Wyniki wyszukiwania dla: ZWIĄZKI PRZECIWPIERWOTNIAKOWE

• Amphotericin B and Its New Derivatives - Mode of Action

  Publikacja

  • M. Bagiński
  • J. Czub

  - CURRENT DRUG METABOLISM - Rok 2009

  Amphotericin B (AmB) is a well known antifungal and antiprotozoal antibiotic used in the clinic for several decades. Clinicalapplications of AmB, however, are limited by its nephrotoxicity and many other acute side effects which are not acceptable by patientswhen their life is not threaten. In order to improve the therapeutic index of this drug, lipid formulations have been introduced and manyefforts have been made to obtain less...