Search results for: DISCO

• Drug Discovery World

  Journals

  ISSN: 1469-4344

• Blood Cancer Discovery

  Journals

  ISSN: 2643-3230 , eISSN: 2643-3249

• Medicine in Drug Discovery

  Journals

  eISSN: 2590-0986

• Cell Death Discovery

  Journals

  eISSN: 2058-7716

• A Reaction of Thioamides with Zinc Ammoniates Leading to Simple Amidines. Discovery of a New Zwitterionic Monomethylamidine

  Publication

  • J. Spychala

  - CATALYSIS LETTERS - Year 2006

  The reaction of thioamides with the R1R2N-ZnCl ammoniates leads to N-mono-, N,N'-di-, N,N-disubstituted, and unsubstituted amidines with high concns. of amines in abs. ethanol. The efficient direct formation of the N,N'-dimethylamidine can be explained by a greater reactivity of methylamine compared with dimethylamine. Discovery of a new zwitterion (induced by a carbonyl oxygen) suggests that the stabilization in the thymine...

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• A review on computer‐aided chemogenomics and drug repositioning for rational COVID ‐19 drug discovery

  Publication

  • S. Maghsoudi
  • B. Taghavi Shahraki
  • F. Rameh
  • M. Nazarabi
  • Y. Fatahi
  • O. Akhavan
  • M. Rabiee
  • E. Mostafavi
  • E. C. Lima
  • M. Saeb
  • N. Rabiee

  - Chemical Biology & Drug Design - Year 2022

  Application of materials capable of energy harvesting to increase the efficiency and environmental adaptability is sometimes reflected in the ability of discovery of some traces in an environment―either experimentally or computationally―to enlarge practical application window. The emergence of computational methods, particularly computer-aided drug discovery (CADD), provides ample opportunities for the rapid discovery and development...

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• Service and Path Discovery Extensions for Self-forming IEEE 802.11s Wireless Mesh Systems

  Publication

  • K. Gierłowski

  - Year 2012

  With the rapid growth of the quantity and capabilities of end-user electronic devices, both stationary and mobile, they are employed in increasing number of applications. In this situation, wireless network technologies begin to play a crucial role as networks access technologies, as cable-based solutions tend to be of limited utility in case of easily portable or mobile devices. Resulting development of wireless technologies reached...

• International Journal of Legal Discourse

  Journals

  ISSN: 2364-8821 , eISSN: 2364-883X

• Discovering the mechanisms of strain-dependent response of Staphylococcus aureus to photoinactivation: Oxidative stress toleration, endogenous porphyrin level and strain's virulence

  Publication

  • M. Kossakowska
  • J. Nakonieczna
  • A. Kawiak
  • J. Kurlenda
  • K. Bielawski
  • M. Grinholc
  • K. P. Bielawski

  - Photodiagnosis and Photodynamic Therapy - Year 2013

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• Using creative approaches for discovering biomorphic forms for appropriate human habitation in natural environments. Case study of Kashubian Lake District

  Publication

  • A. Kurkowska

  - Cogent Arts & Humanities - Year 2023

  The research process consisted of studies of natural and cultural conditions of the Kashubian Lake District This is an area of exceptional natural conditions. For centuries, it has seen human habitation with respect to landscape values. Given its extensive forest cover and the lack of heterogeneity of natural conditions, the area has become an interesting inspiration for the author’s original project. The project is aimed at searching...

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• Terrae Incognitae-The Journal of the Society for the History of Discoveries

  Journals

  ISSN: 0082-2884 , eISSN: 2040-8706

• Relay-aided Wireless Sensor Network Discovery Algorithm for Dense Industrial IoT utilizing ESPAR Antennas

  Publication

  • F. Ademaj
  • M. Rzymowski
  • H. Bernhard
  • K. Nyka
  • Ł. Kulas

  - IEEE Internet of Things Journal - Year 2021

  Industrial Internet of Things (IIoT) applicationsrequire reliable and efficient wireless communication. Assumingdense Wireless Sensor Networks (WSNs) operating in a harshenvironment, a concept of a Time Division Multiple Access(TDMA) based WSN enriched with Electronically SteerableParasitic Array Radiator (ESPAR) antennas is proposed andexamined in this work. The utilized...

