Exploring the potential of green chemistry in reversed-phase liquid chromatography: A review of sustainable solvents

Oktawia Kalisz; Marek Tobiszewski; Alicja Nowaczyk; Szymon Bocian

doi:10.1016/j.trac.2024.118007

Exploring the potential of green chemistry in reversed-phase liquid chromatography: A review of sustainable solvents

Abstract

This article delves into the growing field of green analytical chemistry, focusing on sustainable solvents for reversed-phase liquid chromatography (RP LC). RP LC is a widely applied technique in the pharmaceutical, food, and environmental analysis industries, consuming vast quantities of toxic and non-renewable solvents that pose serious environmental and health risks. In response to the urgent need for greener alternatives, this review discusses organic solvents such as ethanol, innovative options such as Cyrene and dimethyl carbonate, and surfactants in micellar liquid chromatography (MLC). In addition, the potential of pure water, ionic liquids (ILs), and deep eutectic solvents (DESs) was evaluated. By analyzing the efficacy, environmental impact, and feasibility of green solvents, the review highlights their potential to replace conventional solvents, supporting safer and more sustainable analytical practices. This comprehensive and critical analysis of recent reports aims to guide future research and promote the use of green solvents in RP LC.

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Authors (4)

Oktawia Kalisz
- Uniiwersytet im Mikołaja Kopernika w Toruniu
Marek Tobiszewski dr hab. inż.
Alicja Nowaczyk
- Uniiwersytet im Mikołaja Kopernika w Toruniu
Szymon Bocian
- Uniiwersytet im Mikołaja Kopernika w Toruniu

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Category:

Articles

Type:

artykuły w czasopismach

Published in:

TRAC-TRENDS IN ANALYTICAL CHEMISTRY no. 181,
ISSN: 0165-9936

Language:

English

Publication year:

2024

Bibliographic description:

Kalisz O., Tobiszewski M., Nowaczyk A., Bocian S.: Exploring the potential of green chemistry in reversed-phase liquid chromatography: A review of sustainable solvents// TRAC-TRENDS IN ANALYTICAL CHEMISTRY -Vol. 181, (2024), s.118007-

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