Wyniki wyszukiwania dla: Breast cancer
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Overlapping lesion of breast - Not available, 47 - Tissue image [3300730069413631]
Dane BadawczeThis is the histopathological image of HEART, MEDIASTINUM, AND PLEURA tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Overlapping lesion of breast - Not available, 47 - Tissue image [3300730069415951]
Dane BadawczeThis is the histopathological image of HEART, MEDIASTINUM, AND PLEURA tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Overlapping lesion of breast - Not available, 47 - Tissue image [3300730069412031]
Dane BadawczeThis is the histopathological image of HEART, MEDIASTINUM, AND PLEURA tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018858031]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018856901]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018855841]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018857481]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018852521]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018862991]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018851661]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018859461]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018859321]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018855201]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018852601]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018851211]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018858791]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018852411]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [413073001886741]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018857781]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [413073001885421]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018852861]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 60 - Tissue image [4130730018855341]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in University of Warmia and Mazury in Olsztyn and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Cytotoxicity of anthraquinone derivatives (Compound 1-9) towards H226 cancer cell
Dane BadawczeThis study presents absorbance values of formazan product (converted from MTT) which corresponds to the cytotoxicity of anthraquinone derivatives (Compound 1-9) towards H226 cancer cells.
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Cytotoxicity of anthraquinone derivatives (Compound 1-9) towards A549 cancer cells
Dane BadawczeThis study presents absorbance values of formazan product (converted from MTT) which corresponds to the cytotoxicity of anthraquinone derivatives (Compound 1-9) towards A549 cancer cells.
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Cytotoxicity of anthraquinone derivatives (Compound 1-9) towards H460 cancer cell
Dane BadawczeThis study presents absorbance values of formazan product (converted from MTT) which corresponds to the cytotoxicity of anthraquinone derivatives (Compound 1-9) towards H460 cancer cells.
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Adenoid cystic carcinoma - Male, 67 - Tissue image [6280729578143851]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Assessment of cytotoxic and endocrine potential of selected xenobiotics commonly present in food products
PublikacjaMore and more increased intensity of anthropopressure processes can be observed, among other things, in the release of great quantities of synthetic substances into the environment, including the Endocrine Disrupting Compounds (EDC). A vast number of chemical substances is considered to belong to the this group, including substances which occur naturally in the environment, such as mycotoxins and phytoestrogens, and substances...
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Mucinous adenocarcinoma - Female, 67 - Tissue image [6280729578134561]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Transcriptomic Effects of Estrogen Starvation and Induction in the MCF7 Cells. The Meta-analysis of Microarray Results
PublikacjaEstrogen is one of the most important signaling molecules which targets a number of genes. Estrogen levels regulate cell proliferation and a plethora of metabolic processes, which may interfere with a range of medical conditions and drug metabolism. The MCF7 breast cancer cell line, expressing the estrogen receptor α, is a well-studied model of cellular answer to estrogen. The aim of this study was to characterize transcriptomic...
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Design, synthesis and high antitumor potential of new unsymmetrical bisacridine derivatives towards human solid tumors, specifically pancreatic cancers and their unique ability to stabilize DNA G-quadruplexes
PublikacjaNew promising unsymmetrical bisacridine derivatives (UAs), have been developed. Three groupsincluding 36 compounds were synthesized by the condensation of 4-nitro or 4-methylacridinone, imi-dazoacridinone and triazoloacridinone derivatives with 1-nitroacridine compounds linked with anaminoalkyl chain. Cytotoxicity screening revealed the high potency of these compounds against severaltumor cell lines. Particularly, imidazoacridinone-1-nitroacridine...
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Study of proapoptotic activity of anthraquinone derivatives towards H226 cancer cells using flow cytometry
Dane BadawczeThis study presents the fluorescence intensity of Annexin V/7AAD and caspase 3/7 which correspond to the proapoptotic activity of anthraquinone derivatives towards H226 cancer cells.
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Study of proapoptotic activity of anthraquinone derivatives towards A549 cancer cells using flow cytometry
Dane BadawczeThis study presents the fluorescence intensity of Annexin V/7AAD and caspase 3/7 which correspond to the proapoptotic activity of anthraquinone derivatives towards A549 cancer cells.
