial in vitro model of acute ischemic stroke using rat primary neural cultures. This model was exploited to investigate the pro-viable activity of cell-penetrating peptides: arginine-rich Tat(49–57)-NH2 (R49KKRRQRRR57-amide) and its less basic analogue, PTD4 (Y47ARAAARQARA57-amide). Our model included glucose...

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