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Haemocompatibility Of Non-Functionalized And Plasmachemical Functionalized Detonation Nanodiamond Particles

Abstract

The purpose of this paper is to present the innovative design of microwave plasma system for modification of detonation nanodiamond particles (DNP) using a special rotating drum placed inside the reactor. Nanodiamond particles manufactured by detonation method reveal the biological activity depending on surface functionalization. Plasmachemical modification of detonation nanodiamond particles gives the possibility of controlling surface of nanodiamonds particles in biological tests. In this paper we would like to compare detonation nanodiamond (the grain sizes from 2 to 5 nm) with modified detonation nanodiamond in rotary reactor chamber, by microwave plasma activated chemical vapour deposition (MW PACVD) method in materials research (Raman and FT-IR spectroscopy) and in vitro examinations with full of human blood. The results indicate haemocompatibility of non-modified detonation nanodiamond and modified nanodiamond by MW PACVD method in rotary reactor chamber (modified ND-3) and the presence of haemolysis in commercial detonation nanodiamond.

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DOI:
Digital Object Identifier (open in new tab) 10.1515/amm-2015-0364
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Category:
Articles
Type:
artykuł w czasopiśmie wyróżnionym w JCR
Published in:
ARCHIVES OF METALLURGY AND MATERIALS no. 60, edition 3, pages 2183 - 2189,
ISSN: 1733-3490
Language:
English
Publication year:
2015
Bibliographic description:
Mitura K., Szczerska M., Ceynowa P., Dudek M., Cicha M., Kotela I., Mitura S.: Haemocompatibility Of Non-Functionalized And Plasmachemical Functionalized Detonation Nanodiamond Particles// ARCHIVES OF METALLURGY AND MATERIALS. -Vol. 60, iss. 3 (2015), s.2183-2189
DOI:
Digital Object Identifier (open in new tab) 10.1515/amm-2015-0364
Verified by:
Gdańsk University of Technology

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