Search results for: bialaczka l1210

• Leukemiogeneza oraz współczesne metody terapii przeciwnowotworowych na przykładzie ostrej białaczki szpikowej - AML

  Publication

  • J. J. Lica
  • M. Misiak
  • A. Składanowski

  - Year 2015

  Nie dotyczy

• Synthesis and biological evaluation of 2,7-Dihydro-3H-dibenzo[de,h]cinnoli- ne-3,7-done derivatives a novel group of anticancer agents active on a multidrug resistance cell line.

  Publication

  • B. Stefańska
  • M. Arciemiuk
  • M. Bontemps-Gracz
  • M. Dzieduszycka
  • A. Kupiec
  • S. Martelli
  • E. Borowski

  - IEEE TRANSACTIONS ON SIGNAL PROCESSING - Year 2003

  Zsyntezowano serię pochodnych pirydazonu z jednym lub dwoma łańcuchami bocznymi w różnych pozycjach chromoforu tetracyklicznego. Związki wykazały aktywność cytoksyczną na mysią białaczkę L1210 i ludzką k562 oraz na linii komórkowej oporności krzyżowej MDR (k562/DX). Dwa najbardziej aktywne związki przetestowano in vivo na mysiej białaczce P388. Wykazały one aktywność przeciwnowotworową porównywalną z aktywnością Mitoxantronu.

• Czy galusan epigallokatechiny może być skutecznym polifenolem w terapii skojarzonej z etopozydem w leczeniu przewlekłej białaczki szpikowej?

  Publication

  • A. Cierniak
  • M. Skubal
  • M. Kalemba-Drożdż

  - Państwo i Społeczeństwo - Year 2018

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• Ochrana před úrazem elektrickým proudem při použití proudových chráničů v obvodech s měniči frekvence

  Publication

  • S. Czapp

  - elektro.info - Year 2007

  Obwody zawierające przemienniki częstotliwości charakteryzują się tym, że kształt prądu ziemnozwarciowego zależy od miejsca zwarcia. Prądy ziemnozwarciowe mogą mieć różną częstotliwość oraz być mocno odkształcone, a także, w zależności od zastosowanego układu prostownikowego, mogą być jednokierunkowe o małym lub dużym tętnieniu. Kształt i częstotliwość prądu znacząco wpływa na poprawne działanie wyłączników różnicowoprądowych....

• Sequential induction of mitotic catastrophe followed by apoptosis in human leukemia MOLT4 cells by imidazoacridinone C-1311

  Publication

  • A. Skwarska
  • E. Augustin
  • J. Konopa

  - APOPTOSIS - Year 2007

  Wykazano, że pochodna imidazoakrydonu C-1311 indukuje zahamowanie progresji komórek MOLT4 w fazie G2M cyklu życiowego. Podwyższona ekspresja fosfoepitopu MPM-2 przy jednoczesnym zaniku ufosforylowanej formy Tyr15-cdc2 wskazywała, iż komórki początkowo zablokowane w fazie G2 przechodziły do mitozy. Jednocześnie na skutek nieprawidłowego przebiegu mitozy komórki ulegały katastrofie mitotycznej. Analiza biochenicznych markerów apoptozy...

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• Induction of G2/M phase arrest and apoptosis of human leukemia cells by potent antitumor triazoloacridinone C-1305

  Publication

  • E. Augustin
  • A. Moś-Rompa
  • A. Skwarska
  • J. M. Witkowski
  • J. Konopa

  - BIOCHEMICAL PHARMACOLOGY - Year 2006

  Wykazaliśmy, że pochodna triazoloakrydonu C-1305 w stężeniach biologicznie istotnych indukuje blok cyklu komórkowego w fazie G2/M i apoptozę w komórkach białaczek ludzkich MOLT4 i HL60. Zjawisko apoptozy zostało określone na podstawie charakterystycznych zmian morfologicznych jak i biochemicznych tj. fragmentacji DNA, aktywacji kaspazy 3, cięcia PARP, spadku potencjału mitochondrialnego i ATP oraz eksternalizacji fosfatydyloseryny.

