Search
Abstract
Recently, in the field of biomaterials, which are being designed for soft tissue scaffolding, is growing the interest of their modification with natural polymers. Synthetic polymers are often hard, not easy to process and they do not possess fine biodegradable profile. From the other hand natural polymers are biocompatible, but weak when used alone. The combination of natural and synthetic polymers gives the suitable properties for tissue engineering. Polyurethanes in our study represent the synthetic polymers, which are prepared from polyester poly(ethylene-butylene adipate) (EBO), aliphatic 1,6-hexamethylene diisocyanate (HDI) and two different chain extenders 1,4-butanediol (BDO) or 2-[2-(2-hydroxyethoxy)ethoxy]ethanol (TG). In our study we replaced expensive isocyanates like 2,6-diisocyanato methyl caproate (LDI) or 1,4-diisocyanatobutane (BDI) with cost effective HDI. The applied natural polymer was collagen derivative - gelatin. By blending in situ of these two polymers we obtained material with increased biocompatybility and biodegradability suitable for soft tissue engineering.
Citations
-
2 8
CrossRef
-
0
Web of Science
-
3 3
Scopus
Authors (3)
Cite as
Full text
full text is not available in portal
Keywords
Details
- Category:
- Articles
- Type:
- artykuł w czasopiśmie wyróżnionym w JCR
- Published in:
-
TheScientificWorldJOURNAL
no. 2013,
pages 1 - 12,
ISSN: 1537-744X - Language:
- English
- Publication year:
- 2013
- Bibliographic description:
- Kucińska-Lipka J., Gubańska I., Janik H.: Gelatin-Modified Polyurethanes for Soft Tissue Scaffold// TheScientificWorldJOURNAL. -Vol. 2013, nr. ID 450132 (2013), s.1-12
- DOI:
- Digital Object Identifier (open in new tab) 10.1155/2013/450132
- Verified by:
- Gdańsk University of Technology
seen 95 times
Recommended for you
Green Polymer Nanocomposites for Skin Tissue Engineering
- H. Shokrani,
- A. Shokrani,
- M. Jouyandeh
- + 8 authors