Search results for: CADMIUM-BREAST CANCER-WARBURG EFFECT-HIF1A-TAMOXIFEN
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Invasive breast carcinoma of no special type - Female, 63 - Tissue image [5230730013289311]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Invasive breast carcinoma of no special type - Female, 63 - Tissue image [5230730013285101]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Invasive breast carcinoma of no special type - Female, 63 - Tissue image [5230730013281631]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Invasive breast carcinoma of no special type - Female, 63 - Tissue image [5230730013286361]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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H2AX phosphorylation, its role in DNA damage response and cancer therapy
PublicationDouble-strand breaks (DSBs) are the most deleterious DNA lesions, which, if left unrepaired, may have severe consequences for cell survival, as they lead to chromosome aberrations, genomic instability, or cell death. Various physical, chemical, and biological factors are involved in DSB induction. Cells respond to DNA damage by activating the so-called DNA damage response (DDR), a complex molecular mechanism developed to detect...
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BREAST, Mammary gland - Female, 55 - Tissue image [5230730013278571]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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BREAST, Mammary gland - Female, 55 - Tissue image [5230730013279361]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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BREAST, Mammary gland - Female, 55 - Tissue image [5230730013276271]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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BREAST, Mammary gland - Female, 55 - Tissue image [5230730013272081]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Invasive breast carcinoma of no special type - Female, 68 - Tissue image [4190730010775471]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Invasive breast carcinoma of no special type - Female, 68 - Tissue image [419073001077821]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Invasive breast carcinoma of no special type - Female, 68 - Tissue image [4190730010773521]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Invasive breast carcinoma of no special type - Female, 68 - Tissue image [4190730010775781]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Evaluation of candidate reference material obtained from selenium - enriched sprouts for the purpose of selenium speciation analysis
PublicationSelenium is an essential element in animals and humans. Diet supplementation with selenium-rich vegetables has better chemoprotective effect than Se (IV) and SeMet. The production of selenium-enriched vegetables requires a preliminary stage in soil preparation, which may subsequently pose a risk of soil contamination. It seems that the sprouting of seeds under controlled conditions would be a good solution for delivering SeMetSeCys...
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Chemical Aspects of Biological Activity of Isothiocyanates and Indoles, the Products of Glucosinolate Decomposition
PublicationThere is growing evidence that cancer chemoprevention employing natural, bioactive compounds may halt or at least slow down the different stages of carcinogenesis. A particularly advantageous effect is attributed to derivatives of sulfur-organic phytochemicals, such as glucosinolates (GLs) synthesized mainly in Brassicaceae plant family. GLs are hydrolysed enzymatically to bioactive isothiocyanates (ITC) and indoles, which exhibit strong...
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Phenolic compounds from Nerium oleander leaves: microwave assisted extraction, characterization, antiproliferative and cytotoxic activities
PublicationA microwave-assisted extraction (MAE) method was used for the extraction of phenolic compounds from Nerium oleander leaves. The influence of variables such as ethanol concentration, microwave power, irradiation time and liquid/solid ratio on polyphenol extraction was modelled using a second-order regression equation based on response surface methodology (RSM). The optimal conditions for MAE were: extraction solvent 35% ethanol...
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018857481]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018856901]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018855201]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018858031]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018852521]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018859321]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018862991]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018851661]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018858791]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018852601]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018851211]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018852411]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018855841]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018857781]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [413073001885421]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018859461]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018852861]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018855341]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [413073001886741]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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The II phase metabolism of endogenous and exogenous compounds, including antitumor chemotherapeutics
PublicationThe II phase metabolism, it is a set of metabolism and excretion pathways of endogenous as well as exogenous compounds including xenobiotics. UDP-glucuronyltransferases (UGTs; EC 2.4.1.17) are the most crucial representatives of II phase enzymes, which are responsible for the transformation of bilirubine and bile acids, steroids and thyroid hormones and lipids. Exogenous compounds, including drugs, carcinogens, environmental pollutants...
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Invasive breast carcinoma of no special type - Female, 65 - Tissue image [7100730013394891]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Invasive breast carcinoma of no special type - Female, 65 - Tissue image [7100730013385801]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Invasive breast carcinoma of no special type - Female, 65 - Tissue image [710073001338881]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Invasive breast carcinoma of no special type - Female, 65 - Tissue image [710073001339411]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Invasive breast carcinoma of no special type - Female, 65 - Tissue image [710073001338921]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Invasive breast carcinoma of no special type - Female, 65 - Tissue image [7100730013391371]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Invasive breast carcinoma of no special type - Female, 65 - Tissue image [7100730013398611]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Invasive breast carcinoma of no special type - Female, 65 - Tissue image [7100730013396731]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Invasive breast carcinoma of no special type - Female, 48 - Tissue image [5280730021738331]
Open Research DataThis is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Invasive breast carcinoma of no special type - Female, 48 - Tissue image [5280730021733921]
Open Research DataThis is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Invasive breast carcinoma of no special type - Female, 48 - Tissue image [5280730021731771]
Open Research DataThis is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Invasive breast carcinoma of no special type - Female, 48 - Tissue image [5280730021733361]
Open Research DataThis is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Modelling charge transfer processes in C2+ -tetrahydrofuran collision for ion-induced radiation damage in DNA building blocks
PublicationInvestigations of collision-induced processes involving carbon ions and molecules of biological interest in particular DNA building blocks, are crucial to model the effect of radiation on cells in order to improve medical treatments for cancer therapy. Using carbon ions appears to be one of the most efficient ways to increase biological effectiveness to damage cancerous cells by irradiating deep-seated tumors. Therefore, interest...
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Anticancer Imidazoacridinone C-1311 is Effective in Androgen-Dependent and Androgen-Independent Prostate Cancer Cells
PublicationAndrogen receptor (AR) plays a crutial role in prostate cancer (PCa) development and metastasis. Here, we reported potent anti-PCa activity of a small molecule imidazoacridinone C-1311. In AR-positive PCa cells, C-1311 was found to inhibit the transcriptional activity of AR uncovering a novel mechanism that may be relevant for its anticancer effect. Mechanistically, C-1311 decreased AR binding to prostate-specific antigen (PSA)...