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Search results for: George Hojer
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Transcriptomics in Toxicogenomics, Part II: Preprocessing and Differential Expression Analysis for High Quality Data
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Transcriptomics in Toxicogenomics, Part I: Experimental Design, Technologies, Publicly Available Data, and Regulatory Aspects
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A survey on network resiliency methodologies against weather-based disruptions
PublicationDue to the increasing dependence on network services of our society, research has recently been concentrating on enhancing traditional protection strategies to withstand large-scale failures, as in case of disaster events. The recently-formed EU-funded RECODIS project aims at coordinating and fostering research collaboration in Europe on disaster resiliency in communication networks. In particular, the Working Group (WG) 2 of the...
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Analiza niszczącego oddziaływania wody i mrozu na mieszanki mineralno-asfaltowe.
PublicationNiniejsza praca doktorska dotyczy zniszczeń nawierzchni asfaltowych powodowanych oddziaływaniem wody oraz łącznie wody i mrozu. Woda i mróz wpływa na osłabienie kohezji mieszanki i adhezji asfaltu do kruszywa, dąży do odmycia otoczki asfaltu z powierzchni kruszywa, prowadząc do obniżenia wytrzymałości mieszanki i degradacji nawierzchni.Na podstawie studiów literatury autor przedstawił istotę adhezji asfaltu do kruszywa, teorie...
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Splice variants of mitofusin 2 shape the endoplasmic reticulum and tether it to mitochondria
PublicationIn eukaryotic cells, different organelles interact at membrane contact sites stabilized by tethers. Mitochondrial mitofusin 2 (MFN2) acts as a membrane tether that interacts with an unknown partner on the endoplasmic reticulum (ER). In this work, we identified the MFN2 splice variant ERMIT2 as the ER tethering partner of MFN2. Splicing of MFN2 produced ERMIT2 and ERMIN2, two ER-specific variants. ERMIN2 regulated ER morphology,...
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Inhibitor kinazy Brutona u chorych z nawrotowym lub opornym na leczenie chłoniakiem z komórek płaszcza – wyniki międzynarodowego, wieloośrodkowego, badania II fazy z ibrutynibem (PCI-32765) – EHA Encore
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CCDC151 Mutations Cause Primary Ciliary Dyskinesia by Disruption of the Outer Dynein Arm Docking Complex Formation
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Climatology of Transient Luminous Events and Lightning Observed Above Europe and the Mediterranean Sea
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Opposing Age-Related Trends in Absolute and Relative Risk of Adverse Health Outcomes Associated With Out-of-Office Blood Pressure
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Myeloperoxidase Modulates Inflammation in Generalized Pustular Psoriasis and Additional Rare Pustular Skin Diseases
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POEMS Syndrome: Real World Experience in Diagnosis and Systemic Therapy - 108 Patients Multicenter Analysis
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Targeting BTK with Ibrutinib in Relapsed or Refractory Mantle-Cell Lymphoma
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Impacts of salvage logging on biodiversity: A meta-analysis
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Sequence-dependent structural properties of B-DNA: what have we learned in 40 years?
PublicationThe structure of B-DNA, the physiological form of the DNA molecule, has been a central topic in biology, chemistry and physics. Far from uniform and rigid, the double helix was revealed as a flexible and structurally polymorphic molecule. Conformational changes that lead to local and global changes in the helix geometry are mediated by a complex choreography of base and backbone rearrangements affecting the ability of the B-DNA...
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Instytucje demokracji bezpośredniej, partycypacyjnej i deliberacyjnej w Gdańsku od 2010 roku
PublicationTematem tej pracy doktorskiej jest studium przypadku stanu demokracji w Gdańsku. Miasto Gdańsk jest uważane jako jedno z najbardziej demokratycznych miast w Polsce, jednak czy to założenie pokrywa się z faktami? Analiza Autora rozprawy doktorskiej jest skupiona na instytucjach demokratycznych na poziomie lokalnym, ze szczególnym uwzględnieniem obywatelskiej inicjatywy uchwałodawczej jako instrumentu...
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Appropriate Shocks and Mortality in Patients With Versus Without Diabetes With Prophylactic Implantable Cardioverter Defibrillators
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Time Projection Chamber (TPC) detectors for nuclear astrophysics studies with gamma beams
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Progress in upscalingMiscanthusbiomass production for the European bio-economy with seed-based hybrids
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2018 ESC/ESH Guidelines for the management of arterial hypertension
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Facilitating free travel in the Schengen area—A position paper by the European Association for Biometrics
PublicationDue to migration, terror-threats and the viral pandemic, various EU member states have re-established internal border control or even closed their borders. European Association for Biometrics (EAB), a non-profit organisation, solicited the views of its members on ways which biometric technologies and services may be used to help with re-establishing open borders within the Schengen area while at the same time mitigating any adverse...