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• Synthesis and antiproliferative activity of conjugates of adenosine with muramyl dipeptide and nor-muramyl dipeptide derivatives

  Publication

  • M. Samsel
  • K. Dzierzbicka
  • P. Trzonkowski

  - BIOORGANIC & MEDICINAL CHEMISTRY LETTERS - Year 2014

  We synthesized a series of MDP(D,D) and nor-MDP(D,D) derivatives conjugated with adenosine through a spacer as potential immunosuppressants. New conjugates were evaluated on two leukemia cell lines (Jurkat and L1210) and PBMC from healthy donors.

• Hairy cell leukemia, NOS - Male, 61 - Tissue image [6270730022336371]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Hairy cell leukemia, NOS - Male, 61 - Tissue image [6270730022336731]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Hairy cell leukemia, NOS - Male, 61 - Tissue image [6270730022333851]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Hairy cell leukemia, NOS - Male, 61 - Tissue image [6270730022332291]

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  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Hairy cell leukemia, NOS - Male, 61 - Tissue image [6270730022333601]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Hairy cell leukemia, NOS - Male, 61 - Tissue image [7040247104966231]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Hairy cell leukemia, NOS - Male, 61 - Tissue image [627073002233891]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Hairy cell leukemia, NOS - Male, 61 - Tissue image [6270730022338691]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Hairy cell leukemia, NOS - Male, 61 - Tissue image [6270730022339761]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Hairy cell leukemia, NOS - Male, 61 - Tissue image [6270730022335621]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Hairy cell leukemia, NOS - Male, 61 - Tissue image [6270730022333721]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Hairy cell leukemia, NOS - Male, 61 - Tissue image [6270730022331211]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Hairy cell leukemia, NOS - Male, 61 - Tissue image [6270730022337551]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Dietary intervention with beetroot juice during doxorubicin cancer chemotherapy in vivo reduces markers of oxidative stress

  Publication

  • J. Łukowicz
  • G. Peszyńska-Sularz
  • A. Cieślak
  • A. Piasek
  • M. Janicka
  • A. Kot-Wasik
  • S. Popadiuk
  • W. Grajek
  • A. Bartoszek-Pączkowska

  - Acta Biochimica Polonica - Year 2012

  Cancer chemotherapy with doxorubicin, despite high antitumor activity and broad spectrum of this drug, is on decline due to toxic side effects. The clinical efficacy of anthracyclines have continuously prompted the search for new adjuvants to alleviate undesirable side toxicity incurred by this group of cytostatics. The recent approaches involve the application of synthetic or purified natural antioxidants in combination with doxorubicin...

• Precursor T-cell lymphoblastic leukemia - Male, 4 - Tissue image [6030730027632101]

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Precursor T-cell lymphoblastic leukemia - Male, 4 - Tissue image [6030730027631481]

  Open Research Data

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Precursor T-cell lymphoblastic leukemia - Male, 4 - Tissue image [6030730027633261]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Precursor T-cell lymphoblastic leukemia - Male, 4 - Tissue image [7040247104964671]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Precursor T-cell lymphoblastic leukemia - Male, 4 - Tissue image [6030730027632941]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Antioxidative properties of some vegetable products traditional for diets in Central European diet - short report

  Publication

  • A. Bartoszek-Pączkowska
  • J. Forc
  • J. Grześkowiak

  - Polish Journal of Food and Nutrition Sciences - Year 2002

  Badania nad przeciwutleniającymi właściwościami wybranych warzywnych produktów spożywczych prowadzone były przy użyciu testu ABTS i testu kometkowego. Wykazano, że spośród badanych produktów najwyższą aktywność przeciwutleniającą wykazywał koncentrat buraczany oraz kiszona kapusta. Sok z kiszonej kapusty w badaniach przy użyciu komórek białaczki i testu kometkowego miał zdolność ochrony komórek przed aktywnymi formami tlenu.