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• Comprehensive Analysis of MILE Gene Expression Data Set Advances Discovery of Leukaemia Type and Subtype Biomarkers

  Publication

  • W. Labaj
  • A. Papiez
  • A. Polanski
  • J. Polanska

  - Interdisciplinary Sciences-Computational Life Sciences - Year 2017

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• Discovery of the anticancer drug vinblastine from the endophytic Alternaria alternata and yield improvement by gamma irradiation mutagenesis

  Publication

  • E. El‐Sayed

  - JOURNAL OF APPLIED MICROBIOLOGY - Year 2021

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• DRUG DISCOVERY TODAY

  Journals

  ISSN: 1359-6446 , eISSN: 1878-5832

• DATA MINING AND KNOWLEDGE DISCOVERY

  Journals

  ISSN: 1384-5810 , eISSN: 1573-756X

• Journal of Biomedical Discovery and Collaboration

  Journals

  ISSN: 1747-5333

• International Journal of Drug Discovery

  Journals

  ISSN: 0975-4423

• Expert Opinion on Drug Discovery

  Journals

  ISSN: 1746-0441 , eISSN: 1746-045X

• Drug Discovery Today: Technologies

  Journals

  ISSN: 1740-6749

• Current Drug Discovery Technologies

  Journals

  ISSN: 1570-1638

• Letters in Drug Design & Discovery

  Journals

  ISSN: 1570-1808 , eISSN: 1875-628X

• Cancer Drug Discovery and Development

  Journals

  ISSN: 2196-9906 , eISSN: 2196-9914

• NATURE REVIEWS DRUG DISCOVERY

  Journals

  ISSN: 1474-1776 , eISSN: 1474-1784

• Data Analysis and Knowledge Discovery

  Journals

  ISSN: 2096-3467

• Webinarium „Drug Discovery, Development & Commercialization”

  Events

  26-11-2020 11:00 - 26-11-2020 14:00

  CTWT PG zaprasza na webinarium „Drug Discovery, Development & Commercialization”. Spotkanie skierowane jest do osób zajmujących się zawodowo lub planujących swoją karierę w dziedzinie opracowywania i rozwoju leków.

• Discours-Revue de Linguistique Psycholinguistique et Informatique

  Journals

  ISSN: 1963-1723

• Wacana Seni-Journal of Art Discourse

  Journals

  ISSN: 1675-3410 , eISSN: 1985-8418

• Latin-American Journal of Discourse Studies

  Journals

  eISSN: 2447-9543

• Dynamic Route Discovery Using Modified Grasshopper Optimization Algorithm in Wireless Ad-Hoc Visible Light Communication Network

  Publication

  • S. Vadivel
  • S. Konda
  • K. R. Balmuri
  • A. Stateczny
  • B. D. Parameshachari

  - Electronics - Year 2021

  In recent times, visible light communication is an emerging technology that supports high speed data communication for wireless communication systems. However, the performance of the visible light communication system is impaired by inter symbol interference, the time dispersive nature of the channel, and nonlinear features of the light emitting diode that significantly reduces the bit error rate performance. To address these problems,...

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• Discovery of phenylselenoether-hydantoin hybrids as ABCB1 efflux pump modulating agents with cytotoxic and antiproliferative actions in resistant T-lymphoma

  Publication

  • W. Ali
  • G. Spengler
  • A. Kincses
  • M. Nové
  • C. Battistelli
  • G. Latacz
  • M. Starek
  • M. Dąbrowska
  • E. Honkisz-Orzechowska
  • A. Romanelli... and 5 others

  - European Journal of Medicinal Chemistry - Year 2020

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• A geophysical, geochemical and microbiological study of a newly discovered pockmark with active gas seepage and submarine groundwater discharge (MET1-BH, central Gulf of Gdańsk, southern Baltic Sea)

  Publication

  • J. Idczak
  • A. Brodecka-Goluch
  • K. Łukawska-Matuszewska
  • B. Graca
  • N. Gorska
  • Z. Klusek
  • P. D. Pezacki
  • J. Bolałek

  - SCIENCE OF THE TOTAL ENVIRONMENT - Year 2020

  High-resolution bathymetric data were collected with a multi-beam echosounder in the southern part of the Baltic Sea (region MET1, Gulf of Gdańsk) revealing the presence of a 10 m deep and 50 m in diameter pockmark (MET1-BH) on the sea bottom (78.7 m). To date, no such structures have been observed to reach this size in the Baltic Sea. The salinity of the near-bottom water in the pockmark was about 2 PSU (about 31.22 mmol/l...

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• A strong preference for the TA/TA dinucleotide step discovered for an acridine-based, potent antitumor dsDNA intercalator, C-1305: NMR-driven structural and sequence-specificity studies

  Publication

  • T. Laskowski
  • W. Andrałojć
  • J. Grynda
  • P. Gwarda
  • J. Mazerski
  • Z. Gdaniec

  - Scientific Reports - Year 2020

  Triazoloacridinone C-1305, a potent antitumor agent recommended for Phase I clinical trials, exhibits high activity towards a wide range of experimental colon carcinomas, in many cases associated with complete tumor regression. C-1305 is a well-established dsDNA intercalator, yet no information on its mode of binding into DNA is available to date. Herein, we present the NMR-driven and MD-refined reconstruction of the 3D structures...

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• Discovery of Novel 3-Hydroxyandrosta-5,7-Diene-17-Carboxylic Acid Derivatives as Anti-Inflammatory Bowel Diseases (IBD) Agents

  Publication

  • J. Chen
  • L. Li
  • J. Liu
  • S. Yuan
  • W. Liao
  • A. Slominski
  • W. Li
  • M. Żmijewski
  • J. Chen

  - European Journal of Medicinal Chemistry - Year 2021

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• IATUL Fall Seminar - Connecting in a disconnected world.

