Wyniki wyszukiwania dla: PDE4

• The influence of food phytochemicals on cyclic phosphodiesterase 4 (PDE4) activity

  Publikacja

  • I. Koss-Mikołajczyk
  • A. Bartoszek-Pączkowska
  • T. Rohrig
  • E. Richling

  - Acta Biochimica Polonica - Rok 2013

  Cyclic phosphodiesterase 4 (PDE4) belongs to family of cyclic phosphodiesterases, which are expressed predominantly in inflammatory cells, airway smooth muscles, cardiovascular tissues and brain. Inhibitors of this family of enzymes found medicinal applications as antidepressants, antiinflamatory drugs (mainly in airway diseases) or antiasthmatics (Ibudilast). PDE4 inhibitors are also being tested for preventing the development...

• PdCl2-catalyzed synthesis of a new class of isocoumarin derivatives containing aminosulfonyl / aminocarboxamide moiety: First identification of a isocoumarin based PDE4 inhibitor

  Publikacja

  • B. Thirupataiah
  • G. Mounika
  • G. Reddy
  • J. Kumar
  • R. Medishetti
  • S. Samarpita
  • M. Rasool
  • J. Mudgal
  • J. Mathew
  • G. Shenoy... i 4 innych

  - European Journal of Medicinal Chemistry - Rok 2021

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• Synthesis of 11,12-dihydro benzo[c]phenanthridines via a Pd-catalyzed unusual construction of isocoumarin ring/FeCl3-mediated intramolecular arene-allyl cyclization: First identification of a benzo[c]phenanthridine based PDE4 inhibitor

  Publikacja

  • B. Thirupataiah
  • G. Reddy
  • S. Ghule
  • J. Kumar
  • G. Mounika
  • J. Mudgal
  • J. Mathew
  • G. Shenoy
  • K. Parsa
  • M. Pal
  • K. A. Hossain

  - BIOORGANIC CHEMISTRY - Rok 2020

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