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LYMPH NODES, Axillary lymph node - Female, 58 - Tissue image [2210630020349771]
Dane BadawczeThis is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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LYMPH NODES, Lymph node axilla, arm - Female, 50 - Tissue image [531073001583571]
Dane BadawczeThis is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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LYMPH NODES, Axillary lymph node - Female, 58 - Tissue image [2210630020348491]
Dane BadawczeThis is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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LYMPH NODES, Lymph node axilla, arm - Female, 50 - Tissue image [7040247104944131]
Dane BadawczeThis is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Adenoid cystic carcinoma - Male, 67 - Tissue image [6280729578145851]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Adenoid cystic carcinoma - Male, 67 - Tissue image [6280729578148561]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Adenoid cystic carcinoma - Male, 67 - Tissue image [6280729578142041]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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LYMPH NODES, Lymph node axilla, arm - Female, 50 - Tissue image [5310730015832581]
Dane BadawczeThis is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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LYMPH NODES, Lymph node axilla, arm - Female, 50 - Tissue image [5310730015838081]
Dane BadawczeThis is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Synthesis, physicochemical and theoretical studies on new rhodium and ruthenium dimers. Relationship between structure and cytotoxic activity
PublikacjaTwo dimeric compounds of the general formulae (Et3NH)2[Rh2(μ2-L)4Cl2] (1) (where L = thiophene-2-carboxylate) and [((η6-p-cymene)Ru)2(μ-Cl)3]PF6 (2) have been synthesized using a new method. The unique anionic complex 1 (space group P bca) has octahedral coordination in which the equatorial positions are occupied by the oxygen atoms of four thiophene-2-carboxylates in a paddle wheel fashion. In complex 2 (space group ), each Ru(II)...
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Synthesis, crystal structure and cytotoxic activity of ruthenium(II) piano-stool complex with N,N-chelating ligand
PublikacjaA mononuclear compound of the general formula [(η6-p-cymene)RuIICl(2,2′-PyBIm)]PF6 has been synthesized from a bidentate N,N-donor ligand, viz. 2,-(2′-pyridyl)benzimidazole (2,2′-PyBIm) and the corresponding chloro-complex [(η6-p-cymene)Ru(μ-Cl)Cl]2 (precursor). The isolated coordination compound was characterized by IR, UV–vis and 1H, 13C NMR spectroscopies. The single crystal X-ray analysis of the complex reveals that the asymmetric...
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DNA-reactive anticancer imidazoacridinone C-1311 is a new inhibitor of hypoxia-inducible factor 1 alpha, vascular endothelial growth factor and tumor angiogenesis
PublikacjaHypoxia-inducible factor 1 (HIF-1) plays a critical role for tumor adaptation to hypoxia and promotes angiogenesis. Antitumor imidazoacridinone C-1311 is a DNA reactive topoisomerase II and FLT3 receptor tyrosine kinase inhibitor selected for phase II clinical trials for breast cancer. Here, we demonstrate the new mechanism of C-1311 action involving HIF-1a, vascular endothelial growth factor (VEGF) and angiogenesis as additional...
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Synthesis and Structure of Novel Hybrid Compounds Containing Phthalazin-1(2H)-imine and 4,5-Dihydro-1H-imidazole Cores and Their Sulfonyl Derivatives with Potential Biological Activities
PublikacjaA novel hybrid compound—2-(4,5-dihydro-1H-imidazol-2-yl)phthalazin-1(2H)-imine (5) was synthesized and converted into di-substituted sulfonamide derivatives 6a–o and phthalazine ring opening products—hydrazonomethylbenzonitriles 7a–m. The newly prepared compounds were characterized using elemental analyses, IR and NMR spectroscopy, as well as mass spectrometry. Single crystal X-ray diffraction data were collected for the representative...
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Role of Human UDP-Glucuronosyltransferases in the Biotransformation of the Triazoloacridinone and Imidazoacridinone Antitumor Agents C-1305 and C-1311 : Highly Selective Substrates for UGT1A10
Publikacja5-Diethylaminoethylamino-8-hydroxyimidazoacridinone, C-1311 (NSC-645809), is an antitumor agent shown to be effective against breast cancer in phase II clinical trials. A similar compound, 5-dimethylaminopropylamino-8-hydroxytriazoloacridinone, C-1305, shows high activity against experimental tumors and is expected to have even more beneficial pharmacological properties than C-1311. Previously published studies showed that these...
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LYMPH NODES, Axillary lymph node - Female, 62 - Tissue image [3300730069404691]
Dane BadawczeThis is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 62 - Tissue image [3300730069416941]
Dane BadawczeThis is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Infiltrating duct carcinoma, NOS - Female, 62 - Tissue image [3300730069418521]
Dane BadawczeThis is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Mucinous adenocarcinoma - Female, 67 - Tissue image [6280729578143311]
Dane BadawczeThis is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.