  Events

  15-12-2021 12:00 - 15-12-2021 15:45

    We invite both current community members and other people interested in IATUL's activities to the online seminar on December 15, 2021. During the meeting, we will talk about the mission and activities of the organisation, as well as the benefits of belonging to the IATUL community. In addition, Special Interest Groups (SIGs), analysing...

• Structural Insights into Autoreactive Determinants in Thyroid Peroxidase Composed of Discontinuous and Multiple Key Contact Amino Acid Residues Contributing to Epitopes Recognized by Patients’ Autoantibodies

  Publication

  • M. Dubska
  • J. Banga
  • D. Plochocka
  • G. Hoser
  • E. Kemp
  • B. Sutton
  • A. Gardas
  • M. Gora
  • M. Godlewska

  - ENDOCRINOLOGY - Year 2006

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• Discovery and characterization of RecA protein of thermophilic bacterium Thermus thermophilus MAT72 phage Tt72 that increases specificity of a PCR-based DNA amplification

  Publication

  • A. Stefanska
  • A. Kaczorowska
  • M. Plotka
  • O. Fridjonsson
  • G. Hreggvidsson
  • S. Hjorleifsdottir
  • J. Kristjansson
  • S. Dabrowski
  • T. Kaczorowski

  - JOURNAL OF BIOTECHNOLOGY - Year 2014

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• Integracja międzywarstwowa protokołów RM-AODV Multicast DNS i IPv6 Neighbor Discovery w środowisku sieci standardu IEEE 802.11s

  Publication

  • K. Gierłowski

  - Przegląd Telekomunikacyjny + Wiadomości Telekomunikacyjne - Year 2016

  Wraz z rozwojem bezprzewodowych technik transmisyjnych oraz wzrostem liczby i zasobów urządzeń mobilnych, wzrasta również popularność sieci bezprzewodowe o architekturze mesh, które znajdują rozliczne zastosowania w systemach dostępowych i dystrybucyjnych. W artykule przedstawiono krótką analizę efektywności działania protokołów IPv6 Neighbor Discovery oraz Multicast DNS w środowisku sieci IEEE 802.11s oraz propozycję metody jej...

• CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT

  Journals

  ISSN: 1367-6733

• Journal of Data Mining and Knowledge Discovery

  Journals

  ISSN: 2229-6662

• Recent Patents on CNS Drug Discovery

  Journals

  ISSN: 1574-8898

• Drug Discovery Today: Disease Models

  Journals

  ISSN: 1740-6757

• Current Research in Pharmacology and Drug Discovery

  Journals

  eISSN: 2590-2571

• Medical Hypothesis, Discovery, and Innovation in Ophthalmology

  Journals

  ISSN: 2322-4436 , eISSN: 2322-3219

• An MTA-phosphorylase gene discovered in the metagenomic library derived from Antarctic top soil during screening for lipolytic active clones confers strong pink fluorescence in the presence of rhodamine B.

  Publication

  • H. Cieśliński
  • A. Długołecka
  • J. Kur
  • M. Turkiewicz

  - FEMS MICROBIOLOGY LETTERS - Year 2009

  In this work, we present the construction of a metagenomic library in Escherichiacoli using the pUC19 vector and environmental DNA directly isolated fromAntarctic topsoil and screened for lipolytic enzymes. Unexpectedly, the screeningon agar supplemented with olive oil and rhodamine B revealed one unusual pinkfluorescent clone (PINKuv) out of 85 000 clones. This clone harbored a plasmid,pPINKuv, which has an insert of 8317 bp that...

• ANATOMICAL RECORD PART A-DISCOVERIES IN MOLECULAR CELLULAR AND EVOLUTIONARY BIOLOGY

  Journals

  ISSN: 1552-4884

• Discourse-Journal for Theoretical Studies in Media and Culture

  Journals

  ISSN: 1522-5321 , eISSN: 1536-1810

• Religion and Theology-A Journal of Contemporary Religious Discourse

  Journals

  ISSN: 1023-0807 , eISSN: 1574-3012

• Museums & Social Issues-A Journal of Reflective Discourse

  Journals

  ISSN: 1559-6893 , eISSN: 2051-6193

• Discovery of small-molecule regenerative drugs using a model of complex tissue injury in mice. Transcriptomic responses of neurodevelopmental genes during pharmacologically induced regeneration

  Publication

  • P. Sosnowski

  - Year 2021

  Despite significant development in regenerative medicine, there is a deficit of effective therapies for wound healing and tissue regeneration. Research performed using animal wound models allows for a better understanding of this complex process, searching for compounds with pro-regenerative properties, and assessing their efficacy and safety. Unfortunately, the lack of adequate preclinical models proves to be an issue as no animal...