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Search results for: biochemia
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Nitroreductase reactions of Arabidopsis thaliana thioredoxin reductase
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Quantitative structure–activity relationships in enzymatic single-electron reduction of nitroaromatic explosives: implications for their cytotoxicity
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Excitation energy transport and trapping in concentrated solid solution of flavomononucleotide
PublicationW pracy analizowano bez promienisty transfer energii w stężonych stałych roztworach (folie polimerowe) FMN. W w/w roztworach występują świecące dimery FMN. Pokazano, że jedynie uwzględnienie powrotnego transferu energii pozwala zadowalająco wyjaśnić mechanizm przenoszenia energii w badanych układach.
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Modulation of polyene antibiotics self-association by ions from the hofmeister series
PublicationZbadano wpływ soli z serii hofmeistera na zjawisko samoasocjacji antybiotyku polienowego amfoterycyny B i jego pochodnych. Wykazano, że sole te zmieniając właściwości wody, wpływają istotnie na strukturę roztworów tych antybiotyków. Sole kosmotropowe zmniejszają rozpuszczalność związków, chaotropowe dają efekt przeciwny. Informacja ta jest istotna dla zrozumienia natury toksyczności amfoterycyny B i jej pochodnych.
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Modification of quaternary structure of Candida albicans GlcN-6-P synthase and its desensitization to inhibition by UDP-GlcNAc by site-directed mutagenesis
PublicationSite-directed mutagenesis of the CaGFA1 gene encoding glucosamine-6-phosphate synthase from Candida albicans was performed. Desensitization of the enzyme to inhibition by UDPGlcNAc was achieved upon T487I and H492F substitutions at the UDP-GlcNAc binding site, exchange of D524, S525 and S527 for Ala at the dimer:dimer interface and construction of the tail-lock array (L434R and L460A) at the C-tail region. The first two sets if...
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Carotid Artery Stenting and Blood–Brain Barrier Permeability in Subjects with Chronic Carotid Artery Stenosis
PublicationFailure of the blood-brain barrier (BBB) is a critical event in the development and progression of diseases such as acute ischemic stroke, chronic ischemia or small vessels disease that affect the central nervous system. It is not known whether BBB breakdown in subjects with chronic carotid artery stenosis can be restrained with postoperative recovery of cerebral perfusion. The aim of the study was to assess the short-term effect...
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Journey towards light – evolutionary adaptations of humans, flora and fauna. Guidelines for safe and healthy illumination
PublicationThe paper examines using relatively recent discoveries on how evolution has embedded within all living organisms a natural sensitivity towards their native environment, in particular luminance levels and specific wavelengths of light. The studies conducted so far indicate that lighting installations that are visible after dark impact on humans, flora and fauna and influence our evolutionary dispositions, possibly with negative...
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Innovations in Wastewater Treatment: Harnessing Mathematical Modeling and Computer Simulations with Cutting-Edge Technologies and Advanced Control Systems
PublicationThe wastewater treatment landscape in Central Europe, particularly in Poland, has undergone a profound transformation due to European Union (EU) integration. Fueled by EU funding and rapid technological advancements, wastewater treatment plants (WWTPs) have adopted cutting-edge control methods to adhere to EU Water Framework Directive mandates. WWTPs contend with complexities such as variable flow rates, temperature fluctuations,...
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Weekend Muzeów online na Politechnice Gdańskiej
EventsZapraszamy do udziału w Weekendzie Muzeów – wykładach online, podejmujących aktualne zagadnienia zdrowotne. Transmisja na żywo na kanale YouTube Politechnika Otwarta, z możliwością zadawania pytań prelegentom w komentarz
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City and Urbanity in the Social Discourse
PublicationThe aim of our article is an attempt to present the concept of urbanity that has been shaped throughout centuries along with the development of European civilisation and now entered a new phase of social production of space based on cultural dimensions. The future of the majority of World’s population is connected currently with the urban life with the assumption that qualitative characteristics of life in the 21st century define...