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Search results for: antifungal target
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Exchange-Traded Funds in Europe
PublicationExchange-Traded Funds in Europe provides a single point of reference on a diverse set of regional ETF markets, illuminating the roles ETFs can play in risk mitigation and speculation. Combining empirical data with models and case studies, the authors use diffusion models and panel/country-specific regressions—as well as graphical and descriptive analyses— to show how ETFs are more than conventional, passive investments. With new...
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Podhalańska Państwowa Uczelnia Zawodowa w Nowym Targu
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Rapid and Reliable Re-Design of Miniaturized Microwave Passives by Means of Concurrent Parameter Scaling and Intermittent Local Tuning
PublicationRe-design of microwave passive components for the assumed operating frequencies or substrate parameters is an important yet a tedious process. It requires simultaneous tuning of relevant circuit variables, often over broad ranges thereof, to ensure satisfactory performance of the system. If the operating conditions at the available design are distant from the intended ones, local optimization is typically insufficient, whereas...
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Aleksander Jarzębowicz dr inż.
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CDK9: Therapeutic Perspective in HCC Therapy
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Current Challenges in Targeting Tumor Desmoplasia to Improve the Efficacy of Immunotherapy
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Novel anticancer strategy aimed at targeting shelterin complexes by the induction of structural changes in telomeric DNA: hitting two birds with one stone.
PublicationThe ends of chromosomes in mammals are composed of telomeric DNA containing TTAGGG repeats, which bind specific proteins called shelterins. This telomeric DNA together with shelterins form a cap that protects the ends of chromosomes from being recognized as sites of DNA damage and from chromosomal fusions. Many very successful antitumor drugs used in the treatment of cancer patients bind to DNA, some of them with a prominent sequence...
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Market Analysis 2022/23
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Market Analysis 2023/24
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Development of a solventless stir bar sorptive extraction/thermal desorption large volume injection capillary gas chromatographic-mass spectrometric method for ultra-trace determination of pyrethroids pesticides in river and tap water samples
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Qualitative methods for market research
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Foundations of Capital Market Analysis
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Foundations of Capital Market Analysis
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E-experiments in physics. Proper business process management, collaborative development process and project management guidance – remedy for avoiding the main IT project’s failure
PublicationOnly a few of learning aids and simulations of physical phenomena allow for building interactive experiments; experiments similar to those that should be conducted in physics laboratories at schools. Group of staff from Gdansk University of Technology decided to fill this market niche by designing and constructing a set of virtual experiments – so called e-experiments. To avoid common problems that a lot of IT products brought...
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Targi Pracy GUT International Career Day 2020
EventsBiuro Karier PG oraz Dział Międzynarodowej Współpracy Akademickiej zapraszają na Targi Pracy – GUT International Career Day. Zaproszone firmy przedstawią oferty pracy, praktyk i staży.
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„PRACODAWCY DLA ZiE” - Wydziałowe Targi Pracy on-line
EventsZapraszamy 18 marca (czwarte) na wydziałowe targi pracy! Możliwość porozmawiania z przedstawicielami firm oraz uczestniczenia w webinariach. Spotkania odbywają się on-line.
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In silico approaches for better understanding cysteine cathepsin-glycosaminoglycan interactions
PublicationCysteine cathepsins constitute the largest cathepsin family, with 11 proteases in human that are present primarily within acidic endosomal and lysosomal compartments. They are involved in the turnover of intracellular and extracellular proteins. They are synthesized as inactive procathepsins that are converted to mature active forms. Cathepsins play important roles in physiological and pathological processes and, therefore, receive...
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Rhodotorulic Acid and its Derivatives: Synthesis, Properties, and Applications
PublicationSiderophores are low molecular weight compounds produced by microorganisms to scavenge iron in iron-deficient environments. Rhodotorulic acid (RA), a natural hydroxamate siderophore, plays a vital role in iron acquisition for fungi and bacteria. As the simplest natural hydroxamate siderophore, RA exhibits a high affinity for ferric ions, enabling it to form stable complexes that facilitate iron uptake and transport within microorganisms....
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Organic semiconductor rubrene thin films deposited by pulsed laser evaporation of solidified solutions
PublicationOrganic semiconductor rubrene (C42H28) belongs to most preferred spintronic materials because of the high charge carrier mobility up to 40 cm2(V·s)-1. However, the fabrication of a defect-free, polycrystalline rubrene for spintronic applications represents a difficult task. We report preparation and properties of rubrene thin films deposited by pulsed laser evaporation of solidified solutions. Samples of rubrene dissolved in aromatic...
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The Effect of Sterols on Amphotericin B Self-Aggregation in a Lipid Bilayer as Revealed by Free Energy Simulations
PublicationAmphotericin B (AmB) is an effective but toxic antifungal drug, known to increase the permeability of the cell membrane, presumably by assembling into transmembrane pores in a sterol-dependent manner. The aggregation of AmB molecules in a phospholipid bilayer is, thus, crucial for the drug’s activity. To provide an insight into the molecular nature of this process, here, we report an atomistic molecular dynamics simulation study...
