Haemocompatibility of Modified Nanodiamonds - Publication - MOST Wiedzy

Search

Haemocompatibility of Modified Nanodiamonds

Abstract

This study reports the interactions of modified nanodiamond particles in vitro with human blood. Modifications performed on the nanodiamond particles include oxygenation with a chemical method and hydrogenation upon chemical vapor deposition (CVD) plasma treatment. Such nanodiamonds were later incubated in whole human blood for different time intervals, ranging from 5 min to 5 h. The morphology of red blood cells was assessed along with spectral measurements and determination of haemolysis. The results showed that no more than 3% of cells were affected by the nanodiamonds. Specific modifications of the nanodiamonds give us the possibility to obtain nanoparticles which are biocompatible with human blood. They can form a basis for the development of nanoscale biomarkers and parts of sensing systems and devices useful in biomedical environments.

Citations

  • 1 1

    CrossRef

  • 0

    Web of Science

  • 1 3

    Scopus

Details

Category:
Magazine publication
Type:
artykuł w czasopiśmie wyróżnionym w JCR
Published in:
Materials no. 10, edition 4, pages 1 - 12,
ISSN: 1996-1944
Language:
English
Publication year:
2017
Bibliographic description:
Wąsowicz M., Ficek M., Wróbel M., Chakraborty R., Fixler D., Wierzba P., Jędrzejewska-Szczerska M.: Haemocompatibility of Modified Nanodiamonds// Materials. -Vol. 10, iss. 4 (2017), s.1-12
DOI:
Digital Object Identifier (open in new tab) 10.3390/ma10040352
Verification:
Gdańsk University of Technology

seen 19 times

Publikacje, które mogą cię zainteresować

Meta Tags