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Abstract
This study reports the interactions of modified nanodiamond particles in vitro with human blood. Modifications performed on the nanodiamond particles include oxygenation with a chemical method and hydrogenation upon chemical vapor deposition (CVD) plasma treatment. Such nanodiamonds were later incubated in whole human blood for different time intervals, ranging from 5 min to 5 h. The morphology of red blood cells was assessed along with spectral measurements and determination of haemolysis. The results showed that no more than 3% of cells were affected by the nanodiamonds. Specific modifications of the nanodiamonds give us the possibility to obtain nanoparticles which are biocompatible with human blood. They can form a basis for the development of nanoscale biomarkers and parts of sensing systems and devices useful in biomedical environments.
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Authors (7)
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Michał Wąsowicz dr.
- SGGW
-
Ruchira Chakraborty
- Bar-Ilan University
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Dror Fixler
- Bar-Ilan University
Cite as
Full text
- Publication version
- Accepted or Published Version
- DOI:
- Digital Object Identifier (open in new tab) 10.3390/ma10040352
- License
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Keywords
Details
- Category:
- Articles
- Type:
- artykuł w czasopiśmie wyróżnionym w JCR
- Published in:
-
Materials
no. 10,
edition 4,
pages 1 - 12,
ISSN: 1996-1944 - Language:
- English
- Publication year:
- 2017
- Bibliographic description:
- Wąsowicz M., Ficek M., Wróbel M., Chakraborty R., Fixler D., Wierzba P., Szczerska M.: Haemocompatibility of Modified Nanodiamonds// Materials. -Vol. 10, iss. 4 (2017), s.1-12
- DOI:
- Digital Object Identifier (open in new tab) 10.3390/ma10040352
- Verified by:
- Gdańsk University of Technology
Referenced datasets
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