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EXCHANGE TRADED COMMODITIES AS A CATEGORY OF INNOVATIVE PRODUCTS ON EUROPEAN FINANCIAL MARKETS
PublicationThe article presents the main features of one category of innovative financial products – exchange traded commodities (ETCs) and results of the analysis of the European market for ETCs. ETCs are products listed and traded on the stock exchanges and they offer investors returns based on various assets (commodities or currencies). In contrast with the most widely recognized exchange traded funds (ETFs), ETCs are structured as debt...
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Maria Jastrzębska dr hab.
PeopleMaria Jastrzębska is an employee of the Department of Finance. She is the author of over 170 publications, including 8 monographs - Financial Management of Municipalities. Theoretical aspects; Budgetary policy of local government units; Debt management of local government units; Finances of local government units; Risk management in the activity of local government units with special consideration of catastrophic risk (co-author...
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Ireneusz Kreja dr hab. inż.
PeopleGraduated from the mathematical class at the Nicolaus Copernicus High School in Gdańsk (1974). Master of Sciences in Civil Engineering after studies at Gdansk University of Technology (GUT), Poland (1974-1979). Since 1979 became an employee of the GUT. In 1989 earned a Ph.D. degree in Civil Engineering (with grade "Summa cum Laude") from the GUT. In 2008 obtained a D. Sc. (Habilitation) degree in Civil Engineering (with grade...
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Low-energy positron scattering from gas-phase pyrimidine: A quantum treatment of the dynamics and a comparison with experiments
PublicationWe are reporting detailed quantum scattering calculations that describe the diffusion of a beam of low-energy positrons interacting with the pyrimidine target as a gas-phase partner. The calculations have employed an essentially ab initio model for the short-range correlation interaction and for the electrostatic interaction of an impinging positron and the electron+nuclear structure of the target molecule at its equilibrium geometry.
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eFRADIR: An Enhanced FRAmework for DIsaster Resilience
PublicationThis paper focuses on how to increase the availability of a backbone network with minimal cost. In particular, the new framework focuses on resilience against natural disasters and is an evolution of the FRADIR/FRADIR-II framework. It targets three different directions, namely: network planning, failure modeling, and survivable routing. The steady state network planning is tackled by upgrading a sub-network (a set of links termed...
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Chemia organiczna, kierunek Biotechnologia, ćwiczenia, sem. IV
e-Learning CoursesOmówienie treści prezentowanych na wykładzie. Struktura, otrzymywanie i reaktywność poszczególnych klas związków organicznych. Uzupełnienie zajęć prowadzonych za pośrednictwem Skype, link do grupy: https://join.skype.com/mBDeYRzJz6Rq
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Tagged images with LEGO bricks - Bricks Sloped
Open Research DataThe set contains images of LEGO bricks (from Bricks Sloped category). The images were prepared for training neural network for recognition and labeling of LEGO bricks. The images contain one brick each. The images were taken from different sides by handheld camera hovering over the bricks lying on a white, non reflective surface.
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Tagged images with LEGO bricks - Windscreens and Fuselage
Open Research DataThe set contains images of LEGO bricks (from Windscreens and Fuselage category). The images were prepared for training neural network for recognition and labeling of LEGO bricks. The images contain one brick each. The images were taken from different sides by handheld camera hovering over the bricks lying on a white, non reflective surface.
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Tagged images with LEGO bricks - Bricks Special
Open Research DataThe set contains images of LEGO bricks (from Bricks Special category). The images were prepared for training neural network for recognition and labeling of LEGO bricks. The images contain one brick each. The images were taken from different sides by handheld camera hovering over the bricks lying on a white, non reflective surface.
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Tagged images with LEGO bricks part 2
Open Research DataThe data set conatins tagged images conatining LEGO bricks used for traning LEGO bricks detecting network. The images contain random number of the same LEGO bricks on white background. Only the whole bricks are labeled.
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Tagged images with LEGO bricks - Technic Beams
Open Research DataThe set contains images of LEGO bricks (from Technic Beams category). The images were prepared for training neural network for recognition and labeling of LEGO bricks. The images contain one brick each. The images were taken from different sides by handheld camera hovering over the bricks lying on a white, non reflective surface.
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Tagged images with LEGO bricks - Technic Pins
Open Research DataThe set contains images of LEGO bricks (from Technic Pins category). The images were prepared for training neural network for recognition and labeling of LEGO bricks. The images contain one brick each. The images were taken from different sides by handheld camera hovering over the bricks lying on a white, non reflective surface.
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Tagged images with LEGO bricks - Minifig Accessories
Open Research DataThe set contains images of LEGO bricks (from Minifig Accessories category). The images were prepared for training neural network for recognition and labeling of LEGO bricks. The images contain one brick each. The images were taken from different sides by handheld camera hovering over the bricks lying on a white, non reflective surface.
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Tagged images with LEGO bricks - Technic Panels
Open Research DataThe set contains images of LEGO bricks (from Technic Panels category). The images were prepared for training neural network for recognition and labeling of LEGO bricks. The images contain one brick each. The images were taken from different sides by handheld camera hovering over the bricks lying on a white, non reflective surface.
