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Search results for: CANCER
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Saliva as a first-line diagnostic tool: A spectral challenge for identification of cancer biomarkers
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Application of a three‑dimensional (3D) breast cancer model to study macrophage polarization
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Tissue Rheology as a Possible Complementary Procedure to Advance Histological Diagnosis of Colon Cancer
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Serum MicroRNAs as Xerostomia Biomarkers in Patients With Oropharyngeal Cancer Undergoing Radiation Therapy
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Bayesian multilevel model of micro RNA levels in ovarian-cancer and healthy subjects
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Delving into the Nutraceutical Benefits of Purple Carrot against Metabolic Syndrome and Cancer: A Review
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FGF7 / FGFR2 – JunB signalling counteracts the effect of progesterone in luminal breast cancer
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From chemoresistance to cancer stem cells: the case of BRCP/ABCG2 half transporter
PublicationLudzkie białko ABCG2 jest pompą typu ABC tworzącą homodimery i aktywnie transportującą leki i inne substraty naturalne i syntetyczne. Nadekspresja tego białko prowadzi do oporności na leki przeciwnowotworowe. Białko ABCG2 występuje w wielu formach zmutowanych, różniących się własnościami substratowymi, stąd istotne dla oporności na leki jest jaka forma genu i białka ABCG2 ulega nadekspresji w komórce. Ostatnie badania wskazują,...
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Risk factors assessment and risk prediction models in lung cancer screening candidates
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Vimentin immunoexpression and its prognostic activity in colon cancer among Caucasian patients
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Near-Infrared Fluorescence Image-Guided Surgery in Esophageal and Gastric Cancer Operations
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Can popular films instil carcinophobia? Images of cancer in popular Polish cinema
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Myeloid-derived suppressor cells (MDSCs) in brain cancer: challenges and therapeutic strategies
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The Occurrence of Cancer and of Adenomae in the Large Bowel and the Concentration of N -Nitrosamines in the Gastric Juice
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Advanced Assessment of the Endogenous Hormone Level as a Potential Biomarker of the Urogenital Tract Cancer
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The Relationship of Purpose in Life and Hope in Shaping Happiness Among Patients with Cancer in Poland
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Role of Curcumin and (−)-Epigallocatechin-3-O-Gallate in Bladder Cancer Treatment: A Review
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Altered circadian genes expression in breast cancer tissue according to the clinical characteristics
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The impact of the Polish mass breast cancer screening program on prognosis in the Pomeranian Province
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Prognostic Significance of TOP2A Gene Dosage in HER-2-Negative Breast Cancer
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Therapy with CD4+CD25+ T regulatory cells – should we be afraid of cancer?
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Polymorphisms in nucleotide excision repair genes and susceptibility to colorectal cancer in the Polish population
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Radiation Therapy-Induced Changes in Serum Lipidome of Head and Neck Cancer Patients
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The Role of miRNA in Papillary Thyroid Cancer in the Context of miRNA Let-7 Family
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Altered levels of circulating nuclear and mitochondrial DNA in patients with Papillary Thyroid Cancer
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Prognostic value of 5-microRNA based signature in T2-T3N0 colon cancer
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Synthesis of Usnic Acid Derivatives and Evaluation of Their Antiproliferative Activity against Cancer Cells
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Potential plasma biomarkers of bladder cancer identified by proteomic analysis: A pilot study
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Deep Learning-Based, Multiclass Approach to Cancer Classification on Liquid Biopsy Data
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Impacting the Remedial Potential of Nano Delivery-Based Flavonoids for Breast Cancer Treatment
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Sense of coherence and acceptance of the disease in patients with lung cancer during palliative chemotherapy
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Radiation Therapy–Related Changes in Serum Proteome and Lipidome Are Primarily Associated With a Type of Acute Toxicity: Comparison of Radiation-Induced Effects in Patients Treated Because of Head and Neck Cancer or Prostate Cancer
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Tetrahydroquinolinone derivatives exert antiproliferative effect on lung cancer cells through apoptosis induction
PublicationThe anticancer properties of quinolones is a topic of interest among researchers in the scientific world. Because these compounds do not cause side effects, unlike the commonly used cytostatics, they are considered a promising source of new anticancer drugs. In this work, we designed a brief synthetic pathway and obtained a series of novel 8-phenyltetrahydroquinolinone derivatives functionalized with benzyl-type moieties at position...