• B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma - Male, 56 - Tissue image [4120730022886891]

  Open Research Data

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma - Male, 56 - Tissue image [6270730022339311]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Precursor T-cell lymphoblastic leukemia - Male, 4 - Tissue image [6030730027633151]

  Open Research Data

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  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEART, MEDIASTINUM, AND PLEURA tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Precursor T-cell lymphoblastic leukemia - Male, 4 - Tissue image [6030730027632371]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEART, MEDIASTINUM, AND PLEURA tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Dietary intervention with red beet juice ameliorates side effects resulting from oxidative stress during cancer chemotherapy with doxorubicin

  Publication

  • J. Paradziej-Łukowicz
  • G. Peszyńska-Sularz
  • A. Cieślak
  • A. Piasek
  • S. Popadiuk
  • W. Grajek
  • A. Bartoszek-Pączkowska

  - Acta Biochimica Polonica - Year 2006

  Chemoterapia nowotworów wiąże się ze stymulacją stresu oksydacyjnego, wywołującego niekorzystne efekty uboczne w organizmie. Panuje pogląd, że wprowadzenie do terapii przeciwutleniaczy może te niekorzystne efekty uboczne zmniejszyć. W naszych badaniach jako źródło utleniaczy wykorzystaliśmy sok z buraka ćwikłowego. Pokazaliśmy, że jego zastosowanie w kombinacji z lekiem przeciwnowotworowym doksorubicyną znacznie poprawia efekty...

• Czy stan oznakowania dróg samorządowych ma wpływ na bezpieczeństwo ruchu drogowego?

  Publication

  • O. Białczak- Koprowska
  • A. Gardocka
  • J. Wachnicka

  - Drogownictwo - Year 2020

  Głównym celem artykułu była analiza stanu oznakowania dróg wojewódzkich oraz bezpieczeństwa ruchu drogowego na dwóch drogach wojewódzkich zlokalizowanych w województwie pomorskim, na których nastąpił wzrost wypadków w latach 2015-2017 w stosunku do lat 2012-2014. Badanie rozpoczęto od przeanalizowania stanu bezpieczeństwa ruchu drogowego bazując na danych o wypadkach. Następnie udano się na wizję lokalną, gdzie za pomocą oględzin...

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• Precursor T-cell lymphoblastic leukemia - Male, 4 - Tissue image [7040247104956811]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEART, MEDIASTINUM, AND PLEURA tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Precursor T-cell lymphoblastic leukemia - Male, 4 - Tissue image [6030730027633471]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEART, MEDIASTINUM, AND PLEURA tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Precursor T-cell lymphoblastic leukemia - Male, 4 - Tissue image [6030730027635021]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEART, MEDIASTINUM, AND PLEURA tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Precursor T-cell lymphoblastic leukemia - Male, 4 - Tissue image [6030730027631611]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEART, MEDIASTINUM, AND PLEURA tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Precursor T-cell lymphoblastic leukemia - Male, 4 - Tissue image [6030730027635751]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEART, MEDIASTINUM, AND PLEURA tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Precursor T-cell lymphoblastic leukemia - Male, 4 - Tissue image [6030730027643621]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Precursor T-cell lymphoblastic leukemia - Male, 4 - Tissue image [6030730027647811]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Precursor T-cell lymphoblastic leukemia - Male, 4 - Tissue image [6030730027645771]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma - Male, 63 - Tissue image [7060729599325631]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Precursor T-cell lymphoblastic leukemia - Male, 4 - Tissue image [6030730027642571]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Precursor T-cell lymphoblastic leukemia - Male, 4 - Tissue image [6030730027645031]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Precursor T-cell lymphoblastic leukemia - Male, 4 - Tissue image [603073002764851]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Precursor T-cell lymphoblastic leukemia - Male, 4 - Tissue image [6030730027646601]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Precursor T-cell lymphoblastic leukemia - Male, 4 - Tissue image [6030730027647141]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma - Male, 63 - Tissue image [7060729599325431]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Precursor T-cell lymphoblastic leukemia - Male, 4 - Tissue image [6030730027644741]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma - Male, 63 - Tissue image [706072959932701]

  Open Research Data

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.