Wyniki wyszukiwania dla: chemioterapia

• Granular cell tumor, NOS - Female, 55 - Tissue image [5060730006981931]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Hodgkin lymphoma, nodular lymphocyte predominant - Male, 32 - Tissue image [7020730007255491]

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  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Hodgkin lymphoma, nodular lymphocyte predominant - Male, 32 - Tissue image [7020730007257491]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Hodgkin lymphoma, nodular lymphocyte predominant - Male, 32 - Tissue image [7020730007258171]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Granular cell tumor, NOS - Female, 55 - Tissue image [5060730006987041]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Hodgkin lymphoma, nodular lymphocyte predominant - Male, 75 - Tissue image [11010630088557841]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Hodgkin lymphoma, nodular lymphocyte predominant - Male, 32 - Tissue image [7020730007253691]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Hodgkin lymphoma, nodular lymphocyte predominant - Male, 75 - Tissue image [6170730026742151]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Hodgkin lymphoma, nodular lymphocyte predominant - Male, 32 - Tissue image [7020730007251081]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Hodgkin lymphoma, nodular lymphocyte predominant - Male, 32 - Tissue image [7020730007251971]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Angiosarcoma - Female, 67 - Tissue image [6140729599017641]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Granular cell tumor, NOS - Female, 55 - Tissue image [5060730006983201]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Angiosarcoma - Female, 67 - Tissue image [614072959901241]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Angiosarcoma - Female, 67 - Tissue image [6140729599018221]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Angiosarcoma - Female, 67 - Tissue image [6140729599015411]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Angiosarcoma - Female, 67 - Tissue image [614072959901651]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

• Modulation of cellular response to anticancer treatment by caffeine:inhibition of cell cycle checkpoints, DNA repair and more

  Publikacja

  • M. Sabisz
  • A. Składanowski

  - CURRENT PHARMACEUTICAL BIOTECHNOLOGY - Rok 2008

  Kofeina i inne metyloksantyny wywołują bardzo różne efekty fizjologiczne w organizmie człowieka. W pracy przedstawiamy, które z tych efektów mogą wpływać na skuteczność terapii przeciwnowotworowych. Kofeina może bezpośrednio wpływać na transport oraz aktywację metaboliczną cząsteczek leków do komórki, poprzez tworzenie kompleksów z lekami zawierającymi układy poliaromatyczne. Kofeina hamuje aktywność kinaz ATM/ATR co prowadzi do...

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• Cykl komórkowy jako cel nowych terapii przeciwnowotworowych

  Publikacja

  • M. Sabisz
  • A. Składanowski

  - Rok 2007

  Niekontrolowana proliferacja jest jedną z podstawowych cech komórek nowotworowych, w związku z czym nowotwór nazywany jest często ''chorobą cyklu komórkowego''. Cykl komórkowy jest regulowany przez system tzw. punktów kontrolnych, których zadaniem jest monitorowanie poprawności przebiegu zdarzeń zachodzących w poszczególnych jego fazach oraz warunkujących rozpoczęcie kolejnej fazy cyklu komórkowego. U większości komórek nowotworowych...

• Glukuronidacja leków przeciwnowotworowych – detoksyfikacja, mechanizm oporności czy sposób na formę proleku?*

  Publikacja

  • A. Mróz
  • Z. Mazerska

  - Postępy Higieny i Medycyny Doświadczalnej - Rok 2015

  Ksenobiotyki podlegają w organizmie biotransformacji I i II fazy, której celem jest ich detoksyfikacja i ułatwienie wydalania. UDP-glukuronylotransferazy (UGT) – enzymy należące do II fazy metabolizmu katalizują przyłączenie kwasu glukuronowego do lipofilowego substratu zawierającego nukleofilową grupę funkcyjną. Nadrodzina UGT składa się z izoenzymów o różnej swoistości substratowej oraz odmiennym profilu ekspresji w poszczególnych tkankach....

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• Therapeutic intervention by the simultaneous inhibition of DNA repair and type I or type II DNA topoisomerases: one strategy, many outcomes

  Publikacja

  • J. Węsierska-Gądek
  • A. Składanowski

  - Future Medicinal Chemistry - Rok 2012

  Many anticancer drugs reduce the integrity of DNA, forming strand breaks. This can cause mutations and cancer or cell death if the lesions are not repaired. Interestingly, DNA repair-deficient cancer cells (e.g., those with BRCA1/2 mutations) have been shown to exhibit increased sensitivity to chemotherapy. Based on this observation, a new therapeutic approach termed 'synthetic lethality' has been developed, in which radiation...

• Cancer-selective, single agent chemoradiosensitising gold nanoparticles

  Publikacja

  • S. Grellet
  • K. Tzelepi
  • M. Roskamp
  • P. Williams
  • A. Sharif
  • R. Slade-Carter
  • P. Goldie
  • N. Whilde
  • M. Śmiałek-Telega
  • N. J. Mason
  • J. Golding

  - PLOS ONE - Rok 2017

  Two nanometre gold nanoparticles (AuNPs), bearing sugar moieties and/or thiol-polyethylene glycol-amine (PEG-amine), were synthesised and evaluated for their in vitro toxicity and ability to radiosensitise cells with 220 kV and 6 MV X-rays, using four cell lines representing normal and cancerous skin and breast tissues. Acute 3 h exposure of cells to AuNPs, bearing PEG-amine only or a 50:50 ratio of alpha-galactose derivative and...

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