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Tagged images with LEGO bricks - Technic Bricks
Open Research DataThe set contains images of LEGO bricks (from Technic Bricks category). The images were prepared for training neural network for recognition and labeling of LEGO bricks. The images contain one brick each. The images were taken from different sides by handheld camera hovering over the bricks lying on a white, non reflective surface.
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Tagged images with LEGO bricks - Technic Gears
Open Research DataThe set contains images of LEGO bricks (from Technic Gears category). The images were prepared for training neural network for recognition and labeling of LEGO bricks. The images contain one brick each. The images were taken from different sides by handheld camera hovering over the bricks lying on a white, non reflective surface.
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Tagged images with LEGO bricks - Technic Bushes
Open Research DataThe set contains images of LEGO bricks (from Technic Bushes category). The images were prepared for training neural network for recognition and labeling of LEGO bricks. The images contain one brick each. The images were taken from different sides by handheld camera hovering over the bricks lying on a white, non reflective surface.
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Tagged images with LEGO bricks - Plates Angled
Open Research DataThe set contains images of LEGO bricks (from Plates Angled category). The images were prepared for training neural network for recognition and labeling of LEGO bricks. The images contain one brick each. The images were taken from different sides by handheld camera hovering over the bricks lying on a white, non reflective surface.
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Tagged images with LEGO bricks - Windows and Doors
Open Research DataThe set contains images of LEGO bricks (from Windows and Doors category). The images were prepared for training neural network for recognition and labeling of LEGO bricks. The images contain one brick each. The images were taken from different sides by handheld camera hovering over the bricks lying on a white, non reflective surface.
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Tagged images with LEGO bricks - Plates Special
Open Research DataThe set contains images of LEGO bricks (from Plates Special category). The images were prepared for training neural network for recognition and labeling of LEGO bricks. The images contain one brick each. The images were taken from different sides by handheld camera hovering over the bricks lying on a white, non reflective surface.
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Tagged images with LEGO bricks - Technic Connectors
Open Research DataThe set contains images of LEGO bricks (from Technic Connectors category). The images were prepared for training neural network for recognition and labeling of LEGO bricks. The images contain one brick each. The images were taken from different sides by handheld camera hovering over the bricks lying on a white, non reflective surface.
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Tagged images with LEGO bricks - Bricks Curved
Open Research DataThe set contains images of LEGO bricks (from Bricks Curved category). The images were prepared for training neural network for recognition and labeling of LEGO bricks. The images contain one brick each. The images were taken from different sides by handheld camera hovering over the bricks lying on a white, non reflective surface.
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Tagged images with LEGO bricks - Tiles Special
Open Research DataThe set contains images of LEGO bricks (from Tiles Special category). The images were prepared for training neural network for recognition and labeling of LEGO bricks. The images contain one brick each. The images were taken from different sides by handheld camera hovering over the bricks lying on a white, non reflective surface.
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Tagged images with LEGO bricks - Transportation - Land
Open Research DataThe set contains images of LEGO bricks (from Transportation - Land category). The images were prepared for training neural network for recognition and labeling of LEGO bricks. The images contain one brick each. The images were taken from different sides by handheld camera hovering over the bricks lying on a white, non reflective surface.
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Tagged images with LEGO bricks - Bricks Wedged
Open Research DataThe set contains images of LEGO bricks (from Bricks Wedged category). The images were prepared for training neural network for recognition and labeling of LEGO bricks. The images contain one brick each. The images were taken from different sides by handheld camera hovering over the bricks lying on a white, non reflective surface.
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Tagged images with LEGO bricks - Technic Axles
Open Research DataThe set contains images of LEGO bricks (from Technic Axles category). The images were prepared for training neural network for recognition and labeling of LEGO bricks. The images contain one brick each. The images were taken from different sides by handheld camera hovering over the bricks lying on a white, non reflective surface.
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Tagged images with LEGO bricks - Technic Special
Open Research DataThe set contains images of LEGO bricks (from Technic Special category). The images were prepared for training neural network for recognition and labeling of LEGO bricks. The images contain one brick each. The images were taken from different sides by handheld camera hovering over the bricks lying on a white, non reflective surface.
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Tagged images with LEGO bricks - Plants and Animals
Open Research DataThe set contains images of LEGO bricks (from Plants and Animals category). The images were prepared for training neural network for recognition and labeling of LEGO bricks. The images contain one brick each. The images were taken from different sides by handheld camera hovering over the bricks lying on a white, non reflective surface.
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The largest companies in the TSL industry in Poland in 2011
Open Research DataThe data contained in the dataset shows that the most successful transport, forwarding and logistics company in Poland in 2011 was PKP CARGO S.A. The company is the largest carrier in the country, while in the European Union it ranks second in terms of freight transport.
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Piotr Figura dr inż.
PeoplePiotr Figura is employed as an assistant professor at the Department of Finance at the Faculty of Management and Economics, Gdansk University of Technology. He is a member of Commission for the Verification of Learning Outcomes, as well as an academic reviewer of the Central Exemination Booard. He is the author or co-author of several scientific monographs including: Standard financial indicators for stock enterprises; Classical...