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Human UDP-Glucuronosyltransferases: Effects of altered expression in breast and pancreatic cancer cell lines.
PublicationIncreased aerobic glycolysis and de novo lipid biosynthesis are common characteristics of invasive cancers. UDP-glucuronosyltransferases (UGTs) are phase II drug metabolizing enzymes that in normal cells possess the ability to glucuronidate these lipids and speed their excretion; however, de-regulation of these enzymes in cancer cells can lead to an accumulation of bioactive lipids, which further fuels cancer progression. We hypothesize...
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Serum lipid profile discriminates patients with early lung cancer from healthy controls
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Plasma micronutrients, trace elements, and breast cancer in BRCA1 mutation carriers: an exploratory study
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Coordinated reprogramming of renal cancer transcriptome, metabolome and secretome associates with immune tumor infiltration
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Methylene Blue Near-Infrared Fluorescence Imaging in Breast Cancer Sentinel Node Biopsy
PublicationIntroduction: Fluorescence-based navigation for breast cancer sentinel node biopsy is a novel method that uses indocyanine green as a fluorophore. However, methylene blue (MB) also has some fluorescent properties. This study is the first in a clinical series presenting the possible use of MB as a fluorescent dye for the identification of sentinel nodes in breast sentinel node biopsy. Material and methods: Forty-nine patients with...
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The Action Mechanisms, Anti-Cancer and Antibiotic-Modulation Potential of Vaccinium myrtillus L. Extract
PublicationHerbal medicinal products containing Vaccinium myrtillus L. (bilberry) fruits and fruit extracts are widely available in the market. Although bilberry leaves and stems are considered as bio-waste, they contain much higher levels of phenolic compounds than fruits. The study aimed to investigate the antimicrobial and anticancer potential of aerial part extracts from Vaccinium myrtillus L. (V. myrtillus, VM) plants harvested at high...
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MIX2: A Novel Natural Multi-Component Modulator of Multidrug-Resistance and Hallmarks of Cancer Cells
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Coexpression of human chorionic gonadotropin beta subunit and its receptor in nontrophoblastic gynecological cancer
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Decisional DNA for modeling and reuse of experiential clinical assessments in breast cancer diagnosis and treatment
PublicationClinical Decision Support Systems (CDSS) are active knowledge resources that use patient data to generate case specific advice. The fast pace of change of clinical knowledge imposes to CDSS the continuous update of the domain knowledge and decision criteria. Traditional approaches require costly tedious manual maintenance of the CDSS knowledge bases and repositories. Often, such an effort cannot be assumed by medical teams, hence...
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Adipokine and cytokine levels in patients with adrenocortical cancer, subclinical Cushing's syndrome and healthy controls
PublicationIntroduction In recent years researchers have focused at hormonal activity in Cushing’s syndrome (CS) in connection with metabolic disorders and the role of adipokines and cytokines secreted by the adipose tissue. The aim of the study was to investigate levels of adipokines and cytokines in patients with: subclinical CS (SCS) – in relation to hormonal parameters of hypercortisolemia, and, adrenocortical cancer (ACC). Materials...
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The modulatory effect of green tea catechin on drug resistance in human ovarian cancer cells
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Structure–bioavailability relationship study of genistein derivatives with antiproliferative activity on human cancer cell
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Synthesis of New Hydrazone Derivatives and Evaluation of their Efficacy as Proliferation Inhibitors in Human Cancer Cells
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Aberrant repair of etheno–DNA adducts in leukocytes and colon tissue of colon cancer patients
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A potency of plasminogen activation system in long-term prognosis of endometrial cancer: a pilot study
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Drug transporter expression profiling in chemoresistant variants of the A2780 ovarian cancer cell line
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Physical and psychological impairments of women with upper limb lymphedema following breast cancer treatment
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