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An analysis and evaluation of the WeFold collaborative for protein structure prediction and its pipelines in CASP11 and CASP12
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Prospective Observational Study on acute Appendicitis Worldwide (POSAW)
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Architektura a dekonstrukcja. Przypadek Petera Eisenmana i Bernarda Tschumiego
PublicationArchitecture and Deconstruction Case of Peter Eisenman and Bernard Tschumi Introduction Towards deconstruction in architecture Intensive relations between philosophical deconstruction and architecture, which were present in the late 1980s and early 1990s, belong to the past and therefore may be described from a greater than...
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Clinical effectiveness of primary prevention implantable cardioverter-defibrillators: results of the EU-CERT-ICD controlled multicentre cohort study
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Exploring the cost-effectiveness of high versus low perioperative fraction of inspired oxygen in the prevention of surgical site infections among abdominal surgery patients in three low- and middle-income countries
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Blood pressure and low-density lipoprotein-cholesterol lowering for prevention of strokes and cognitive decline
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Blood pressure and LDL-cholesterol targets for prevention of recurrent strokes and cognitive decline in the hypertensive patient
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Continuation of the ESH-CHL-SHOT trial after publication of the SPRINT
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The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through #INPST hashtag analysis
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Physiological parameters for Prognosis in Abdominal Sepsis (PIPAS) Study: a WSES observational study
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ZMYND10 Is Mutated in Primary Ciliary Dyskinesia and Interacts with LRRC6
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The ChoCO-W prospective observational global study: Does COVID-19 increase gangrenous cholecystitis?
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Country‐level and individual‐level predictors of men's support for gender equality in 42 countries
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Long-term safety and efficacy of benralizumab in patients with severe, uncontrolled asthma: 1-year results from the BORA phase 3 extension trial
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Surgeons’ practice and preferences for the anal fissure treatment: results from an international survey
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Diversity and ethics in trauma and acute care surgery teams: results from an international survey
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Handling of the Covid-19 Pandemic and Its Effects on Bariatric Surgical Practice: Analysis of GENEVA Study Database
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10Kin1day: A Bottom-Up Neuroimaging Initiative
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10Kin1day: A bottom-up neuroimaging initiative
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Infected pancreatic necrosis: outcomes and clinical predictors of mortality. A post hoc analysis of the MANCTRA-1 international study
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Blind prediction of homo‐ and hetero‐protein complexes: The CASP13‐CAPRI experiment
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Prediction of protein assemblies, the next frontier: The CASP14‐CAPRI experiment
PublicationWe present the results for CAPRI Round 50, the 4th joint CASP-CAPRI protein assembly prediction challenge. The Round comprised a total of 12 targets, including 6 dimers, 3 trimers, and 3 higher-order oligomers. Four of these were easy targets, for which good structural templates were available either for the full assembly, or for the main interfaces (of the higher-order oligomers). Eight were difficult targets for which only distantly...
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Elective surgery system strengthening: development, measurement, and validation of the surgical preparedness index across 1632 hospitals in 119 countries
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Impact of AlphaFold on structure prediction of protein complexes: The CASP15‐CAPRI experiment
PublicationWe present the results for CAPRI Round 54, the 5th joint CASP-CAPRI protein assembly prediction challenge. The Round offered 37 targets, including 14 homodimers, 3 homo-trimers, 13 heterodimers including 3 antibody–antigen complexes, and 7 large assemblies. On average 70 CASP and CAPRI predictor groups, including more than 20 automatics servers, submitted models for each target. A total of 21 941 models submitted by these groups...
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Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study
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Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries
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Correction: Surgeons’ perspectives on artificial intelligence to support clinical decision-making in trauma and emergency contexts: results from an international survey
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Surgeons’ perspectives on artificial intelligence to support clinical decision-making in trauma and emergency contexts: results from an international survey
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coMpliAnce with evideNce-based cliniCal guidelines in the managemenT of acute biliaRy pancreAtitis): The MANCTRA-1 international audit
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Two years later: Is the SARS-CoV-2 pandemic still having an impact on emergency surgery? An international cross-sectional survey among WSES members
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