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Search results for: GENETIC PREDISPOSITION
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Genetic and pharmacologic proteasome augmentation ameliorates Alzheimer’s-like pathology in mouse and fly APP overexpression models
PublicationThe proteasome has key roles in neuronal proteostasis, including the removal of misfolded and oxidized proteins, presynaptic protein turnover, and synaptic efficacy and plasticity. Proteasome dysfunction is a prominent feature of Alzheimer’s disease (AD). We show that prevention of proteasome dysfunction by genetic manipulation delays mortality, cell death, and cognitive deficits in fly and cell culture AD models. We developed...
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Genetic and pharmacologic proteasome augmentation ameliorates Alzheimer’s-like pathology in mouse and fly APP overexpression models
PublicationThe proteasome has key roles in neuronal proteostasis, including the removal of misfolded and oxidized proteins, presynaptic protein turnover, and synaptic efficacy and plasticity. Proteasome dysfunction is a prominent feature of Alzheimer’s disease (AD). We show that prevention of proteasome dysfunction by genetic manipulation delays mortality, cell death, and cognitive deficits in fly and cell culture AD models. We developed...
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Hierarchical Estimation of Human Upper Body Based on 2D Observation Utilizing Evolutionary Programming and 'Genetic Memory'
PublicationNew method of the human body pose estimation based on single camera 2D observation is presented. It employs 3D model of the human body, and genetic algorithm combined with annealed particle filter for searching the global optimum of model state, best matching the object's 2D observation. Additionally, motion cost metric is employed, considering current pose and history of the body movement, favouring the estimates with the lowest...
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Quantitative Analysis of Biofilm Formed on Vascular Prostheses by Staphylococcus Epidermidis with Different ica and aap Genetic Status
PublicationOBJECTIVES: This study aims to examine biofilm formed on vascular prostheses by Staphylococcus epidermidis with different ica and aap genetic status, and to evaluate the effect of antibiotic-modified prostheses on bacterial colonization. METHODS: Biofilm formation was determined using fluorescence microscopy imaging. Quantitative analysis was conducted using the biofilm coverage ratio (BCR) calculations. RESULTS: Our investigations...
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BMC Medical Genetics
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Conservation Genetics Resources
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Circulation. Cardiovascular Genetics
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Journal of Pediatric Genetics
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GENETICS AND MOLECULAR BIOLOGY
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Application of Clinical Genetics
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International Journal of Genetics
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Genetics Research International
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GENETICS SELECTION EVOLUTION
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Journal of Community Genetics
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GENETICS AND MOLECULAR RESEARCH
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Genetics in the Third Millennium
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HUMAN MOLECULAR GENETICS
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Ecological Genetics and Genomics
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Annual Review of Genetics
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KOREAN JOURNAL OF GENETICS
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Journal of Genetics and Genomics
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MOLECULAR GENETICS AND METABOLISM
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JOURNAL OF MEDICAL GENETICS
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Genetics of Aquatic Organisms
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JOURNAL OF HUMAN GENETICS
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Global Medical Genetics
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Animal Science and Genetics
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NATURE REVIEWS GENETICS
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MOLECULAR GENETICS AND GENOMICS
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NEW GENETICS AND SOCIETY
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Tree Genetics & Genomes
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THEORETICAL AND APPLIED GENETICS
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Molecular Genetics & Genomic Medicine
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Morphological, genetic, chemical and ecophysiological characterisation of two Microcystis aeruginosa isolates from the Vistula Lagoon, southern Baltic
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Influence of genetic background and oxidative stress response on risk of mandibular osteoradionecrosis after radiotherapy of head and neck cancer
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Genetic solver of optimization task of mpc for optimizing control of integrated quantity and quality in drinking water distribution systems
PublicationPredykcyjne sterowanie zintegrowana jakością i ilością wody pitnej umożliwia uzyskanie lepszej jakości sterowania niż w przypadku innych metod. Niestety wymaga rozwiązania nieliniowego, niewypukłego problemu optymalizacji. Z tego względu potrzebne jest wykorzystanie specjalizowanego solwera w celu rozwiązania problemu optymalizacji predykcyjnej w wymaganych czasie. W tym artykule przedstawiony jest dedykowany algorytm genetyczny...
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Insight into the microbial and genetic response of anammox biomass to broad range concentrations of different antibiotics: Linking performance and mechanism
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Genetic risk factors influence nighttime blood pressure and related cardiovascular complications in patients with coronary heart disease
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Vitiligo pathogenesis: autoimmune disease, genetic defect, excessive reactive oxygen species, calcium imbalance, or what else?
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Diclofenac Degradation—Enzymes, Genetic Background and Cellular Alterations Triggered in Diclofenac-Metabolizing Strain Pseudomonas moorei KB4
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Genetic variation in C-reactive protein (CRP) gene is associated with retinopathy and hypertension in adolescents with type 1 diabetes
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Genetic diversity of Legionella pcs and pmtA genes and the effect of utilization of choline by Legionella spp. on induction of proinflammatory cytokines
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Prefrontal Dysfunctions and Temperament in Pathological Obesity - the Results of Neuropsychological, TEMPS-A and Genetics Studies
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New oryginal generic technologies: A Polish R&D strategic implementation programme
PublicationPolands's pharmaceutical industry is of great significance to the whole economy. According to Forbs (2 October 2012), the cost of launching a new drug varies from USD 1 to 11 bilion. There is little Chance of a Polish pharmaceutical company developing an original drug due to financial reason.Many research teams in Poland take up research projects aimed at new biologically active compounds. But such an objective has no broader perspective,...
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Modelling and computer animation of geodetic field work
Publication3D modelling of objects is a way of obtaining information, while the visualization of geospatial data is becoming a production task in the scope of surveying. Visualization of geospatial data provides effective tools for analysis information about the land surface, land cover, its features, properties etc. Computer animations, both 2D images and 3D are becoming additional, expected and clear form for presentation results of geodetic...
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Utopian Kinetic Structures and Their Impact on the Contemporary Architecture
PublicationThis paper delves into relationships between twentieth century utopian concepts of movable structures and the kinematic solutions implemented in contemporary architectural projects. The reason for conducting this study is to determine the impact of early architectural conceptions on today's solutions. This paper points out close links that stem from the imagination of artists and architects working in 1960s and 70s and the solutions...
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COMPARATIVE ANALYSIS OF ACTIVE GEODETIC NETWORKS IN POLAND
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AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
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Memetic Computing
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Genetika-Belgrade
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